PMID- 33723166 OWN - NLM STAT- MEDLINE DCOM- 20211119 LR - 20211119 IS - 1998-4138 (Electronic) IS - 1998-4138 (Linking) VI - 17 IP - 1 DP - 2021 Jan-Mar TI - Drug-induced infiltrative lung disease with weekly paclitaxel in breast cancer: Case series. PG - 262-265 LID - 10.4103/jcrt.JCRT_1225_16 [doi] AB - Drug-induced infiltrative lung disease (DI-ILD) can be caused by chemotherapeutic agents, antibiotics, antiarrhythmic drugs, and immunosuppressive agents. Common chemotherapeutic drugs causing DI-ILD include bleomycin, mitomycin C, bis (2-chloroethyl)-l-nitrosourea, cyclophosphamide, busulfan, and methotrexate. Taxanes and trastuzumab are also associated with lung injury. Estimated incidence of paclitaxel-induced lung injury is 0.73%-12%. Although cases of paclitaxel-induced lung injury have been reported previously, we found only one published case report of fatal lung injury caused by paclitaxel use. We are reporting the largest case series of seven patients who developed paclitaxel-induced lung injury along with review of literature. FAU - Raghupathi, Renu AU - Raghupathi R AD - Department of Medical Oncology, Apollo Hospitals Bangalore, Bengaluru, Karnataka, India. FAU - Patil, Channappa AU - Patil C AD - Department of Medical Oncology, Apollo Hospitals Bangalore, Bengaluru, Karnataka, India. FAU - Dhiman, Pravesh AU - Dhiman P AD - Department of Medical Oncology, Apollo Hospitals Bangalore, Bengaluru, Karnataka, India. LA - eng PT - Case Reports PL - India TA - J Cancer Res Ther JT - Journal of cancer research and therapeutics JID - 101249598 RN - 0 (Antibodies, Monoclonal, Humanized) RN - K16AIQ8CTM (pertuzumab) RN - P188ANX8CK (Trastuzumab) RN - P88XT4IS4D (Paclitaxel) SB - IM MH - Adult MH - Aged MH - Antibodies, Monoclonal, Humanized/administration & dosage MH - Antineoplastic Combined Chemotherapy Protocols/administration & dosage/*adverse effects MH - Breast Neoplasms/*drug therapy/pathology MH - Female MH - Humans MH - Lung Diseases/chemically induced/immunology/*pathology MH - Middle Aged MH - Paclitaxel/administration & dosage MH - Pneumonia/chemically induced/immunology/*pathology MH - Prognosis MH - Trastuzumab/administration & dosage OTO - NOTNLM OT - Breast cancer OT - case series OT - chemotherapy OT - drug-induced infiltrative lung disease OT - paclitaxel COIS- None EDAT- 2021/03/17 06:00 MHDA- 2021/11/20 06:00 CRDT- 2021/03/16 06:19 PHST- 2021/03/16 06:19 [entrez] PHST- 2021/03/17 06:00 [pubmed] PHST- 2021/11/20 06:00 [medline] AID - JCanResTher_2021_17_1_262_257465 [pii] AID - 10.4103/jcrt.JCRT_1225_16 [doi] PST - ppublish SO - J Cancer Res Ther. 2021 Jan-Mar;17(1):262-265. doi: 10.4103/jcrt.JCRT_1225_16.