PMID- 33727104 OWN - NLM STAT- MEDLINE DCOM- 20220404 LR - 20220520 IS - 1715-3360 (Electronic) IS - 0008-4182 (Linking) VI - 57 IP - 2 DP - 2022 Apr TI - Refractive change and optical biometry dynamics after 25-gauge vitrectomy in pseudophakic eyes. PG - 82-89 LID - S0008-4182(21)00076-4 [pii] LID - 10.1016/j.jcjo.2021.02.027 [doi] AB - OBJECTIVE: To investigate the refractive change and optical biometry dynamics after 25-gauge vitrectomy without gas tamponade for macular pathology in pseudophakic eyes. DESIGN: A prospective observational case series. PARTICIPANTS: Patients with pseudophakic eyes who were scheduled for vitrectomy owing to macular pathology by an experienced surgeon (T.S.) at the Hayashi Eye Hospital between March 2019 and February 2020. METHODS: The primary endpoint was the change in manifest refraction spherical equivalent (MRSE) between baseline (preoperatively) and 3 months postoperatively. The secondary endpoint was the change in optical biometry parameters obtained by swept-source optical coherence tomography-based biometers between baseline and 3 months postoperatively. Optical biometry parameters included corneal curvature and axial length, evaluated by the IOLMaster 700, and intraocular lens position-that is, lens decentration, lens tilt, and aqueous depth (AQD)-evaluated by the CASIA2. RESULTS: Thirty-four eyes of 34 patients were enrolled. The mean MRSE values at baseline and 3 months postoperatively were -0.70 +/- 1.21 diopter (D) and -0.82 +/- 1.27 D, respectively, showing a significant myopic shift of -0.12 +/- 0.41 D postoperatively (p = 0.043). There was no significant difference between the pre- and postoperative values of the optical biometry parameters, except for the AQD (4.28 +/- 0.34 mm vs 4.27 +/- 0.34 mm; p = 0.019). CONCLUSIONS: The results suggest that replacing the vitreous by the aqueous during vitrectomy induces an average myopic shift of -0.12 D. CI - Copyright (c) 2021 Canadian Ophthalmological Society. Published by Elsevier Inc. All rights reserved. FAU - Sato, Tatsuhiko AU - Sato T AD - Hayashi Eye Hospital, Fukuoka, Japan. Electronic address: tatsusatou@gmail.com. FAU - Yamamoto, Junya AU - Yamamoto J AD - Hayashi Eye Hospital, Fukuoka, Japan. FAU - Korehisa, Haruka AU - Korehisa H AD - Hayashi Eye Hospital, Fukuoka, Japan. FAU - Hayashi, Ken AU - Hayashi K AD - Hayashi Eye Hospital, Fukuoka, Japan. LA - eng PT - Journal Article PT - Observational Study DEP - 20210313 PL - England TA - Can J Ophthalmol JT - Canadian journal of ophthalmology. Journal canadien d'ophtalmologie JID - 0045312 SB - IM MH - Biometry/methods MH - Eye MH - Humans MH - *Lens, Crystalline MH - *Lenses, Intraocular MH - Refraction, Ocular MH - Vitrectomy/methods EDAT- 2021/03/18 06:00 MHDA- 2022/04/05 06:00 CRDT- 2021/03/17 06:06 PHST- 2020/11/27 00:00 [received] PHST- 2021/02/10 00:00 [revised] PHST- 2021/02/16 00:00 [accepted] PHST- 2021/03/18 06:00 [pubmed] PHST- 2022/04/05 06:00 [medline] PHST- 2021/03/17 06:06 [entrez] AID - S0008-4182(21)00076-4 [pii] AID - 10.1016/j.jcjo.2021.02.027 [doi] PST - ppublish SO - Can J Ophthalmol. 2022 Apr;57(2):82-89. doi: 10.1016/j.jcjo.2021.02.027. Epub 2021 Mar 13.