PMID- 33730179
OWN - NLM
STAT- MEDLINE
DCOM- 20210628
LR  - 20210628
IS  - 1432-2323 (Electronic)
IS  - 0364-2313 (Linking)
VI  - 45
IP  - 7
DP  - 2021 Jul
TI  - Impact of Bypass Flow Assessment on Long-Term Outcomes in Patients with Chronic 
      Limb-Threatening Ischemia.
PG  - 2280-2289
LID - 10.1007/s00268-021-06046-y [doi]
AB  - BACKGROUND: Transit time flow meter (TTFM) allows quick and accurate 
      intraoperative graft assessment. The main study goal is to evaluate the influence 
      of graft flow measurements on long-term clinical outcomes in patients with 
      chronic limb-threatening ischemia (CLTI) undergoing bellow the knee (BTK) vein 
      bypass surgery. METHODS: Between January 1st, 1999 and January 1st, 2006, 976 
      CLTI consecutive patients underwent lower extremity bypass surgery. When applying 
      the exclusion criteria, 249 patients were included in the final analysis. Control 
      measurements were performed at the end of the procedure. Patients were divided 
      according to the mean (more/less than 100 ml/min) and diastolic graft flow 
      (more/less than 40 ml/min) values in four groups. The primary endpoints were a 
      major adverse limb event (male) and primary graft patency. RESULTS: After the 
      median follow-up of 68 months, a group with the mean graft flow below 100 ml/min 
      and the diastolic graft flow below 40 ml/min had the highest rates of male 
      (chi(2) = 36.60, DF = 1, P < 0.01, log-rank test) and the worst primary graft 
      patency (chi(2) = 53.05, DF = 1, P < 0.01, log-rank test). CONCLUSION: In patients 
      with CLTI undergoing BTK vein bypass surgery, TTFM parameters, especially 
      combined impact of mean graft flow less than 100 ml/min and diastolic graft flow 
      less than 40 ml/min, were associated with an increased risk of poor long-term 
      male and primary graft patency.
FAU - Cinara, Ilijas
AU  - Cinara I
AD  - Clinic for Vascular and Endovascular Surgery, Clinical Center of Serbia, Dr Koste 
      Todorovica 8, 11000, Belgrade, Serbia.
FAU - Zlatanovic, Petar
AU  - Zlatanovic P
AD  - Clinic for Vascular and Endovascular Surgery, Clinical Center of Serbia, Dr Koste 
      Todorovica 8, 11000, Belgrade, Serbia. petar91goldy@gmail.com.
FAU - Sladojevic, Milos
AU  - Sladojevic M
AD  - Clinic for Vascular and Endovascular Surgery, Clinical Center of Serbia, Dr Koste 
      Todorovica 8, 11000, Belgrade, Serbia.
AD  - Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
FAU - Tomic, Ivan
AU  - Tomic I
AD  - Clinic for Vascular and Endovascular Surgery, Clinical Center of Serbia, Dr Koste 
      Todorovica 8, 11000, Belgrade, Serbia.
AD  - Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
FAU - Mutavdzic, Perica
AU  - Mutavdzic P
AD  - Clinic for Vascular and Endovascular Surgery, Clinical Center of Serbia, Dr Koste 
      Todorovica 8, 11000, Belgrade, Serbia.
AD  - Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
FAU - Ducic, Stefan
AU  - Ducic S
AD  - Clinic for Vascular and Endovascular Surgery, Clinical Center of Serbia, Dr Koste 
      Todorovica 8, 11000, Belgrade, Serbia.
FAU - Vujcic, Aleksandra
AU  - Vujcic A
AD  - Clinic for Vascular and Endovascular Surgery, Clinical Center of Serbia, Dr Koste 
      Todorovica 8, 11000, Belgrade, Serbia.
FAU - Davidovic, Lazar
AU  - Davidovic L
AD  - Clinic for Vascular and Endovascular Surgery, Clinical Center of Serbia, Dr Koste 
      Todorovica 8, 11000, Belgrade, Serbia.
AD  - Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20210317
PL  - United States
TA  - World J Surg
JT  - World journal of surgery
JID - 7704052
SB  - IM
MH  - Humans
MH  - Ischemia/surgery
MH  - Limb Salvage
MH  - Lower Extremity/surgery
MH  - Male
MH  - *Peripheral Vascular Diseases
MH  - Retrospective Studies
MH  - Risk Factors
MH  - Treatment Outcome
MH  - *Vascular Grafting
MH  - Vascular Patency
EDAT- 2021/03/18 06:00
MHDA- 2021/06/29 06:00
CRDT- 2021/03/17 17:42
PHST- 2021/02/07 00:00 [accepted]
PHST- 2021/03/18 06:00 [pubmed]
PHST- 2021/06/29 06:00 [medline]
PHST- 2021/03/17 17:42 [entrez]
AID - 10.1007/s00268-021-06046-y [pii]
AID - 10.1007/s00268-021-06046-y [doi]
PST - ppublish
SO  - World J Surg. 2021 Jul;45(7):2280-2289. doi: 10.1007/s00268-021-06046-y. Epub 
      2021 Mar 17.