PMID- 33734483
OWN - NLM
STAT- MEDLINE
DCOM- 20210811
LR  - 20210811
IS  - 1099-1166 (Electronic)
IS  - 0885-6230 (Linking)
VI  - 36
IP  - 9
DP  - 2021 Sep
TI  - The impact of auditory hallucinations on "living well" with dementia: Findings 
      from the IDEAL programme.
PG  - 1370-1377
LID - 10.1002/gps.5533 [doi]
AB  - OBJECTIVE: To determine whether auditory hallucinations in community-dwelling 
      people with dementia (PwD) living in the community impacted on quality of life 
      (QoL), subjective wellbeing and life satisfaction. DESIGN: Cross-sectional cohort 
      study. SETTINGS AND PARTICIPANTS: 1251 community-dwelling PwD and caregivers were 
      included in this study. MEASURES: Neuropsychiatric Inventory Questionnaire 
      completed by caregiver interview. Mean differences between the absence and 
      presence of auditory hallucinations were compared to scores on three validated 
      measures of living well: QoL in Alzheimer's disease scale (QoL-AD), World Health 
      Organization-Five Well-being Index and Satisfaction with Life Scale. Analysis of 
      covariance determined the confounding contributions of cognition via Mini-Mental 
      State Examination, depression via Geriatric Depression Scale-10, caregiver stress 
      via Relative Stress Scale and whether antipsychotic drugs were prescribed. 
      RESULTS: Auditory hallucinations were associated with lower scores for QoL 
      (p < 0.001, eta(2)  = 0.01), wellbeing (p < 0.001, eta(2)  = 0.02) and life 
      satisfaction (p < 0.001, eta(2)  = 0.01). After controlling for background 
      measures, which were potential confounds, the relationship between auditory 
      hallucinations and QoL (p = 0.04, peta(2)  = 0.01) and wellbeing (p < 0.000, peta(2) 
       = 0.02) remained significant but there was no significant association with life 
      satisfaction. CONCLUSION: Auditory hallucinations are associated with lower QoL 
      and wellbeing in PwD living in the community. This has implications for targeted 
      therapies in PwD with psychotic symptoms.
CI  - (c) 2021 The Authors. International Journal of Geriatric Psychiatry published by 
      John Wiley & Sons Ltd.
FAU - Choi, Aaron
AU  - Choi A
AUID- ORCID: 0000-0001-7454-4527
AD  - College of Medicine and Health, University of Exeter, Exeter, UK.
FAU - Ballard, Clive
AU  - Ballard C
AUID- ORCID: 0000-0003-0022-5632
AD  - College of Medicine and Health, University of Exeter, Exeter, UK.
FAU - Martyr, Anthony
AU  - Martyr A
AUID- ORCID: 0000-0002-1702-8902
AD  - College of Medicine and Health, University of Exeter, Exeter, UK.
FAU - Collins, Rachel
AU  - Collins R
AUID- ORCID: 0000-0002-3405-7932
AD  - College of Medicine and Health, University of Exeter, Exeter, UK.
FAU - Morris, Robin G
AU  - Morris RG
AUID- ORCID: 0000-0001-7767-5258
AD  - Department of Psychology, King's College London Institute of Psychiatry, 
      Psychology and Neuroscience, London, UK.
FAU - Clare, Linda
AU  - Clare L
AUID- ORCID: 0000-0003-3989-5318
AD  - College of Medicine and Health, University of Exeter, Exeter, UK.
AD  - NIHR Applied Research Collaboration South-West Peninsula, University of Exeter, 
      Exeter, UK.
CN  - IDEAL programme team
LA  - eng
GR  - DH_/Department of Health/United Kingdom
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20210325
PL  - England
TA  - Int J Geriatr Psychiatry
JT  - International journal of geriatric psychiatry
JID - 8710629
SB  - IM
MH  - Aged
MH  - *Alzheimer Disease
MH  - Caregivers
MH  - Cross-Sectional Studies
MH  - Hallucinations
MH  - Humans
MH  - Neuropsychological Tests
MH  - *Quality of Life
OTO - NOTNLM
OT  - psychosis
OT  - quality of life
OT  - satisfaction with life
OT  - wellbeing
EDAT- 2021/03/19 06:00
MHDA- 2021/08/12 06:00
CRDT- 2021/03/18 12:54
PHST- 2021/02/15 00:00 [received]
PHST- 2021/03/04 00:00 [accepted]
PHST- 2021/03/19 06:00 [pubmed]
PHST- 2021/08/12 06:00 [medline]
PHST- 2021/03/18 12:54 [entrez]
AID - 10.1002/gps.5533 [doi]
PST - ppublish
SO  - Int J Geriatr Psychiatry. 2021 Sep;36(9):1370-1377. doi: 10.1002/gps.5533. Epub 
      2021 Mar 25.