PMID- 33737592
OWN - NLM
STAT- MEDLINE
DCOM- 20211012
LR  - 20211012
IS  - 2045-2322 (Electronic)
IS  - 2045-2322 (Linking)
VI  - 11
IP  - 1
DP  - 2021 Mar 18
TI  - Microsomic and macrosomic body structure in children and adolescents affected by 
      syndromes or diseases associated with neurodysfunction.
PG  - 6349
LID - 10.1038/s41598-021-85587-7 [doi]
LID - 6349
AB  - In Poland the issue of microsomic body structure (micro-SBS) and macrosomic body 
      structure (macro-SBS) has so far been overlooked. Up until now only a small 
      amount of data have been published, most often as an overview of the problem. The 
      current study was designed to investigate the co-occurrence of 
      microsomic/macrosomic body structure (micro/macro-SBS) and congenital nervous 
      system disorders or neurological syndromes with symptoms visible from infancy, 
      based on essential data acquired during admission procedures at a neurological 
      rehabilitation ward for children and adolescents. The study applied a 
      retrospective analysis of data collected during hospitalization of 327 children 
      and adolescents, aged 4-18 years who had been affected since infancy by 
      congenital disorders of the nervous system and/or neurological syndromes 
      associated with a minimum of one neurodysfunction. To identify subjects with 
      microsomic or macrosomic body structure in the group of children and adolescents, 
      the adopted criteria took into account z-score values for body height (z-score 
      Ht), body weight (z-score Wt), head circumference (z-score HC), BMI (z-score BMI) 
      and head circumference index (z-score HCI). The rates of micro/macro-SBS in the 
      study group amounted to 7.3% and 0.6%, respectively. The findings show a more 
      frequent co-occurrence of, as well as statistically significant correlations 
      between, micro/macro-SBS and type of spasticity (cerebral palsy) (p = 0.024) as 
      well as hydrocephalus not treated surgically (p < 0.001). Macro-SBS was found to 
      more frequently co-occur with hemiplegia and hydrocephalus not treated 
      surgically.
FAU - Perenc, Lidia
AU  - Perenc L
AD  - Department of Physiotherapy, Institute of Health Sciences, College of Medical 
      Sciences, University of Rzeszow, Rzeszow, Poland.
FAU - Guzik, Agnieszka
AU  - Guzik A
AD  - Department of Physiotherapy, Institute of Health Sciences, College of Medical 
      Sciences, University of Rzeszow, Rzeszow, Poland. agnieszkadepa2@wp.pl.
FAU - Podgorska-Bednarz, Justyna
AU  - Podgorska-Bednarz J
AD  - Department of Physiotherapy, Institute of Health Sciences, College of Medical 
      Sciences, University of Rzeszow, Rzeszow, Poland.
FAU - Druzbicki, Mariusz
AU  - Druzbicki M
AD  - Department of Physiotherapy, Institute of Health Sciences, College of Medical 
      Sciences, University of Rzeszow, Rzeszow, Poland.
LA  - eng
PT  - Journal Article
DEP - 20210318
PL  - England
TA  - Sci Rep
JT  - Scientific reports
JID - 101563288
SB  - IM
MH  - Adolescent
MH  - Body Height
MH  - Body Mass Index
MH  - Body Weight
MH  - Cephalometry
MH  - Child
MH  - Child, Preschool
MH  - Female
MH  - Fetal Growth Retardation/*epidemiology/physiopathology
MH  - Humans
MH  - Male
MH  - Neurodevelopmental Disorders/*epidemiology/genetics
MH  - Obesity/*epidemiology/physiopathology
MH  - Poland/epidemiology
MH  - Retrospective Studies
PMC - PMC7973426
COIS- The authors declare no competing interests.
EDAT- 2021/03/20 06:00
MHDA- 2021/10/13 06:00
PMCR- 2021/03/18
CRDT- 2021/03/19 06:55
PHST- 2020/06/16 00:00 [received]
PHST- 2021/02/26 00:00 [accepted]
PHST- 2021/03/19 06:55 [entrez]
PHST- 2021/03/20 06:00 [pubmed]
PHST- 2021/10/13 06:00 [medline]
PHST- 2021/03/18 00:00 [pmc-release]
AID - 10.1038/s41598-021-85587-7 [pii]
AID - 85587 [pii]
AID - 10.1038/s41598-021-85587-7 [doi]
PST - epublish
SO  - Sci Rep. 2021 Mar 18;11(1):6349. doi: 10.1038/s41598-021-85587-7.