PMID- 33747342
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220421
IS  - 1939-4551 (Print)
IS  - 1939-4551 (Electronic)
IS  - 1939-4551 (Linking)
VI  - 14
IP  - 3
DP  - 2021 Mar
TI  - Dyslipidemia among allergic rhinitis patients: Frequency and risk factors.
PG  - 100523
LID - 10.1016/j.waojou.2021.100523 [doi]
LID - 100523
AB  - BACKGROUND: Although cumulative data strongly suggest an association between 
      dyslipidemia and allergic disorders, especially asthma, evidence regarding 
      allergic rhinitis (AR) is lacking. We aimed to assess frequency and associated 
      risk factors of dyslipidemia among patients with AR. METHODS: The current study 
      is a cross-sectional study that recruited 150 AR patients by systematic 
      randomization. Blood samples for serum lipid profile, total immunoglobulin E 
      (IgE) and serum interleukin-17A (IL-17A) were withdrawn from all patients. 
      RESULTS: Dyslipidemia was prevalent in 84 AR patients (56%). Higher levels of 
      total IgE, IL17-A, and sensitization to hay dust and mixed mites significantly 
      increased the risk of dyslipidemia among AR patients by 1.004, 1.062, 4.057 and 
      3.652 respectively (P < 0.05). CONCLUSION: High serum total IgE level, high serum 
      IL-17A level, and sensitization to hay dust and mixed mites are independent risk 
      factors for dyslipidemia among AR patients.
CI  - (c) 2021 The Author(s).
FAU - Sheha, Dina S
AU  - Sheha DS
AD  - Department of Internal Medicine, Allergy and Clinical Immunology, Faculty of 
      Medicine, Ain Shams University, Cairo, Egypt.
FAU - El-Korashi, Lobna A
AU  - El-Korashi LA
AD  - Department of Medical Microbiology and Immunology, Faculty of Medicine, Zagazig 
      University, Zagazig, Egypt.
FAU - AbdAllah, Amany M
AU  - AbdAllah AM
AD  - Department of Family Medicine, Faculty of Medicine, Zagazig University, Zagazig, 
      Egypt.
FAU - El-Begermy, Marwa M
AU  - El-Begermy MM
AD  - Department of Otorhinolaryngology, Faculty of Medicine, Ain Shams University, 
      Cairo, Egypt.
FAU - Elmahdi, Amira R
AU  - Elmahdi AR
AD  - Department of Internal Medicine, Allergy and Clinical Immunology, Faculty of 
      Medicine, Ain Shams University, Cairo, Egypt.
LA  - eng
PT  - Journal Article
DEP - 20210305
PL  - United States
TA  - World Allergy Organ J
JT  - The World Allergy Organization journal
JID - 101481283
PMC - PMC7937983
OTO - NOTNLM
OT  - Allergic rhinitis
OT  - Dyslipidemia
OT  - Interleukin-17
COIS- The authors report no conflicts of interest in this work.
EDAT- 2021/03/23 06:00
MHDA- 2021/03/23 06:01
PMCR- 2021/03/05
CRDT- 2021/03/22 08:13
PHST- 2020/08/11 00:00 [received]
PHST- 2021/01/19 00:00 [revised]
PHST- 2021/02/01 00:00 [accepted]
PHST- 2021/03/22 08:13 [entrez]
PHST- 2021/03/23 06:00 [pubmed]
PHST- 2021/03/23 06:01 [medline]
PHST- 2021/03/05 00:00 [pmc-release]
AID - S1939-4551(21)00017-X [pii]
AID - 100523 [pii]
AID - 10.1016/j.waojou.2021.100523 [doi]
PST - epublish
SO  - World Allergy Organ J. 2021 Mar 5;14(3):100523. doi: 
      10.1016/j.waojou.2021.100523. eCollection 2021 Mar.