PMID- 33752112
OWN - NLM
STAT- MEDLINE
DCOM- 20210510
LR  - 20210510
IS  - 1873-7072 (Electronic)
IS  - 0308-8146 (Linking)
VI  - 354
DP  - 2021 Aug 30
TI  - Development and validation of the one-step purification method coupled to 
      LC-MS/MS for simultaneous determination of four aflatoxins in fermented tea.
PG  - 129497
LID - S0308-8146(21)00503-3 [pii]
LID - 10.1016/j.foodchem.2021.129497 [doi]
AB  - Aflatoxin B(1) is the potential chemical contaminant of most concern during the 
      production and storage of fermented tea. In this work, a simple, fast, sensitive, 
      accurate, and inexpensive method has been developed and validated for the 
      simultaneous detection of four aflatoxins in fermented tea based on a modified 
      sample pretreatment method and liquid chromatography-tandem mass spectrometry 
      (LC-MS/MS). Aflatoxins were extracted using acetonitrile and purified using mixed 
      fillers (carboxyl multiwalled carbon nanotubes, hydrophilic-lipophilic balance, 
      silica gel). Under optimum LC-MS conditions, the limits of quantification (LOQs) 
      were 0.02-0.5 microg.kg(-1). Recoveries from aflatoxins-fortified tea samples 
      (1-12 microg.kg(-1)) were in the range of 78.94-105.23% with relative standard 
      deviations (RSDs) less than 18.20%. The proposed method was applied successfully 
      to determine aflatoxin levels in fermented tea samples.
CI  - Copyright (c) 2021 Elsevier Ltd. All rights reserved.
FAU - Zhou, Haiyan
AU  - Zhou H
AD  - SIBS-UGENT-SJTU Joint Laboratory of Mycotoxin Research, CAS Key Laboratory of 
      Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and 
      Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 
      China.
FAU - Liu, Na
AU  - Liu N
AD  - SIBS-UGENT-SJTU Joint Laboratory of Mycotoxin Research, CAS Key Laboratory of 
      Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and 
      Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 
      China.
FAU - Yan, Zheng
AU  - Yan Z
AD  - SIBS-UGENT-SJTU Joint Laboratory of Mycotoxin Research, CAS Key Laboratory of 
      Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and 
      Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 
      China.
FAU - Yu, Dianzhen
AU  - Yu D
AD  - SIBS-UGENT-SJTU Joint Laboratory of Mycotoxin Research, CAS Key Laboratory of 
      Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and 
      Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 
      China.
FAU - Wang, Lan
AU  - Wang L
AD  - SIBS-UGENT-SJTU Joint Laboratory of Mycotoxin Research, CAS Key Laboratory of 
      Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and 
      Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 
      China.
FAU - Wang, Kunbo
AU  - Wang K
AD  - Key Laboratory of Tea Science of Ministry of Education, Hunan Agricultural 
      University, Changsha, Hunan 410128, PR China.
FAU - Wei, Xinlin
AU  - Wei X
AD  - School of Agriculture and Biology, Shanghai Jiao Tong University, Minhang, 
      Shanghai 200240, PR China.
FAU - Wu, Aibo
AU  - Wu A
AD  - SIBS-UGENT-SJTU Joint Laboratory of Mycotoxin Research, CAS Key Laboratory of 
      Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and 
      Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 
      China. Electronic address: abwu@sibs.ac.cn.
LA  - eng
PT  - Journal Article
DEP - 20210308
PL  - England
TA  - Food Chem
JT  - Food chemistry
JID - 7702639
RN  - 0 (Aflatoxins)
RN  - 0 (Nanotubes, Carbon)
RN  - 0 (Teas, Herbal)
RN  - 60650-90-0 (Silica Gel)
SB  - IM
MH  - Aflatoxins/*analysis/isolation & purification
MH  - Chromatography, High Pressure Liquid/*methods
MH  - Hydrophobic and Hydrophilic Interactions
MH  - Limit of Detection
MH  - Nanotubes, Carbon/chemistry
MH  - Reproducibility of Results
MH  - Silica Gel/chemistry
MH  - Tandem Mass Spectrometry
MH  - Teas, Herbal/*analysis
OTO - NOTNLM
OT  - Aflatoxins
OT  - Liquid chromatography-tandem mass spectrometry
OT  - Matrix effects
OT  - One-step purification
OT  - Tea
EDAT- 2021/03/23 06:00
MHDA- 2021/05/11 06:00
CRDT- 2021/03/22 20:21
PHST- 2020/10/24 00:00 [received]
PHST- 2021/01/20 00:00 [revised]
PHST- 2021/02/25 00:00 [accepted]
PHST- 2021/03/23 06:00 [pubmed]
PHST- 2021/05/11 06:00 [medline]
PHST- 2021/03/22 20:21 [entrez]
AID - S0308-8146(21)00503-3 [pii]
AID - 10.1016/j.foodchem.2021.129497 [doi]
PST - ppublish
SO  - Food Chem. 2021 Aug 30;354:129497. doi: 10.1016/j.foodchem.2021.129497. Epub 2021 
      Mar 8.