PMID- 33756439
OWN - NLM
STAT- MEDLINE
DCOM- 20210707
LR  - 20220531
IS  - 2211-0356 (Electronic)
IS  - 2211-0348 (Linking)
VI  - 51
DP  - 2021 Jun
TI  - Myelin oligodendrocyte glycoprotein antibody-associated disorders coexisting with 
      ankylosing spondylitis: Potential association between demyelination and tumor 
      necrosis factor inhibitors.
PG  - 102889
LID - S2211-0348(21)00156-5 [pii]
LID - 10.1016/j.msard.2021.102889 [doi]
AB  - Myelin oligodendrocyte glycoprotein antibody-associated disorders (MOGAD) is a 
      newly described demyelinating disease. Ankylosing spondylitis (AS) is an 
      inflammatory disease that predominantly affects the axial skeleton. Treatments 
      for AS, such as tumor necrosis factor alpha (TNFalpha) inhibitors, may induce 
      demyelination. We report the first case of MOGAD coexisting with AS and postulate 
      a potential association with TNFalpha inhibitors. Further studies are needed to 
      clarify the risk of demyelinating events following anti-TNFalpha therapy and to 
      elucidate the relationship between MOGAD and AS.
CI  - Copyright (c) 2021. Published by Elsevier B.V.
FAU - Luo, Wenjng
AU  - Luo W
AD  - Department of Neurology, The Third Affiliated Hospital of Sun Yat-sen University, 
      Guangzhou, China.
FAU - Li, Rui
AU  - Li R
AD  - Department of Neurology, The Third Affiliated Hospital of Sun Yat-sen University, 
      Guangzhou, China.
FAU - Chang, Yanyu
AU  - Chang Y
AD  - Department of Neurology, The Third Affiliated Hospital of Sun Yat-sen University, 
      Guangzhou, China.
FAU - She, Hongda
AU  - She H
AD  - Department of Neurology, The Third Affiliated Hospital of Sun Yat-sen University, 
      Guangzhou, China.
FAU - Kermode, Allan G
AU  - Kermode AG
AD  - Department of Neurology, The Third Affiliated Hospital of Sun Yat-sen University, 
      Guangzhou, China; Center for Neuromuscular and Neurological Disorders, University 
      of Western Australia, Perth, WA, Australia; Department of Neurology, Sir Charles 
      Gairdner Hospital, Queen Elizabeth II Medical Centre, Perth, WA, Australia; 
      Institute of Immunology and Infectious Diseases, Murdoch University, Perth, WA, 
      Australia.
FAU - Qiu, Wei
AU  - Qiu W
AD  - Department of Neurology, The Third Affiliated Hospital of Sun Yat-sen University, 
      Guangzhou, China. Electronic address: qiuwei120@vip.163.com.
LA  - eng
PT  - Case Reports
PT  - Letter
DEP - 20210310
PL  - Netherlands
TA  - Mult Scler Relat Disord
JT  - Multiple sclerosis and related disorders
JID - 101580247
RN  - 0 (Autoantibodies)
RN  - 0 (Myelin-Oligodendrocyte Glycoprotein)
RN  - 0 (Tumor Necrosis Factor Inhibitors)
SB  - IM
MH  - Autoantibodies
MH  - *Demyelinating Diseases/chemically induced
MH  - Humans
MH  - Myelin-Oligodendrocyte Glycoprotein
MH  - *Spondylitis, Ankylosing/complications/drug therapy
MH  - Tumor Necrosis Factor Inhibitors
COIS- Declaration of Competing Interest None declared.
EDAT- 2021/03/24 06:00
MHDA- 2021/07/08 06:00
CRDT- 2021/03/23 20:26
PHST- 2020/09/18 00:00 [received]
PHST- 2021/01/24 00:00 [revised]
PHST- 2021/03/07 00:00 [accepted]
PHST- 2021/03/24 06:00 [pubmed]
PHST- 2021/07/08 06:00 [medline]
PHST- 2021/03/23 20:26 [entrez]
AID - S2211-0348(21)00156-5 [pii]
AID - 10.1016/j.msard.2021.102889 [doi]
PST - ppublish
SO  - Mult Scler Relat Disord. 2021 Jun;51:102889. doi: 10.1016/j.msard.2021.102889. 
      Epub 2021 Mar 10.