PMID- 33763268
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220421
IS  - 2090-6560 (Print)
IS  - 2090-6579 (Electronic)
IS  - 2090-6579 (Linking)
VI  - 2021
DP  - 2021
TI  - Thrombosis as the First Manifestation of Granulomatosis with Polyangiitis Disease 
      in an Adolescent.
PG  - 5520258
LID - 10.1155/2021/5520258 [doi]
LID - 5520258
AB  - BACKGROUND: Granulomatosis with polyangiitis disease (GPA) is a rare vasculitis 
      characterized by granulomatous inflammation of respiratory tracts, 
      glomerulonephritis, and vasculitis of other organs. Case Presentation. A 
      13-year-old girl was referred due to swelling and pain on her left arm. The 
      Doppler and compression ultrasonography showed noncompressible left brachial and 
      axillary vein thrombosis. Sinus computed tomography (CT) demonstrated 
      pansinusitis, and spiral chest CT showed alveolar hemorrhage. Laboratory tests 
      showed hematuria, proteinuria, and highly positive antineutrophil cytoplasmic 
      antibody (cANCA). Laboratory tests of coagulopathy were normal. The patient was 
      recognized as a case of GPA. CONCLUSION: Although GPA is not frequently 
      associated with thrombosis especially in children, this is the first report that 
      shows thrombosis may be the first manifestation of GPA in an adolescent.
CI  - Copyright (c) 2021 Mohsen Jari.
FAU - Jari, Mohsen
AU  - Jari M
AUID- ORCID: 0000-0001-7001-6794
AD  - Department of Pediatric Rheumatology, Imam Hossein Children's Hospital, Isfahan 
      University of Medical Sciences, Isfahan, Iran.
LA  - eng
PT  - Case Reports
DEP - 20210303
PL  - United States
TA  - Case Rep Hematol
JT  - Case reports in hematology
JID - 101576456
PMC - PMC7946471
COIS- The author declares no conflicts of interest.
EDAT- 2021/03/26 06:00
MHDA- 2021/03/26 06:01
PMCR- 2021/03/03
CRDT- 2021/03/25 06:30
PHST- 2021/01/14 00:00 [received]
PHST- 2021/02/22 00:00 [revised]
PHST- 2021/02/28 00:00 [accepted]
PHST- 2021/03/25 06:30 [entrez]
PHST- 2021/03/26 06:00 [pubmed]
PHST- 2021/03/26 06:01 [medline]
PHST- 2021/03/03 00:00 [pmc-release]
AID - 10.1155/2021/5520258 [doi]
PST - epublish
SO  - Case Rep Hematol. 2021 Mar 3;2021:5520258. doi: 10.1155/2021/5520258. eCollection 
      2021.