PMID- 33773028
OWN - NLM
STAT- MEDLINE
DCOM- 20210524
LR  - 20210707
IS  - 1473-2165 (Electronic)
IS  - 1473-2130 (Print)
IS  - 1473-2130 (Linking)
VI  - 20
IP  - 6
DP  - 2021 Jun
TI  - Helium plasma dermal resurfacing: VISIA CR assessment of facial spots, pores, and 
      wrinkles-Preliminary findings.
PG  - 1668-1678
LID - 10.1111/jocd.14106 [doi]
AB  - OBJECTIVES: Effects of low energy, single-pass helium plasma dermal resurfacing 
      (PDR) treatment on brown spots, enlarged pores, and wrinkles-preliminary 
      findings. METHODS: Twenty two subjects (64.6 +/- 6.6 years) with Fitzpatrick 
      Wrinkle and Elastosis Scale score (FWS) of </=2 and seeking improvement of facial 
      appearance were included in this subanalysis. All subjects received a single, 
      one-pass, full face, and low power helium PDR treatment. Standard digital images 
      were collected using the VISIA-CR (Canfield Scientific Inc.) at baseline and 
      3 months after treatment with images assessed for improvement in FWS and for 
      improvements in brown spots, enlarged pores, and wrinkles by proprietary 
      automated image processing algorithms. RESULTS: Nearly all subjects demonstrated 
      >/=1-point improvement in FWS and also reported improvement per modified Global 
      Aesthetic Improvement Scale query. The numbers of brown spots and enlarged pores 
      decreased by 45.1% and 28.3%, respectively. Stratification of brown spots data by 
      presence or absence of post-inflammatory hyperpigmentation revealed paradoxically 
      conflicting data. The improvement detected in wrinkle area and mean wrinkle 
      thickness was less pronounced with overall reductions of 13.4% and 4.8%, 
      respectively. 37 Non-serious adverse events (AEs) in 22 subjects were reported 
      with most resolving within 14 days or less, and no serious AEs were observed. 
      CONCLUSIONS: While longer-term follow-up is needed, these early study results 
      show that one single-pass, low energy helium PDR treatment improves facial skin 
      appearance both qualitatively and quantitatively. Studies evaluating higher 
      energy levels and multiple treatment passes are ongoing.
CI  - (c) 2021 The Authors. Journal of Cosmetic Dermatology published by Wiley 
      Periodicals LLC.
FAU - Holcomb, John David
AU  - Holcomb JD
AUID- ORCID: 0000-0002-5402-9779
AD  - Holcomb - Kreithen Plastic Surgery and Medspa, Sarasota, FL, USA.
LA  - eng
GR  - Apyx Medical Corporation/
PT  - Journal Article
DEP - 20210407
PL  - England
TA  - J Cosmet Dermatol
JT  - Journal of cosmetic dermatology
JID - 101130964
RN  - 0 (Plasma Gases)
RN  - 206GF3GB41 (Helium)
SB  - IM
MH  - Face
MH  - Helium
MH  - Humans
MH  - *Hyperpigmentation
MH  - *Plasma Gases
MH  - *Skin Aging
MH  - Treatment Outcome
PMC - PMC8251577
OTO - NOTNLM
OT  - Skin resurfacing
OT  - helium plasma
OT  - skin pore
OT  - skin spot
OT  - wrinkle
EDAT- 2021/03/28 06:00
MHDA- 2021/05/25 06:00
PMCR- 2021/07/02
CRDT- 2021/03/27 17:41
PHST- 2021/03/01 00:00 [revised]
PHST- 2020/09/15 00:00 [received]
PHST- 2021/03/19 00:00 [accepted]
PHST- 2021/03/28 06:00 [pubmed]
PHST- 2021/05/25 06:00 [medline]
PHST- 2021/03/27 17:41 [entrez]
PHST- 2021/07/02 00:00 [pmc-release]
AID - JOCD14106 [pii]
AID - 10.1111/jocd.14106 [doi]
PST - ppublish
SO  - J Cosmet Dermatol. 2021 Jun;20(6):1668-1678. doi: 10.1111/jocd.14106. Epub 2021 
      Apr 7.