PMID- 33779045 OWN - NLM STAT- MEDLINE DCOM- 20211210 LR - 20211214 IS - 1754-9485 (Electronic) IS - 1754-9477 (Linking) VI - 65 IP - 7 DP - 2021 Dec TI - Factors predicting positive CT mesenteric angiography results in lower gastrointestinal haemorrhage prior to consideration of intra-arterial angio-embolisation. PG - 841-845 LID - 10.1111/1754-9485.13176 [doi] AB - INTRODUCTION: Lower gastrointestinal haemorrhage (LGIH) is a challenging phenomenon in a comorbid, elderly population. CT mesenteric angiography (CTMA) allows localisation of the site of haemorrhage, and provides a target for interventional techniques, but the intermittent nature of LGIH makes it challenging to reliably demonstrate extravasation. This study aimed to identify objective factors that may predict scan outcomes. METHODS: In this retrospective cohort study, all patients undergoing CTMA for LGIH at Monash Health from January 2011 to December 2019 (n = 854) were included. Baseline patient characteristics included age, bowel resection/endoscopic intervention within the past 14 days, known bowel malignancy, anticoagulant/antiplatelet use, duration of symptoms, vital signs, transfusion requirements in the past 24 h and investigation results (recent haemoglobin levels, platelet count, international normalised ratio and creatinine levels). Univariate analysis was performed, and significant factors were entered into a multivariate model. RESULTS: The final multivariate model was statistically significant (P < 0.001) and consisted of bowel resection/endoscopic intervention within the past 14 days (OR = 2.15), use of antiplatelet agents (OR = 2.03), blood transfusion requirement greater than 3 units per 24 h (OR = 1.79), systolic blood pressure less than 100 mmHg (OR = 1.56) and heart rate greater than 100 beats per minute (OR = 1.52). CONCLUSION: The factors identified above are objective, independently associated with positive scan outcomes, readily available to radiologists and are useful for more judicious patient selection. CI - (c) 2021 The Royal Australian and New Zealand College of Radiologists. FAU - Smith, Rohan Stuart AU - Smith RS AUID- ORCID: 0000-0001-6236-8263 AD - Monash Medical Centre, Monash Health, Clayton, Victoria, Australia. FAU - Tan, Stephanie Wei Jia AU - Tan SWJ AD - Dandenong and Districts Hospital, Monash Health, Dandenong, Victoria, Australia. FAU - Heath-Kalgutkar, Genevieve Ann AU - Heath-Kalgutkar GA AD - Monash Medical Centre, Monash Health, Clayton, Victoria, Australia. FAU - Tran, Vu Hoang AU - Tran VH AD - Monash Medical Centre, Monash Health, Clayton, Victoria, Australia. FAU - Rajagopalan, Ashray AU - Rajagopalan A AUID- ORCID: 0000-0002-5421-7120 AD - Monash Medical Centre, Monash Health, Clayton, Victoria, Australia. FAU - Buckenham, Tim AU - Buckenham T AD - Dandenong and Districts Hospital, Monash Health, Dandenong, Victoria, Australia. LA - eng PT - Journal Article DEP - 20210328 PL - Australia TA - J Med Imaging Radiat Oncol JT - Journal of medical imaging and radiation oncology JID - 101469340 SB - IM MH - Aged MH - Angiography MH - Computed Tomography Angiography MH - *Embolization, Therapeutic MH - *Gastrointestinal Hemorrhage/diagnostic imaging/therapy MH - Humans MH - Retrospective Studies OTO - NOTNLM OT - computed tomography angiography OT - gastrointestinal haemorrhage OT - haemorrhage OT - lower gastrointestinal tract OT - multidetector computed tomography EDAT- 2021/03/30 06:00 MHDA- 2021/12/15 06:00 CRDT- 2021/03/29 07:00 PHST- 2020/10/19 00:00 [received] PHST- 2021/03/07 00:00 [accepted] PHST- 2021/03/30 06:00 [pubmed] PHST- 2021/12/15 06:00 [medline] PHST- 2021/03/29 07:00 [entrez] AID - 10.1111/1754-9485.13176 [doi] PST - ppublish SO - J Med Imaging Radiat Oncol. 2021 Dec;65(7):841-845. doi: 10.1111/1754-9485.13176. Epub 2021 Mar 28.