PMID- 33795021
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210408
IS  - 2055-0294 (Print)
IS  - 2055-0294 (Electronic)
IS  - 2055-0294 (Linking)
VI  - 7
IP  - 1
DP  - 2021 Apr 2
TI  - An application of multi-criteria decision-making approach to sustainable drug 
      shortages management: evidence from a developing country.
PG  - 14
LID - 10.1186/s40780-021-00200-3 [doi]
LID - 14
AB  - BACKGROUND: Drug shortage is a significant public health problem, especially for 
      drugs related to life threatening conditions. Almost all countries affected by 
      variety of supply problems and spent a considerable amount of time and resources 
      responding to shortage. The aim of present study is to determine and prioritize 
      strategies to achieve best solutions for these considerable healthcare system 
      challenges and to evaluate this strategies base on practical criteria. METHODS: 
      To achieve the study objectives, the research was conducted in two phases. 
      Determining of the strategies to control drug shortage, and comprehensive 
      assessments of priority of possible strategies. For each phase, a self-design 
      questionnaire was developed. The five main managerial strategies dimensions 
      including: regulatory, financial, supply chain, information system and 
      policy-making were set out. Forty-five alternatives were elicited from 
      literature, and were evaluated and trimmed to 37 strategies based on experts' 
      opinion. The Multiple criteria decision-making (MCDM) methods were applied in 
      second phase. Five important criteria including cost, time, labor, compliance 
      with law and culture were weighed by Analytic Hierarchy Process (AHP) technique. 
      Then, 37 alternatives have been rated base on the five criteria on the Technique 
      for Order of Preference by Similarity to Ideal Solution (TOPSIS) technique. 
      RESULTS: "Creating integrated Supply chain information system to manage medicines 
      inventory in the country", "Creating and using the databases to predict the 
      shortage of medicines", "Using track and trace system" are alternatives 20th, 
      24th and 25th, which related to supply chain (SC) and information system (IS) 
      dimensions have higher priority in the experts' point of view. The results show 
      IS dimension has 100 percentage of priority; following that policy and supply 
      chain have higher priority, respectively. CONCLUSION: Health systems rely on 
      consistent supplying of pharmaceuticals to support patient care. The results show 
      that information system, policy-making and supply chain are in the top-ranking 
      priorities. Warning system needs to be improved to the advance system via better 
      collaboration with stakeholders, publish precise and explicit national guidelines 
      for drug shortage management, enforce the guidelines, and improve Iran FDA's 
      pharmaceutical market control capability.
FAU - Moosivand, Asiye
AU  - Moosivand A
AD  - Department of Pharmacoeconomics and Pharma Management, Shahid Beheshti University 
      of Medical Sciences, Tehran, Iran.
FAU - Rangchian, Maryam
AU  - Rangchian M
AD  - School of Pharmacy, Hamadan University of Medical Sciences, Hamadan, Iran.
FAU - Zarei, Leila
AU  - Zarei L
AUID- ORCID: 0000-0002-4459-8599
AD  - Health Policy Research Center, Institute of Health, Shiraz University of Medical 
      Sciences, Shiraz, Fars, Iran. leilazarei89@gmail.com.
FAU - Peiravian, Farzad
AU  - Peiravian F
AD  - Department of Pharmacoeconomics and Pharma Management, Shahid Beheshti University 
      of Medical Sciences, Tehran, Iran.
FAU - Mehralian, Gholamhossein
AU  - Mehralian G
AD  - Department of Pharmacoeconomics and Pharma Management, Shahid Beheshti University 
      of Medical Sciences, Tehran, Iran.
FAU - Sharifnia, Hesameddin
AU  - Sharifnia H
AD  - Department of Clinical Epidemiology, Faculty of Medicine, AJA University of 
      Medical Sciences, Tehran, Iran.
LA  - eng
PT  - Journal Article
DEP - 20210402
PL  - England
TA  - J Pharm Health Care Sci
JT  - Journal of pharmaceutical health care and sciences
JID - 101672177
PMC - PMC8017892
OTO - NOTNLM
OT  - Drug shortage
OT  - Iran
OT  - Multi-criteria decision-making
OT  - Pharmaceutical policy
OT  - Supply chain management
COIS- The authors declare that they have no competing interests.
EDAT- 2021/04/03 06:00
MHDA- 2021/04/03 06:01
PMCR- 2021/04/02
CRDT- 2021/04/02 05:42
PHST- 2020/12/27 00:00 [received]
PHST- 2021/03/03 00:00 [accepted]
PHST- 2021/04/02 05:42 [entrez]
PHST- 2021/04/03 06:00 [pubmed]
PHST- 2021/04/03 06:01 [medline]
PHST- 2021/04/02 00:00 [pmc-release]
AID - 10.1186/s40780-021-00200-3 [pii]
AID - 200 [pii]
AID - 10.1186/s40780-021-00200-3 [doi]
PST - epublish
SO  - J Pharm Health Care Sci. 2021 Apr 2;7(1):14. doi: 10.1186/s40780-021-00200-3.