PMID- 33799239 OWN - NLM STAT- MEDLINE DCOM- 20210511 LR - 20210511 IS - 1873-7072 (Electronic) IS - 0308-8146 (Linking) VI - 355 DP - 2021 Sep 1 TI - Hydrophilic carboxyl supported immobilization of UiO-66 for novel bar sorptive extraction of non-steroidal anti-inflammatory drugs in food samples. PG - 129623 LID - S0308-8146(21)00629-4 [pii] LID - 10.1016/j.foodchem.2021.129623 [doi] AB - Herein, the preparation of UiO-66 on frosted glass rod (FGR) was proposed through the coordination interaction of Zr-OH groups and carboxyl sites on FGR. The relative standard deviations (RSDs) of intra-batch and inter-batch were below 8.0% (n = 7). UiO-66-modified FGR (UiO-66@FGR) was applied to the extraction and monitoring of five non-steroidal anti-inflammatory drugs (NSAIDs) by coupling to novel bar sorptive extraction (BSE) with ultra-high performance liquid chromatography (UPLC). Sample volume, stirring rate, extraction time, sample pH value, desorption solvent, and desorption time were investigated. NSAIDs (ketoprofen, flurbiprofen, ibuprofen, naproxen, and diclofenac sodium) were determined at a low limit of detection (0.92 ng/mL) over a wide linear range (10-1500 ng/mL). The developed method was used to analyze NSAIDs in sheep muscle, chicken wing, and milk with recoveries of 80.8%-117.2%, RSDs < 6.5%. Fabricated UiO-66@FGR exhibited excellent reproducibility, stability, and good adsorption property towards NSAIDs in food samples. CI - Copyright (c) 2021 Elsevier Ltd. All rights reserved. FAU - Zhang, Nan AU - Zhang N AD - School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an 710061, China; Shaanxi Engineering Research Center of Cardiovascular Drugs Screening & Analysis, Xi'an 710061, China. FAU - Gao, Yan AU - Gao Y AD - School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an 710061, China; Shaanxi Engineering Research Center of Cardiovascular Drugs Screening & Analysis, Xi'an 710061, China. FAU - Xu, Xianliang AU - Xu X AD - School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an 710061, China; Shaanxi Engineering Research Center of Cardiovascular Drugs Screening & Analysis, Xi'an 710061, China. FAU - Bao, Tao AU - Bao T AD - School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an 710061, China; Shaanxi Engineering Research Center of Cardiovascular Drugs Screening & Analysis, Xi'an 710061, China. Electronic address: baotao@xjtu.edu.cn. FAU - Wang, Sicen AU - Wang S AD - School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an 710061, China; Shaanxi Engineering Research Center of Cardiovascular Drugs Screening & Analysis, Xi'an 710061, China. Electronic address: wangsc@mail.xjtu.edu.cn. LA - eng PT - Journal Article DEP - 20210319 PL - England TA - Food Chem JT - Food chemistry JID - 7702639 RN - 0 (Anti-Inflammatory Agents, Non-Steroidal) SB - IM MH - Animals MH - Anti-Inflammatory Agents, Non-Steroidal/*analysis/chemistry MH - Chickens MH - Chromatography, High Pressure Liquid MH - Hydrophobic and Hydrophilic Interactions MH - Limit of Detection MH - Muscle, Skeletal/chemistry MH - Reproducibility of Results MH - Sheep OTO - NOTNLM OT - Bar sorptive extraction OT - Non-steroidal anti-inflammatory drugs OT - UiO-66 OT - Ultra-high performance liquid chromatography EDAT- 2021/04/03 06:00 MHDA- 2021/05/12 06:00 CRDT- 2021/04/02 20:37 PHST- 2020/06/16 00:00 [received] PHST- 2021/02/03 00:00 [revised] PHST- 2021/03/14 00:00 [accepted] PHST- 2021/04/03 06:00 [pubmed] PHST- 2021/05/12 06:00 [medline] PHST- 2021/04/02 20:37 [entrez] AID - S0308-8146(21)00629-4 [pii] AID - 10.1016/j.foodchem.2021.129623 [doi] PST - ppublish SO - Food Chem. 2021 Sep 1;355:129623. doi: 10.1016/j.foodchem.2021.129623. Epub 2021 Mar 19.