PMID- 33801479
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210408
IS  - 2077-0383 (Print)
IS  - 2077-0383 (Electronic)
IS  - 2077-0383 (Linking)
VI  - 10
IP  - 5
DP  - 2021 Mar 2
TI  - Midterm Survivorship of an Uncemented Hydroxyapatite-Coated Titanium Femoral 
      Component and Clinically Meaningful Outcomes in Patients Older Than 75 Years.
LID - 10.3390/jcm10051019 [doi]
LID - 1019
AB  - PURPOSE: It remains controversial whether cementless femoral components are safe 
      in elderly patients. The aim of this study was (1) to determine the stem survival 
      rate in patients >75 years of age who were treated with an uncemented femoral 
      component and (2) to report clinically significant results on a mid-term 
      follow-up. METHODS: 107 total hip arthroplasties (THA) were retrospectively 
      evaluated in 97 patients over 75 years of age (mean age 78 years, range 75-87) 
      treated with an uncemented femoral stem. The minimum follow-up was five years 
      (mean 6.4 years, range 5-8). Stem survival rates, clinically meaningful outcomes, 
      and incidence of complications were evaluated. RESULTS: Kaplan-Meier survival 
      analysis, with the endpoint revision for any reason, showed a 6.4-year survival 
      rate of 98% (95% CI, 95-99%; 63 hips at risk). The survival rates were comparable 
      for male and female patients (log-rank test, p = 0.58). The modified Harris Hip 
      Score (mHHS) improved from 42.2 (12 to 85) points to 81.1 (22 to 97) points (p < 
      0.0001). Mid-term minimal clinically important difference (MCID), substantial 
      clinical benefit (SCB), and patient acceptable symptomatic state (PASS) were 25, 
      84, and 70, respectively. CONCLUSION: An uncemented stem is a viable option in 
      patients over 75 years with good clinical outcomes and survivorship. 
      Periprosthetic fractures were not a relevant failure mechanism with the stem 
      used.
FAU - Zimmerer, Alexander
AU  - Zimmerer A
AD  - ARCUS Sportklinik, Rastatterstr. 17-19, 75179 Pforzheim, Germany.
AD  - Department of Orthopaedics and Orthopaedic Surgery, University Medicine 
      Greifswald, Ferdinand-Sauerbruch-Strasse, 17475 Greifswald, Germany.
FAU - Navas, Luis
AU  - Navas L
AD  - ARCUS Sportklinik, Rastatterstr. 17-19, 75179 Pforzheim, Germany.
FAU - Kinkel, Stefan
AU  - Kinkel S
AD  - ARCUS Sportklinik, Rastatterstr. 17-19, 75179 Pforzheim, Germany.
FAU - Weiss, Stefan
AU  - Weiss S
AD  - ARCUS Sportklinik, Rastatterstr. 17-19, 75179 Pforzheim, Germany.
FAU - Hauschild, Matthias
AU  - Hauschild M
AD  - ARCUS Sportklinik, Rastatterstr. 17-19, 75179 Pforzheim, Germany.
FAU - Streit, Marcus
AU  - Streit M
AD  - ARCUS Sportklinik, Rastatterstr. 17-19, 75179 Pforzheim, Germany.
LA  - eng
PT  - Journal Article
DEP - 20210302
PL  - Switzerland
TA  - J Clin Med
JT  - Journal of clinical medicine
JID - 101606588
PMC - PMC7958839
OTO - NOTNLM
OT  - Cementless THA
OT  - MCID
OT  - PASS
OT  - SCB
OT  - hip replacement
OT  - octogenarians
OT  - old patient
OT  - survival
COIS- Hauschild received royalties from Link and DePuy. All other authors report no 
      conflict of interests.
EDAT- 2021/04/04 06:00
MHDA- 2021/04/04 06:01
PMCR- 2021/03/02
CRDT- 2021/04/03 01:08
PHST- 2021/01/19 00:00 [received]
PHST- 2021/02/17 00:00 [revised]
PHST- 2021/02/24 00:00 [accepted]
PHST- 2021/04/03 01:08 [entrez]
PHST- 2021/04/04 06:00 [pubmed]
PHST- 2021/04/04 06:01 [medline]
PHST- 2021/03/02 00:00 [pmc-release]
AID - jcm10051019 [pii]
AID - jcm-10-01019 [pii]
AID - 10.3390/jcm10051019 [doi]
PST - epublish
SO  - J Clin Med. 2021 Mar 2;10(5):1019. doi: 10.3390/jcm10051019.