PMID- 33809568
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210413
IS  - 2077-0375 (Print)
IS  - 2077-0375 (Electronic)
IS  - 2077-0375 (Linking)
VI  - 11
IP  - 3
DP  - 2021 Mar 16
TI  - Modalities of Left Ventricle Decompression during VA-ECMO Therapy.
LID - 10.3390/membranes11030209 [doi]
LID - 209
AB  - Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is used to sustain 
      circulatory and respiratory support in patients with severe cardiogenic shock or 
      refractory cardiac arrest. Although VA-ECMO allows adequate perfusion of 
      end-organs, it may have detrimental effects on myocardial recovery. Hemodynamic 
      consequences on the left ventricle, such as the increase of afterload, 
      end-diastolic pressure and volume, can lead to left ventricular (LV) distention, 
      increase of myocardial oxygen consumption and delayed LV function recovery. LV 
      distention occurs in almost 50% of patients supported with VA-ECMO and is 
      associated with an increase in morbidity and mortality. Thus, recognizing, 
      preventing and treating LV distention is key in the management of these patients. 
      In this review, we aim to discuss the pathophysiology of LV distention and to 
      describe the strategies to unload the LV in patients supported with VA-ECMO.
FAU - Ricarte Bratti, Juan Pablo
AU  - Ricarte Bratti JP
AUID- ORCID: 0000-0001-6323-8305
AD  - Montreal Heart Institute, Universite de Montreal, 5000 Belanger Street, Montreal, 
      QC H1T 1C8, Canada.
FAU - Cavayas, Yiorgos Alexandros
AU  - Cavayas YA
AUID- ORCID: 0000-0001-7664-2104
AD  - Montreal Heart Institute, Universite de Montreal, 5000 Belanger Street, Montreal, 
      QC H1T 1C8, Canada.
AD  - Hopital Sacre-Coeur de Montreal, 5400. Gouin Blvd. West, Montreal, QC H4J 1C5, 
      Canada.
FAU - Noly, Pierre Emmanuel
AU  - Noly PE
AUID- ORCID: 0000-0001-6600-1258
AD  - Montreal Heart Institute, Universite de Montreal, 5000 Belanger Street, Montreal, 
      QC H1T 1C8, Canada.
FAU - Serri, Karim
AU  - Serri K
AD  - Montreal Heart Institute, Universite de Montreal, 5000 Belanger Street, Montreal, 
      QC H1T 1C8, Canada.
AD  - Hopital Sacre-Coeur de Montreal, 5400. Gouin Blvd. West, Montreal, QC H4J 1C5, 
      Canada.
FAU - Lamarche, Yoan
AU  - Lamarche Y
AD  - Montreal Heart Institute, Universite de Montreal, 5000 Belanger Street, Montreal, 
      QC H1T 1C8, Canada.
AD  - Hopital Sacre-Coeur de Montreal, 5400. Gouin Blvd. West, Montreal, QC H4J 1C5, 
      Canada.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20210316
PL  - Switzerland
TA  - Membranes (Basel)
JT  - Membranes
JID - 101577807
PMC - PMC8002319
OTO - NOTNLM
OT  - VA-ECMO
OT  - left ventricular assist device
OT  - left ventricular distention
OT  - left ventricular venting
COIS- The authors declare no conflict of interest.
EDAT- 2021/04/04 06:00
MHDA- 2021/04/04 06:01
PMCR- 2021/03/16
CRDT- 2021/04/03 01:33
PHST- 2020/12/30 00:00 [received]
PHST- 2021/03/04 00:00 [revised]
PHST- 2021/03/12 00:00 [accepted]
PHST- 2021/04/03 01:33 [entrez]
PHST- 2021/04/04 06:00 [pubmed]
PHST- 2021/04/04 06:01 [medline]
PHST- 2021/03/16 00:00 [pmc-release]
AID - membranes11030209 [pii]
AID - membranes-11-00209 [pii]
AID - 10.3390/membranes11030209 [doi]
PST - epublish
SO  - Membranes (Basel). 2021 Mar 16;11(3):209. doi: 10.3390/membranes11030209.