PMID- 33810060 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20210408 IS - 1996-1944 (Print) IS - 1996-1944 (Electronic) IS - 1996-1944 (Linking) VI - 14 IP - 6 DP - 2021 Mar 22 TI - Scanning Electron Microscopic Evaluation of the Internal Fit Accuracy of 3D-Printed Biphasic Calcium Phosphate Block: An Ex Vivo Pilot Study. LID - 10.3390/ma14061557 [doi] LID - 1557 AB - The aim of this study was to assess the internal fit accuracy of a three-dimensional (3D)-printed biphasic calcium phosphate (BCP) block compared with a 3D-milled poly methyl methacrylate (PMMA) block by scanning electron microscope (SEM) analysis. In a total of 20 porcine rib bones, two different types of defects having two adjacent walls and a floor were produced: a defect with a flat floor (flat defect; N = 10) and a defect with a concave floor (curved defect; N = 10). Each defect was grafted with either the 3D-printed BCP block or the 3D-milled PMMA block fabricated following the computer aided design. The defects were then cut cross-sectionally and evaluated under the SEM. The extents of internal contact and gap were measured and statistically analyzed (p < 0.05). All blocks in both BCP and PMMA groups were successfully fit to the flat and curved defects. The internal contact ratio was significantly higher in the BCP group (flat defect: 0.47 +/- 0.10; curved defect: 0.29 +/- 0.05) compared with the PMMA group (flat defect: 0.21 +/- 0.13; curved defect: 0.17 +/- 0.04; p < 0.05). The internal gap area was similar between the two groups regardless of the defect types (p > 0.05). The internal fit accuracy of the 3D-printed BCP block was reliable in both the flat and curved defects when compared with the accuracy of the 3D-milled PMMA block. FAU - Jeon, Su-Hee AU - Jeon SH AD - Department of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry, Seoul 03722, Korea. FAU - Song, Young Woo AU - Song YW AUID- ORCID: 0000-0003-1835-5646 AD - Department of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry, Seoul 03722, Korea. FAU - Cha, Jae-Kook AU - Cha JK AD - Department of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry, Seoul 03722, Korea. FAU - Paik, Jeong-Won AU - Paik JW AD - Department of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry, Seoul 03722, Korea. FAU - Han, Sang-Sun AU - Han SS AUID- ORCID: 0000-0003-1775-7862 AD - Department of Oral and Maxillofacial Radiology, Yonsei University College of Dentistry, Seoul 03722, Korea. FAU - Choi, Seong-Ho AU - Choi SH AUID- ORCID: 0000-0001-6704-6124 AD - Department of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry, Seoul 03722, Korea. LA - eng GR - NRF2017R1A2B4002782/National Research Foundation of Korea/ PT - Journal Article DEP - 20210322 PL - Switzerland TA - Materials (Basel) JT - Materials (Basel, Switzerland) JID - 101555929 PMC - PMC8004813 OTO - NOTNLM OT - 3D-milling OT - 3D-printing OT - computer aided design OT - ex vivo study OT - scanning electron microscope COIS- The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results. EDAT- 2021/04/04 06:00 MHDA- 2021/04/04 06:01 PMCR- 2021/03/22 CRDT- 2021/04/03 01:35 PHST- 2021/02/05 00:00 [received] PHST- 2021/03/08 00:00 [revised] PHST- 2021/03/16 00:00 [accepted] PHST- 2021/04/03 01:35 [entrez] PHST- 2021/04/04 06:00 [pubmed] PHST- 2021/04/04 06:01 [medline] PHST- 2021/03/22 00:00 [pmc-release] AID - ma14061557 [pii] AID - materials-14-01557 [pii] AID - 10.3390/ma14061557 [doi] PST - epublish SO - Materials (Basel). 2021 Mar 22;14(6):1557. doi: 10.3390/ma14061557.