PMID- 33810235
OWN - NLM
STAT- MEDLINE
DCOM- 20210426
LR  - 20221207
IS  - 1660-4601 (Electronic)
IS  - 1661-7827 (Print)
IS  - 1660-4601 (Linking)
VI  - 18
IP  - 7
DP  - 2021 Mar 26
TI  - The Combined Effect of Neuromuscular Electrical Stimulation and Insulin Therapy 
      on Glycated Hemoglobin Concentrations, Lipid Profiles and Hemodynamic Parameters 
      in Patients with Type-2-Diabetes and Hemiplegia Related to Ischemic Stroke: A 
      Pilot Study.
LID - 10.3390/ijerph18073433 [doi]
LID - 3433
AB  - Type-2-diabetes mellitus (T2DM) is a global problem of medical, social and 
      economic consequences. Physical activity is a vital therapy in patients with 
      T2DM, but some of them cannot exercise for various reasons. The purpose of our 
      pilot study was to determine whether a combination of neuromuscular 
      electrostimulation (NMES) and insulin therapy could improve the management of 
      T2DM patients with hemiplegia caused by an ischemic stroke. Fifteen immobile 
      patients with T2DM on insulin therapy were enrolled in the study. NMES was 
      applied to their lower limbs for 60 min, 5 days a week, over a period of 12 
      weeks. The intervention caused statistically significant reductions in the blood 
      concentrations of glycated hemoglobin, total cholesterol and low-density 
      cholesterol in the participants. Furthermore, systolic and diastolic blood 
      pressure levels were significantly lower. More randomized clinical trials are 
      needed to accurately measure the effect of NMES on T2DM treatment and to 
      determine whether it can be an alternative for physical activity for immobile 
      patients with T2DM.
FAU - Rubinowicz-Zasada, Maja
AU  - Rubinowicz-Zasada M
AD  - Doctoral School, The Jerzy Kukuczka Academy of Physical Education, 72A Mikolowska 
      Str., 40-065 Katowice, Poland.
AD  - Department of Neurology, Silesian Hospital, 4 Bielska Str, 43-400 Cieszyn, 
      Poland.
FAU - Kucio, Ewa
AU  - Kucio E
AUID- ORCID: 0000-0003-1726-5518
AD  - Institute of Physiotherapy and Health Sciences, The Jerzy Kukuczka Academy of 
      Physical Education, 72A Mikolowska Str., 40-065 Katowice, Poland.
FAU - Polak, Anna
AU  - Polak A
AUID- ORCID: 0000-0003-3445-1099
AD  - Institute of Physiotherapy and Health Sciences, The Jerzy Kukuczka Academy of 
      Physical Education, 72A Mikolowska Str., 40-065 Katowice, Poland.
FAU - Stastny, Petr
AU  - Stastny P
AUID- ORCID: 0000-0003-2841-374X
AD  - Laboratory Physical Training Adaptation, Faculty of Physical Education and Sport, 
      Charles University, Ovocny trh 5, 11636 Prague, Czech Republic.
FAU - Wierzbicki, Krzysztof
AU  - Wierzbicki K
AUID- ORCID: 0000-0001-5019-581X
AD  - Department of Medicine and Dentistry in Zabrze, The Silesian Medical University, 
      2 Traugutta Str., 40-055 Katowice, Poland.
FAU - Krol, Piotr
AU  - Krol P
AUID- ORCID: 0000-0001-7673-4375
AD  - Institute of Physiotherapy and Health Sciences, The Jerzy Kukuczka Academy of 
      Physical Education, 72A Mikolowska Str., 40-065 Katowice, Poland.
FAU - Kucio, Cezary
AU  - Kucio C
AUID- ORCID: 0000-0003-3884-9555
AD  - Institute of Physiotherapy and Health Sciences, The Jerzy Kukuczka Academy of 
      Physical Education, 72A Mikolowska Str., 40-065 Katowice, Poland.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20210326
PL  - Switzerland
TA  - Int J Environ Res Public Health
JT  - International journal of environmental research and public health
JID - 101238455
RN  - 0 (Glycated Hemoglobin A)
RN  - 0 (Insulin)
RN  - 0 (Lipids)
SB  - IM
MH  - *Brain Ischemia
MH  - *Diabetes Mellitus, Type 2/complications/therapy
MH  - Electric Stimulation
MH  - *Electric Stimulation Therapy
MH  - Glycated Hemoglobin
MH  - Hemiplegia
MH  - Hemodynamics
MH  - Humans
MH  - Insulin/therapeutic use
MH  - *Ischemic Stroke
MH  - Lipids
MH  - Pilot Projects
MH  - *Stroke
PMC - PMC8036261
OTO - NOTNLM
OT  - hemiplegia
OT  - ischemic stroke
OT  - neuromuscular electrical stimulation (NMES)
OT  - physical therapy
OT  - type 2 diabetes mellitus (T2DM)
COIS- The authors declare no conflict of interest.
EDAT- 2021/04/04 06:00
MHDA- 2021/04/27 06:00
PMCR- 2021/03/26
CRDT- 2021/04/03 01:35
PHST- 2021/03/14 00:00 [received]
PHST- 2021/03/24 00:00 [accepted]
PHST- 2021/04/03 01:35 [entrez]
PHST- 2021/04/04 06:00 [pubmed]
PHST- 2021/04/27 06:00 [medline]
PHST- 2021/03/26 00:00 [pmc-release]
AID - ijerph18073433 [pii]
AID - ijerph-18-03433 [pii]
AID - 10.3390/ijerph18073433 [doi]
PST - epublish
SO  - Int J Environ Res Public Health. 2021 Mar 26;18(7):3433. doi: 
      10.3390/ijerph18073433.