PMID- 33813814 OWN - NLM STAT- MEDLINE DCOM- 20211015 LR - 20211015 IS - 2233-6087 (Electronic) IS - 2233-6079 (Print) IS - 2233-6079 (Linking) VI - 45 IP - 2 DP - 2021 Mar TI - Diabetes Management in Patients with Heart Failure. PG - 158-172 LID - 10.4093/dmj.2020.0296 [doi] AB - Diabetes and heart failure (HF) are common diseases, each affecting large segments of the world population. Moreover, prevalence rates for both are expected to rise dramatically over coming decades. The high prevalence rates of both diseases and wellrecognized association of diabetes as a risk factor for HF make it inevitable that both diseases co-exist in a large number of patients, complicating their management and increasing the risk of a poor outcome. Management of diabetes has been shown to impact clinical events in patients with HF and there is emerging evidence that agents used to treat diabetes can reduce HF events, even in non-diabetic patients. In this review we summarize the clinical course and treatment of patients with type 2 diabetes mellitus (T2DM) and HF and review the efficacy and safety of pharmacological agents in patients with T2DM at risk for HF and those with established disease. FAU - Shen, Jia AU - Shen J AD - Division of Cardiology, Department of Medicine, University of California San Diego, La Jolla, CA, USA. FAU - Greenberg, Barry H AU - Greenberg BH AD - Division of Cardiology, Department of Medicine, University of California San Diego, La Jolla, CA, USA. LA - eng PT - Journal Article PT - Review DEP - 20210325 PL - Korea (South) TA - Diabetes Metab J JT - Diabetes & metabolism journal JID - 101556588 RN - 0 (Sodium-Glucose Transporter 2 Inhibitors) SB - IM MH - *Diabetes Mellitus, Type 2/complications/drug therapy/epidemiology MH - *Heart Failure/epidemiology/therapy MH - Humans MH - Prevalence MH - Risk Factors MH - *Sodium-Glucose Transporter 2 Inhibitors PMC - PMC8024151 OTO - NOTNLM OT - Diabetes mellitus OT - Heart failure OT - Risk factors OT - Sodium glucose cotransporter 2 inhibitor COIS- CONFLICTS OF INTEREST No potential conflict of interest relevant to this article was reported. EDAT- 2021/04/06 06:00 MHDA- 2021/10/16 06:00 PMCR- 2021/03/01 CRDT- 2021/04/05 03:18 PHST- 2020/12/15 00:00 [received] PHST- 2021/02/25 00:00 [accepted] PHST- 2021/04/05 03:18 [entrez] PHST- 2021/04/06 06:00 [pubmed] PHST- 2021/10/16 06:00 [medline] PHST- 2021/03/01 00:00 [pmc-release] AID - dmj.2020.0296 [pii] AID - dmj-2020-0296 [pii] AID - 10.4093/dmj.2020.0296 [doi] PST - ppublish SO - Diabetes Metab J. 2021 Mar;45(2):158-172. doi: 10.4093/dmj.2020.0296. Epub 2021 Mar 25.