PMID- 33815011 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20210709 IS - 1520-765X (Print) IS - 1554-2815 (Electronic) IS - 1520-765X (Linking) VI - 23 IP - Suppl A DP - 2021 Mar TI - Pump flow setting and assessment of unloading in clinical practice. PG - A23-A26 LID - 10.1093/eurheartj/suab004 [doi] AB - The rationale for mechanical circulatory support (MCS) in cardiogenic shock is to restore cardiac output in selected patients when critically low or in case of refractory cardiac arrest. Furthermore, an MCS device that moves blood from either the left atrium or the left ventricle to the systemic circulation will potentially unload the ventricle. These devices are used alone or in combination with venoarterial extracorporeal membrane oxygenation (VA-ECMO). If a left-sided Impella device is used, it should be run at the highest possible performance level during treatment while avoiding suction events. When combined with VA-ECMO, the Impella device should be run at a lower performance level, ensuring sufficient left ventricular emptying but avoiding suction. Continuous monitoring is pivotal and patients managed outside the catheterization laboratory should be monitored with an arterial line, a central venous catheter, frequent use of pulmonary artery catheters and regular imaging by transthoracic echocardiogram. CI - Published on behalf of the European Society of Cardiology. (c) The Author(s) 2021. FAU - Moller, Jacob Eifer AU - Moller JE AD - Department of Cardiology, Odense University Hospital and Cardiac Intensive Care Unit, Heart Center, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej, DK - 2100 Copenhagen, Denmark. FAU - Hassager, Christian AU - Hassager C AD - Department of Cardiology, Rigshospitalet, Blegdamsvej, DK - 2100 Copenhagen, Denmark. AD - Department of Clinical Medicine, University of Copenhagen, Blegdamsvej, DK - 2100 Copenhagen, Denmark. FAU - Bonello, Laurent AU - Bonello L AD - Department of Cardiology, Aix-Marseille Universite, Cardiac Intensive Care Unit, Assistance Publique-Hopitaux de Marseille, Hopital Nord, Mediterranean Association for Research and Studies in Cardiology (MARS Cardio), 80 Rue Brochier, 13005 Marseille, France. FAU - Delmas, Clement AU - Delmas C AD - Intensive Cardiac Care Unit-Acute and Chronic Mechanical Circulatory Support Team Rangueil University Hospital, Avenue du Professeur Jean Poulhes, 31400 Toulouse, France. FAU - Pappalardo, Federico AU - Pappalardo F AD - Department of Anesthesia and Intensive Care, IRCCS ISMETT, UPMC Italy, Via Ernesto Tricomi, 5, 90127 Palermo, Italy. LA - eng PT - Journal Article DEP - 20210327 PL - England TA - Eur Heart J Suppl JT - European heart journal supplements : journal of the European Society of Cardiology JID - 100886647 PMC - PMC8005883 OTO - NOTNLM OT - Mechanical circulatory support OT - Patient monitoring OT - Unloading EDAT- 2021/04/06 06:00 MHDA- 2021/04/06 06:01 PMCR- 2021/03/27 CRDT- 2021/04/05 05:55 PHST- 2021/04/05 05:55 [entrez] PHST- 2021/04/06 06:00 [pubmed] PHST- 2021/04/06 06:01 [medline] PHST- 2021/03/27 00:00 [pmc-release] AID - suab004 [pii] AID - 10.1093/eurheartj/suab004 [doi] PST - epublish SO - Eur Heart J Suppl. 2021 Mar 27;23(Suppl A):A23-A26. doi: 10.1093/eurheartj/suab004. eCollection 2021 Mar.