PMID- 33815927
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210406
IS  - 2160-200X (Print)
IS  - 2160-200X (Electronic)
IS  - 2160-200X (Linking)
VI  - 11
IP  - 1
DP  - 2021
TI  - Opium Addiction and Correlation with Early and Six-month Outcomes of Presenting 
      with ST Elevation Myocardial Infarction Treated Initially with Thrombolytic 
      Therapy.
PG  - 115-123
AB  - BACKGROUND: Myocardial infarction is one of the most important causes of 
      mortality worldwide. The role of opium addiction in the outcome of myocardial 
      infarction is not known with many unproven beliefs surrounding it. This study was 
      designed to evaluate the effects of opium addiction on in-hospital and six-month 
      outcomes of patients presenting with ST elevation myocardial infarction (STEMI). 
      METHODS: This study was performed on STEMI patients who were initially treated 
      medically in two hospitals without any primary percutaneous coronary intervention 
      (PCI) facility. A total 117 opium addicted patients and 217 non-opium-addicted 
      controls were followed during hospitalization and six months thereafter. The 
      primary endpoint of this study was the in-hospital composite of death, heart 
      failure, recurrent chest pain, and recurrent STEMI. RESULTS: The composite 
      endpoint was not significantly different either in-hospital or after six-month 
      follow up (RR=0.851, 95% CI: 0.578-1.253 and RR=0.899, 95% CI: 0.578-1.253 
      relatively). Multivariate analysis also confirmed that opium addiction was not a 
      predictor of in-hospital or six-month adverse outcome. CONCLUSION: The present 
      study revealed that in-hospital and six-month adverse outcomes in opium addicted 
      patients presenting with STEMI were not significantly different in comparison to 
      patients without any opium addiction.
CI  - AJCD Copyright (c) 2021.
FAU - Mousavi, Mehdi
AU  - Mousavi M
AD  - Clinical Research Development Unit, Shahid Rajaei Educational and Medical Center, 
      Alborz University of Medical Sciences Karaj, Iran.
FAU - Kalhor, Solmaz
AU  - Kalhor S
AD  - Islamic Azad University Shahrood Branch Shahrood, Iran.
FAU - Alizadeh, Mahlaa
AU  - Alizadeh M
AD  - Clinical Research Development Unit, Shahid Rajaei Educational and Medical Center, 
      Alborz University of Medical Sciences Karaj, Iran.
FAU - Movahed, Mohamad Reza
AU  - Movahed MR
AD  - University of Arizona Department of Medicine Tucson, AZ, USA.
LA  - eng
PT  - Journal Article
DEP - 20210215
PL  - United States
TA  - Am J Cardiovasc Dis
JT  - American journal of cardiovascular disease
JID - 101569582
PMC - PMC8012279
OTO - NOTNLM
OT  - Opium
OT  - ST elevation myocardial infarction
OT  - acute coronary syndrome
OT  - addiction
OT  - coronary artery disease
OT  - myocardial infarction
OT  - narcotics
COIS- None.
EDAT- 2021/04/06 06:00
MHDA- 2021/04/06 06:01
PMCR- 2021/02/15
CRDT- 2021/04/05 06:04
PHST- 2020/11/07 00:00 [received]
PHST- 2020/12/29 00:00 [accepted]
PHST- 2021/04/05 06:04 [entrez]
PHST- 2021/04/06 06:00 [pubmed]
PHST- 2021/04/06 06:01 [medline]
PHST- 2021/02/15 00:00 [pmc-release]
PST - epublish
SO  - Am J Cardiovasc Dis. 2021 Feb 15;11(1):115-123. eCollection 2021.