PMID- 33822869 OWN - NLM STAT- MEDLINE DCOM- 20211217 LR - 20220406 IS - 1464-3502 (Electronic) IS - 0735-0414 (Print) IS - 0735-0414 (Linking) VI - 56 IP - 6 DP - 2021 Oct 29 TI - Affect-Based Problem Drinking Risk: The Reciprocal Relationship between Affective Lability and Problem Drinking. PG - 746-753 LID - 10.1093/alcalc/agab024 [doi] AB - AIMS: Negative affect has been implicated in risk for the development of problematic drinking behavior. Furthermore, there is evidence for reciprocal relationships between negative affect and problem drinking, such that engagement in problem drinking also predicts increases in negative affect. However, affective models of risk often fail to consider affective lability-the experience of rapidly changing mood. Although affective lability appears to increase risk for problem drinking, it is unknown if this relationship persists above and beyond other affect-related constructs (e.g. depression, anxiety) and if it is reciprocal in nature. Accordingly, we used a longitudinal survey design to examine (a) if affective lability predicts problem drinking above and beyond depression and anxiety and (b) if affective lability and problem drinking demonstrate a reciprocal relationship. METHODS: First-year college students (n = 358) participated in a three wave longitudinal study. We constructed a structural equation model (SEM) of a random intercept cross-lagged panel model to test our hypotheses. RESULTS: Consistent with our hypotheses, affective lability predicted increases in problem drinking while anxiety and depression did not. Problem drinking and affective lability demonstrated a reciprocal relationship in which increases in one predicted increases in the other at subsequent time points. This relationship was present beyond the predictive effects of anxiety or depression. CONCLUSIONS: Affective lability appears to be an important affect-based predictor of problem drinking, and there may be a reciprocal, risk-enhancing relationship between affective lability and problem drinking.Components of negative affect, such as depression or anxiety, have been shown to predict risk for problem drinking, and vice versa. A less considered construct, affective lability, predicted problem drinking while anxiety and depression did not add any predictive power. Problem drinking and affective lability also appeared to demonstrate a reciprocal relationship. CI - (c) The Author(s) 2021. Medical Council on Alcohol and Oxford University Press. All rights reserved. FAU - Peterson, Sarah J AU - Peterson SJ AD - University of Kentucky, Department of Psychology, 106B Kastle Hall, Lexington, KY 40506, USA. FAU - Atkinson, Emily A AU - Atkinson EA AD - University of Kentucky, Department of Psychology, 106B Kastle Hall, Lexington, KY 40506, USA. FAU - Riley, Elizabeth N AU - Riley EN AD - University of Kentucky, Center for Innovation in Population Health, 364 Healthy Kentucky Building, Lexington, KY 40506, USA. FAU - Davis, Heather A AU - Davis HA AD - University of Chicago, Department of Psychiatry and Behavioral Neuroscience, 5841 S. Maryland Avenue, Chicago, IL 60637, USA. FAU - Smith, Gregory T AU - Smith GT AD - University of Kentucky, Department of Psychology, 106B Kastle Hall, Lexington, KY 40506, USA. LA - eng GR - F31 AA027960/AA/NIAAA NIH HHS/United States GR - T32 MH082761/MH/NIMH NIH HHS/United States GR - T32 AA027488/AA/NIAAA NIH HHS/United States GR - 20-111/Lipman Foundation/ PT - Journal Article PL - England TA - Alcohol Alcohol JT - Alcohol and alcoholism (Oxford, Oxfordshire) JID - 8310684 SB - IM MH - *Affect MH - Alcohol Drinking in College/*psychology MH - Alcoholism/*psychology MH - Anxiety/psychology MH - Depression/psychology MH - Female MH - Humans MH - Latent Class Analysis MH - Longitudinal Studies MH - Male MH - Midwestern United States/epidemiology MH - Students/*psychology/statistics & numerical data MH - Universities MH - Young Adult PMC - PMC8557663 EDAT- 2021/04/07 06:00 MHDA- 2021/12/18 06:00 PMCR- 2022/04/05 CRDT- 2021/04/06 17:23 PHST- 2020/10/15 00:00 [received] PHST- 2021/03/09 00:00 [revised] PHST- 2021/03/09 00:00 [accepted] PHST- 2021/04/07 06:00 [pubmed] PHST- 2021/12/18 06:00 [medline] PHST- 2021/04/06 17:23 [entrez] PHST- 2022/04/05 00:00 [pmc-release] AID - 6210034 [pii] AID - agab024 [pii] AID - 10.1093/alcalc/agab024 [doi] PST - ppublish SO - Alcohol Alcohol. 2021 Oct 29;56(6):746-753. doi: 10.1093/alcalc/agab024.