PMID- 33824815
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210408
IS  - 2168-8184 (Print)
IS  - 2168-8184 (Electronic)
IS  - 2168-8184 (Linking)
VI  - 13
IP  - 3
DP  - 2021 Mar 3
TI  - Ewing's Sarcoma of the Vertebral Body in an Adolescent: A Rare Case Report and 
      Literature Review.
PG  - e13664
LID - 10.7759/cureus.13664 [doi]
LID - e13664
AB  - We report the case of a 14-year-old girl who presented with a one-month history 
      of back pain and bilateral lower limb weakness preceded by constitutional 
      symptoms. She neither had a family history of malignancy nor a previous history 
      of trauma. A series of imaging procedures revealed an aggressive lesion of the 
      T12 vertebra with a large soft-tissue component and intraspinal extension leading 
      to spinal cord compression causing cord edema. She underwent urgent posterior 
      instrumentation and fixation of T9 to T12 vertebrae due to worsening neurological 
      deficits. Adjuvant and neoadjuvant chemotherapy with palliative spinal 
      stabilisation were also performed. Features of the lesion were highly consistent 
      with ES on immunohistochemical study and fluorescence in situ hybridization 
      (FISH) analysis for the EWSR1 gene. Postoperatively, both of her lower limbs 
      improved in power and she benefited from regular physiotherapy.
CI  - Copyright (c) 2021, Goh et al.
FAU - Goh, Teik Chiang
AU  - Goh TC
AD  - Orthopaedics and Traumatology, Hospital Melaka, Melaka City, MYS.
FAU - Bajuri, Mohd Yazid
AU  - Bajuri MY
AD  - Orthopaedics and Traumatology, Universiti Kebangsaan Malaysia Medical Centre, 
      Kuala Lumpur, MYS.
FAU - Yusof, Mohamad Fauzlie
AU  - Yusof MF
AD  - Orthopaedics and Traumatology, Hospital Melaka, Melaka City, MYS.
FAU - Mohd Apandi, Husna
AU  - Mohd Apandi H
AD  - Orthopaedics and Traumatology, Universiti Kebangsaan Malaysia Medical Centre, 
      Kuala Lumpur, MYS.
FAU - Sarifulnizam, Faris Aiman
AU  - Sarifulnizam FA
AD  - Orthopaedics and Traumatology, Universiti Kebangsaan Malaysia Medical Centre, 
      Kuala Lumpur, MYS.
LA  - eng
PT  - Case Reports
DEP - 20210303
PL  - United States
TA  - Cureus
JT  - Cureus
JID - 101596737
PMC - PMC8017601
OTO - NOTNLM
OT  - ewing's sarcoma
OT  - paraplegia
OT  - primary spine tumour
OT  - spinal cord compression
COIS- The authors have declared that no competing interests exist.
EDAT- 2021/04/08 06:00
MHDA- 2021/04/08 06:01
PMCR- 2021/03/03
CRDT- 2021/04/07 06:26
PHST- 2021/04/07 06:26 [entrez]
PHST- 2021/04/08 06:00 [pubmed]
PHST- 2021/04/08 06:01 [medline]
PHST- 2021/03/03 00:00 [pmc-release]
AID - 10.7759/cureus.13664 [doi]
PST - epublish
SO  - Cureus. 2021 Mar 3;13(3):e13664. doi: 10.7759/cureus.13664.