PMID- 33825422
OWN - NLM
STAT- MEDLINE
DCOM- 20210712
LR  - 20210712
IS  - 1897-4279 (Electronic)
IS  - 0022-9032 (Linking)
VI  - 79
IP  - 6
DP  - 2021
TI  - Use of T-wave duration and Tpeak-Tend interval as new prognostic markers for 
      patients treated with cardiac resynchronization therapy.
PG  - 676-683
LID - 10.33963/KP.15919 [doi]
AB  - BACKGROUND: The use of electrocardiography (ECG) is a practical method to 
      evaluate the response to cardiac resynchronization therapy (CRT) implantation, as 
      it is easily performed and saves time. AIM: This study aimed to assess the 
      predictive value of the T-wave duration and Tpeak-Tend (Tp-e) interval following 
      the CRT implantation administered to heart failure patients. METHODS: Sixty-seven 
      patients with left ventricular ejection fraction </=35, New York Heart Association 
      (NYHA) class II-III, ambulatory class IV, normal sinus rhythm, who have complete 
      left bundle branch block on ECG and treated with CRT were included in this study. 
      Patients who have manifested a >/=10% improvement in ejection fraction following 
      CRT implantation, were categorized as "responders", and the remaining patients 
      were categorized as "non-responders". ECGs and echocardiograms were evaluated 
      both six months before and after CRT implantation. RESULTS: The post-CRT QRS 
      duration (P = 0.01), cQT interval (P = 0.005), T-wave (P <0.001), and Tp-e 
      interval (P <0.001) were found to be significantly reduced in the responder group 
      compared to the non-responder group. The receiver operating characteristics curve 
      analyses revealed that the predictive optimal cut-off of the T-wave was <182 ms 
      (P <0.001), and that of the Tp-e interval was <92 ms (P <0.001). CONCLUSIONS: 
      T-wave and Tp-e interval may be independent predictors of a favorable CRT 
      response in heart failure patients.
FAU - Usalp, Songul
AU  - Usalp S
AD  - Department of Cardiology, Sancaktepe Sehit Profesor Ilhan Varank Education and 
      Research Hospital, Istanbul, Turkey.
FAU - Gunduz, Ramazan
AU  - Gunduz R
AD  - Department of Cardiology, Manisa City Hospital, Manisa, Turkey.
LA  - eng
PT  - Journal Article
DEP - 20210520
PL  - Poland
TA  - Kardiol Pol
JT  - Kardiologia polska
JID - 0376352
SB  - IM
MH  - Bundle-Branch Block/therapy
MH  - *Cardiac Resynchronization Therapy
MH  - Electrocardiography
MH  - *Heart Failure/therapy
MH  - Humans
MH  - Prognosis
MH  - Stroke Volume
MH  - Treatment Outcome
MH  - Ventricular Function, Left
OTO - NOTNLM
OT  - T-wave
OT  - Tpeak-Tend interval
OT  - cardiac resynchronization therapy
OT  - electrocardiography
OT  - heart failure
EDAT- 2021/04/08 06:00
MHDA- 2021/07/13 06:00
CRDT- 2021/04/07 09:58
PHST- 2021/05/06 00:00 [received]
PHST- 2021/04/08 06:00 [pubmed]
PHST- 2021/07/13 06:00 [medline]
PHST- 2021/04/07 09:58 [entrez]
AID - VM/OJS/J/82888 [pii]
AID - 10.33963/KP.15919 [doi]
PST - ppublish
SO  - Kardiol Pol. 2021;79(6):676-683. doi: 10.33963/KP.15919. Epub 2021 May 20.