PMID- 33828374 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20240331 IS - 0976-4879 (Print) IS - 0975-7406 (Electronic) IS - 0975-7406 (Linking) VI - 12 IP - Suppl 2 DP - 2020 Nov TI - Medication Adherence Assessment Among Patients with Type 2 Diabetes Mellitus Treated Polytherapy in Indonesian Community Health Center: A Cross Sectional-Study. PG - S758-S762 LID - 10.4103/jpbs.JPBS_257_19 [doi] AB - BACKGROUND: Type 2 diabetes mellitus (T2DM) is a chronic disease where most of the patients usually need polytherapy. This could affect their medication adherence (MA). However, other complex factors may also associate with MA, which are important to identify. AIM: The purpose of this study was to evaluate the MA of patients with T2DM who received polytherapy and to identify other factors that can affect the MA. MATERIALS AND METHODS: This was a cross-sectional study conducted in seven community health centers in Jakarta with HbA(1C) representing their MA level. Poor controlled blood glucose with Hemoglobin A(1C) (HbA(1C)) of >/=7% is indicated to have low MA. All characteristics were collected to identify factors that are potentially associated with low MA. The univariate analysis tests were used to analyze factors that potentially associate with low MA. Multiple logistic regression analysis was performed in the factors to find their relationship with low MA. RESULTS: The study obtained 143 patients with a female dominance (67.8%) and mean +/- standard deviation (SD) age of 59.53 +/- 9.251 years. Approximately 75.5% of the patients had low MA (HbA(1C) >/= 7). Univariate analysis found that duration of T2DM significantly (P = 0.047) related to MA, where patients with T2DM of less than or equal to 5 years tended to have low MA. Logistic regression showed that patients with T2DM less than or equal to 5 years (P = 0.015, odds ratio = 1.206, 95% confidence interval = 1.216-8.014) were associated with low MA. CONCLUSION: Patients with the duration of T2DM less than or equal to 5 years surprisingly were susceptible to have low MA. Low MA was not affected by polytherapy. CI - Copyright: (c) 2020 Journal of Pharmacy and Bioallied Sciences. FAU - Wulandari, Nora AU - Wulandari N AD - Faculty of Pharmacy and Science, University of Muhammadiyah Prof. DR. HAMKA Jl Delima II/IV Islamic Center, Malakasari, Duren Sawit, East Jakarta, Indonesia. FAU - Maifitrianti, Maifitrianti AU - Maifitrianti M AD - Faculty of Pharmacy and Science, University of Muhammadiyah Prof. DR. HAMKA Jl Delima II/IV Islamic Center, Malakasari, Duren Sawit, East Jakarta, Indonesia. FAU - Hasanah, Faridlatul AU - Hasanah F AD - Faculty of Pharmacy and Science, University of Muhammadiyah Prof. DR. HAMKA Jl Delima II/IV Islamic Center, Malakasari, Duren Sawit, East Jakarta, Indonesia. FAU - Atika, Sri AU - Atika S AD - Faculty of Pharmacy and Science, University of Muhammadiyah Prof. DR. HAMKA Jl Delima II/IV Islamic Center, Malakasari, Duren Sawit, East Jakarta, Indonesia. FAU - Dini Putri, Risa AU - Dini Putri R AD - Faculty of Pharmacy and Science, University of Muhammadiyah Prof. DR. HAMKA Jl Delima II/IV Islamic Center, Malakasari, Duren Sawit, East Jakarta, Indonesia. LA - eng PT - Journal Article DEP - 20201105 PL - India TA - J Pharm Bioallied Sci JT - Journal of pharmacy & bioallied sciences JID - 101537209 PMC - PMC8021045 OTO - NOTNLM OT - Medication adherence OT - polytherapy OT - type 2 diabetes mellitus COIS- There are no conflicts of interest. EDAT- 2021/04/09 06:00 MHDA- 2021/04/09 06:01 PMCR- 2020/11/01 CRDT- 2021/04/08 06:24 PHST- 2019/11/04 00:00 [received] PHST- 2020/02/16 00:00 [revised] PHST- 2020/04/01 00:00 [accepted] PHST- 2021/04/08 06:24 [entrez] PHST- 2021/04/09 06:00 [pubmed] PHST- 2021/04/09 06:01 [medline] PHST- 2020/11/01 00:00 [pmc-release] AID - JPBS-12-758 [pii] AID - 10.4103/jpbs.JPBS_257_19 [doi] PST - ppublish SO - J Pharm Bioallied Sci. 2020 Nov;12(Suppl 2):S758-S762. doi: 10.4103/jpbs.JPBS_257_19. Epub 2020 Nov 5.