PMID- 33835267
OWN - NLM
STAT- MEDLINE
DCOM- 20220207
LR  - 20220207
IS  - 1613-7671 (Electronic)
IS  - 0043-5325 (Linking)
VI  - 134
IP  - 1-2
DP  - 2022 Jan
TI  - Psoas muscle index at the time of diagnosis might reflect the prognosis of 
      classical Hodgkin's lymphoma patients.
PG  - 80-82
LID - 10.1007/s00508-021-01850-x [doi]
AB  - We retrospectively investigated clinical and prognostic significance of psoas 
      muscle index (PMI) calculated as total psoas muscle area at L3 vertebra level 
      obtained from baseline computed tomography (CT) scans in 49 newly diagnosed 
      classical Hodgkin's lymphoma (cHL) patients prior to specific treatment. Median 
      PMI was 572.5 mm(2)/m(2) and was significantly higher in males (P < 0.001), 
      patients with higher body mass index (BMI, P < 0.001), absence of extranodal 
      disease (P = 0.037), higher absolute lymphocyte count (P = 0.037), higher 
      hemoglobin (P = 0.010) and lower lactate dehydrogenase (LDH, P = 0.050). There 
      were no significant associations with age, disease subtype, presence of 
      constitutional symptoms, Ann Arbor disease stage, presence of advanced disease or 
      international prognostic score. Patients with lower PMI had significantly worse 
      PFS (hazard ratio [HR] 4.91; P = 0.009). This phenomenon persisted in the 
      multivariate model (HR = 5.09; P = 0.042) adjusted for International Prognostic 
      Score (IPS) and chemotherapy type.
CI  - (c) 2021. Springer-Verlag GmbH Austria, part of Springer Nature.
FAU - Lucijanic, Marko
AU  - Lucijanic M
AD  - Hematology Department, University Hospital Dubrava, Av. Gojka Suska 6, 10000, 
      Zagreb, Croatia. markolucijanic@yahoo.com.
AD  - School of Medicine, University of Zagreb, Zagreb, Croatia. 
      markolucijanic@yahoo.com.
FAU - Huzjan Korunic, Renata
AU  - Huzjan Korunic R
AD  - School of Medicine, University of Zagreb, Zagreb, Croatia.
AD  - Department of Diagnostic and Interventional Radiology, University Hospital 
      Dubrava, Zagreb, Croatia.
FAU - Ivic, Marija
AU  - Ivic M
AD  - Hematology Department, University Hospital Dubrava, Av. Gojka Suska 6, 10000, 
      Zagreb, Croatia.
FAU - Fazlic Dzankic, Amina
AU  - Fazlic Dzankic A
AD  - Hematology Department, General Hospital Sisak, Sisak, Croatia.
FAU - Jonjic, Zeljko
AU  - Jonjic Z
AD  - Hematology Department, University Hospital Dubrava, Av. Gojka Suska 6, 10000, 
      Zagreb, Croatia.
FAU - Mitrovic, Zdravko
AU  - Mitrovic Z
AD  - Hematology Department, University Hospital Dubrava, Av. Gojka Suska 6, 10000, 
      Zagreb, Croatia.
AD  - School of Medicine, University of Zagreb, Zagreb, Croatia.
FAU - Prka, Zeljko
AU  - Prka Z
AD  - Hematology Department, University Hospital Dubrava, Av. Gojka Suska 6, 10000, 
      Zagreb, Croatia.
FAU - Pirsic, Mario
AU  - Pirsic M
AD  - Hematology Department, University Hospital Dubrava, Av. Gojka Suska 6, 10000, 
      Zagreb, Croatia.
FAU - Jaksic, Ozren
AU  - Jaksic O
AD  - Hematology Department, University Hospital Dubrava, Av. Gojka Suska 6, 10000, 
      Zagreb, Croatia.
AD  - School of Medicine, University of Zagreb, Zagreb, Croatia.
FAU - Gacina, Petar
AU  - Gacina P
AD  - Departments of Internal Medicine, Sestre Milosrdnice University Hospital Center, 
      Zagreb, Croatia.
AD  - School of Dental Medicine, University of Zagreb, Zagreb, Croatia.
FAU - Vlasac Glasnovic, Josipa
AU  - Vlasac Glasnovic J
AD  - Hematology Department, University Hospital Dubrava, Av. Gojka Suska 6, 10000, 
      Zagreb, Croatia.
FAU - Pejsa, Vlatko
AU  - Pejsa V
AD  - Hematology Department, University Hospital Dubrava, Av. Gojka Suska 6, 10000, 
      Zagreb, Croatia.
AD  - School of Medicine, University of Zagreb, Zagreb, Croatia.
LA  - eng
PT  - Journal Article
DEP - 20210409
PL  - Austria
TA  - Wien Klin Wochenschr
JT  - Wiener klinische Wochenschrift
JID - 21620870R
SB  - IM
MH  - *Hodgkin Disease/diagnostic imaging/drug therapy
MH  - Humans
MH  - Male
MH  - Prognosis
MH  - Proportional Hazards Models
MH  - *Psoas Muscles/diagnostic imaging
MH  - Retrospective Studies
OTO - NOTNLM
OT  - Lymphoproliferative neoplasm
OT  - Prognostication
OT  - Progression
OT  - Sarcopenia
OT  - Survival
EDAT- 2021/04/10 06:00
MHDA- 2022/02/08 06:00
CRDT- 2021/04/09 12:48
PHST- 2021/02/06 00:00 [received]
PHST- 2021/03/09 00:00 [accepted]
PHST- 2021/04/10 06:00 [pubmed]
PHST- 2022/02/08 06:00 [medline]
PHST- 2021/04/09 12:48 [entrez]
AID - 10.1007/s00508-021-01850-x [pii]
AID - 10.1007/s00508-021-01850-x [doi]
PST - ppublish
SO  - Wien Klin Wochenschr. 2022 Jan;134(1-2):80-82. doi: 10.1007/s00508-021-01850-x. 
      Epub 2021 Apr 9.