PMID- 33837481 OWN - NLM STAT- MEDLINE DCOM- 20211108 LR - 20211108 IS - 1993-0402 (Electronic) IS - 1672-0415 (Linking) VI - 27 IP - 8 DP - 2021 Aug TI - Effectiveness and Safety of Moxibustion Robots on Primary Dysmenorrhea: A Randomized Controlled Pilot Trial. PG - 578-584 LID - 10.1007/s11655-021-3287-8 [doi] AB - OBJECTIVE: To conduct a pilot trial to explore the effectiveness and safety of moxibustion robots in treating primary dysmenorrhea (PD) and evaluate its feasibility in clinic. METHODS: A total of 70 participants with PD were allocated to either moxibustion robot (MR) group (35 cases) or manual moxibustion (MM) group (35 cases) using computer-generated randomization. One acupoint Guanyuan (CV 4) was selected to receive moxa heat stimulation. Two groups of participants were given 3 menstrual cycles of MM and MR treatment respectively (once a day, 5 days a session) and received another 3 menstrual cycles follow-up. The degree of pain was evaluated by short-form McGill pain questionnaire (SF-MPQ) and the symptoms of dysmenorrhea were evaluated by Cox Menstrual Symptom Scale (CMSS). The safety was measured by the occurrence rate of adverse events (AEs), including burns (blisters, red and swollen), itching, bowel changes, menstrual cycle disorder, menorrhagia and fatigue, etc. RESULTS: A total of 62 patients completed the trial, 32 in MR group and 30 in MM group. Compared with baseline, scores of SF-MPQ and CMSS significantly decreased in both groups (P<0.05), and no significant difference was observed between the two groups in the 3rd and 6th menstrual cycles (P>0.05). The total occurrence rate of AEs in MR group was 2.1%, which was significantly lower than MM group (7.2%, P<0.05). CONCLUSIONS: MR has the same effect as MM at SF-MPQ and CMSS in patients with PD. However, MR is safer than MM (Trial registration No. ChiCTR1800018236). CI - (c) 2021. The Chinese Journal of Integrated Traditional and Western Medicine Press and Springer-Verlag GmbH Germany, part of Springer Nature. FAU - Zhang, Han-Rui AU - Zhang HR AD - School of Acupuncture Moxibustion and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, China. AD - Department of Rehabilitation, Chengdu Fifth People's Hospital, Chengdu, 611130, China. FAU - Tu, Hai-Yan AU - Tu HY AD - College of Electrical Engineering, Sichuan University, Chengdu, 610065, China. FAU - Wang, Yu AU - Wang Y AD - Department of Rehabilitation, Chengdu Fifth People's Hospital, Chengdu, 611130, China. FAU - Xia, Shi-Lin AU - Xia SL AD - College of Electrical Engineering, Sichuan University, Chengdu, 610065, China. FAU - Zhao, Guo-You AU - Zhao GY AD - College of Electrical Engineering, Sichuan University, Chengdu, 610065, China. FAU - Yang, Ting AU - Yang T AD - School of Acupuncture Moxibustion and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, China. FAU - Li, Ying-Kun AU - Li YK AD - Department of Acupuncture and Rehabilitation, Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, China. 975470100@qq.com. LA - eng PT - Journal Article PT - Randomized Controlled Trial DEP - 20210410 PL - China TA - Chin J Integr Med JT - Chinese journal of integrative medicine JID - 101181180 SB - IM MH - Acupuncture Points MH - *Dysmenorrhea/therapy MH - Female MH - Humans MH - *Moxibustion MH - Pilot Projects MH - *Robotics OTO - NOTNLM OT - moxibustion robot OT - primary dysmenorrhea OT - randomized controlled pilot trial EDAT- 2021/04/11 06:00 MHDA- 2021/11/09 06:00 CRDT- 2021/04/10 06:01 PHST- 2020/01/23 00:00 [accepted] PHST- 2021/04/11 06:00 [pubmed] PHST- 2021/11/09 06:00 [medline] PHST- 2021/04/10 06:01 [entrez] AID - 10.1007/s11655-021-3287-8 [pii] AID - 10.1007/s11655-021-3287-8 [doi] PST - ppublish SO - Chin J Integr Med. 2021 Aug;27(8):578-584. doi: 10.1007/s11655-021-3287-8. Epub 2021 Apr 10.