PMID- 33842624
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220422
IS  - 2305-5839 (Print)
IS  - 2305-5847 (Electronic)
IS  - 2305-5839 (Linking)
VI  - 9
IP  - 5
DP  - 2021 Mar
TI  - Non-intubated video-assisted thoracic surgery for subxiphoid anterior mediastinal 
      tumor resection.
PG  - 403
LID - 10.21037/atm-20-6125 [doi]
LID - 403
AB  - BACKGROUND: Subxiphoid approach for mediastinal tumor resection was reported to 
      provide a better view and less postoperative pain. Non-intubated video-assisted 
      thoracic surgery (NI-VATS) without muscle relaxant would decrease the possibility 
      of postoperative airway collapse for anterior mediastinal mass operation. Herein, 
      we sought to describe the use of NI-VATS through subxiphoid approach for anterior 
      mediastinal tumor resection. METHODS: In this retrospective cohort study, 
      patients that underwent subxiphoid VATS resection for anterior mediastinal tumor 
      between December 2015 and September 2019 were divided into two groups: NI-VATS 
      and intubated VATS (I-VATS). Intraoperative and postoperative variables were 
      compared. RESULTS: A total of 40 patients were included. Among them, 21 patients 
      received NI-VATS (52.5%) and 19 were treated with I-VATS (47.5%). In total, 
      intraoperative (4/21 vs. 2/19; P=0.446) and postoperative complications (5/21 vs. 
      7/19; P=0.369) were similar between NI-VATS and I-VATS group. The anesthesia time 
      (231.76 vs. 244.71 min; P=0.218), the operation time (152.35 vs. 143.64 min; 
      P=0.980), chest tube duration (1.81 vs. 1.84 days; P=0.08), the total volume 
      (351.95 vs. 348.00 mL; P=0.223), post-operative pain scores (2.79 vs. 2.93, 
      P=0.413), and the length of stay (9.47 vs. 10.57 days; P=0.970) were all 
      comparable between two groups. CONCLUSIONS: NI-VATS for mediastinal tumor 
      resection via subxiphoid approach is a safe and technically feasible option in 
      selected patients, which leads to comparable perioperative clinical outcomes when 
      compared with I-VATS via the subxiphoid approach. This technique could be used as 
      an alteration when intubation is not available.
CI  - 2021 Annals of Translational Medicine. All rights reserved.
FAU - Mao, Yong
AU  - Mao Y
AD  - Department of Cardiothoracic Surgery, Ningbo First Hospital, Ningbo, China.
AD  - Department of Thoracic Surgery and Oncology, the First Affiliated Hospital of 
      Guangzhou Medical University, State Key Laboratory of Respiratory Disease, 
      National Clinical Research Center for Respiratory Disease, Guangzhou Institute of 
      Respiratory Health, Guangzhou, China.
FAU - Liang, Hengrui
AU  - Liang H
AD  - Department of Thoracic Surgery and Oncology, the First Affiliated Hospital of 
      Guangzhou Medical University, State Key Laboratory of Respiratory Disease, 
      National Clinical Research Center for Respiratory Disease, Guangzhou Institute of 
      Respiratory Health, Guangzhou, China.
FAU - Deng, Shiqi
AU  - Deng S
AD  - Department of Anesthesia, Guangzhou Women and Children's Medical Center, 
      Guangzhou Medical University, Guangzhou, China.
FAU - Qiu, Yuan
AU  - Qiu Y
AD  - Department of Thoracic Surgery and Oncology, the First Affiliated Hospital of 
      Guangzhou Medical University, State Key Laboratory of Respiratory Disease, 
      National Clinical Research Center for Respiratory Disease, Guangzhou Institute of 
      Respiratory Health, Guangzhou, China.
FAU - Zhou, Yanran
AU  - Zhou Y
AD  - Department of Anesthesia, the First Affiliated Hospital of Guangzhou Medical 
      University, Guangzhou, China.
FAU - Chen, Hanzhang
AU  - Chen H
AD  - Department of Thoracic Surgery and Oncology, the First Affiliated Hospital of 
      Guangzhou Medical University, State Key Laboratory of Respiratory Disease, 
      National Clinical Research Center for Respiratory Disease, Guangzhou Institute of 
      Respiratory Health, Guangzhou, China.
FAU - Jiang, Long
AU  - Jiang L
AD  - Department of Thoracic Surgery and Oncology, the First Affiliated Hospital of 
      Guangzhou Medical University, State Key Laboratory of Respiratory Disease, 
      National Clinical Research Center for Respiratory Disease, Guangzhou Institute of 
      Respiratory Health, Guangzhou, China.
FAU - He, Jianxing
AU  - He J
AD  - Department of Thoracic Surgery and Oncology, the First Affiliated Hospital of 
      Guangzhou Medical University, State Key Laboratory of Respiratory Disease, 
      National Clinical Research Center for Respiratory Disease, Guangzhou Institute of 
      Respiratory Health, Guangzhou, China.
LA  - eng
PT  - Journal Article
PL  - China
TA  - Ann Transl Med
JT  - Annals of translational medicine
JID - 101617978
PMC - PMC8033331
OTO - NOTNLM
OT  - Non-intubated video-assisted thoracic surgery (NI-VATS)
OT  - mediastinal tumor
OT  - subxiphoid
COIS- Conflicts of Interest: All authors have completed the ICMJE uniform disclosure 
      form (available at http://dx.doi.org/10.21037/atm-20-6125). JH serves as an 
      unpaid Editors-in-Chief of Annals of Translational Medicine. The other authors 
      have no conflicts of interest to declare.
EDAT- 2021/04/13 06:00
MHDA- 2021/04/13 06:01
PMCR- 2021/03/01
CRDT- 2021/04/12 06:25
PHST- 2021/04/12 06:25 [entrez]
PHST- 2021/04/13 06:00 [pubmed]
PHST- 2021/04/13 06:01 [medline]
PHST- 2021/03/01 00:00 [pmc-release]
AID - atm-09-05-403 [pii]
AID - 10.21037/atm-20-6125 [doi]
PST - ppublish
SO  - Ann Transl Med. 2021 Mar;9(5):403. doi: 10.21037/atm-20-6125.