PMID- 33845555 OWN - NLM STAT- MEDLINE DCOM- 20211125 LR - 20211125 IS - 2092-9382 (Electronic) IS - 1011-8942 (Print) IS - 1011-8942 (Linking) VI - 35 IP - 2 DP - 2021 Apr TI - Prevalence and Progression of Stage 0 Macular Hole in Fellow Eyes of Patients with Idiopathic Full-thickness Macular Hole. PG - 107-111 LID - 10.3341/kjo.2020.0078 [doi] AB - PURPOSE: To assess the prevalence and progression of a stage 0 macular hole in the fellow eye of patients with an idiopathic full-thickness macular hole. METHODS: The fellow eyes of 189 patients who underwent idiopathic full-thickness macular hole surgery were examined by biomicroscopy and spectral domain-optical coherence tomography (SD-OCT). A subset of 21 fellow eyes with a stage 0 macular hole was observed. Changes in the macular hole were evaluated by biomicroscopy and SD-OCT for an average of 29 months. RESULTS: Among the 21 eyes, 15 showed no change in perifoveal vitreous detachment (71.4%). Two eyes (9.5%) developed complete vitreofoveal separation, and one of the two developed a separation after progression to stage 1A. Among 21 eyes, 5 (23.8%) developed above stage 1A, and one of the five progressed to stage 1B after five years, which was successfully treated with vitrectomy and gas tamponade. CONCLUSIONS: Perifoveal vitreous detachment in the fellow eye on SD-OCT, defined as a stage 0 macular hole, occurred at an earlier phase than stage 1A macular holes and may progress to an advanced stage. Therefore, patients who undergo macular hole surgery and have a stage 0 macular hole or perifoveal vitreous detachment in the fellow eye should be followed closely. FAU - Chun, Ji Woong AU - Chun JW AD - Barun Eye Clinic, Gwangju, Korea. FAU - Kim, Chang Hwan AU - Kim CH AD - Nune Eye Hospital, Seoul, Korea. FAU - Kim, Ju Young AU - Kim JY AD - Nune Eye Hospital, Seoul, Korea. FAU - Oh, Hyun Sub AU - Oh HS AD - Nune Eye Hospital, Seoul, Korea. FAU - Kim, Soon Hyun AU - Kim SH AD - Nune Eye Hospital, Seoul, Korea. FAU - Kwon, Oh Woong AU - Kwon OW AD - Nune Eye Hospital, Seoul, Korea. FAU - You, Yong Sung AU - You YS AD - Nune Eye Hospital, Seoul, Korea. LA - eng PT - Journal Article DEP - 20210405 PL - Korea (South) TA - Korean J Ophthalmol JT - Korean journal of ophthalmology : KJO JID - 8804513 SB - IM MH - Fovea Centralis MH - Humans MH - Prevalence MH - *Retinal Perforations/diagnosis/epidemiology/surgery MH - Tomography, Optical Coherence MH - Vitreous Body PMC - PMC8046619 OTO - NOTNLM OT - Optical coherence tomography OT - Retinal perforations OT - Vitreous detachment COIS- Conflict of Interest No potential conflict of interest relevant to this article was reported. EDAT- 2021/04/14 06:00 MHDA- 2021/11/26 06:00 PMCR- 2021/04/01 CRDT- 2021/04/13 03:40 PHST- 2020/06/15 00:00 [received] PHST- 2021/02/22 00:00 [accepted] PHST- 2021/04/13 03:40 [entrez] PHST- 2021/04/14 06:00 [pubmed] PHST- 2021/11/26 06:00 [medline] PHST- 2021/04/01 00:00 [pmc-release] AID - kjo.2020.0078 [pii] AID - kjo-2020-0078 [pii] AID - 10.3341/kjo.2020.0078 [doi] PST - ppublish SO - Korean J Ophthalmol. 2021 Apr;35(2):107-111. doi: 10.3341/kjo.2020.0078. Epub 2021 Apr 5.