PMID- 33847085
OWN - NLM
STAT- MEDLINE
DCOM- 20210423
LR  - 20211204
IS  - 1598-6357 (Electronic)
IS  - 1011-8934 (Print)
IS  - 1011-8934 (Linking)
VI  - 36
IP  - 14
DP  - 2021 Apr 12
TI  - Adverse Events in Healthcare Workers after the First Dose of ChAdOx1 nCoV-19 or 
      BNT162b2 mRNA COVID-19 Vaccination: a Single Center Experience.
PG  - e107
LID - 10.3346/jkms.2021.36.e107 [doi]
LID - e107
AB  - Coronavirus disease 2019 vaccinations for healthcare workers (HCWs) have begun in 
      South Korea. To investigate adverse events (AEs) of the first dose of each 
      vaccine, any symptom was collected daily for seven days after vaccination in a 
      tertiary hospital. We found that 1,301 of 1,403 ChAdOx1 nCoV-19 recipients and 38 
      of 80 BNT162b2 recipients reported AEs respectively (90.9% vs. 52.5%): 
      injection-site pain (77.7% vs. 51.2%), myalgia (60.5% vs. 11.2%), fatigue (50.7% 
      vs. 7.5%), headache (47.4% vs. 7.5%), and fever (36.1% vs. 5%; P < 0.001 for 
      all). Young HCWs reported more AEs with ChAdOx1 nCoV-19 than with BNT162b2. No 
      incidences of anaphylaxis were observed. Only one serious AE required 
      hospitalization for serious vomiting, and completely recovered. In conclusion, 
      reported AEs were more common in recipients with ChAdOx1 nCoV-19 than in those 
      with BNT162b2. However, most of the reported AEs were mild to moderate in 
      severity. Sufficient explanation and preparation for expected AEs required to 
      promote widespread vaccination.
CI  - (c) 2021 The Korean Academy of Medical Sciences.
FAU - Kim, Si Ho
AU  - Kim SH
AUID- ORCID: 0000-0001-7763-8940
AD  - Center for Infection Prevention and Control, Samsung Changwon Hospital, Changwon, 
      Korea.
FAU - Wi, Yu Mi
AU  - Wi YM
AUID- ORCID: 0000-0003-3625-3328
AD  - Division of Infectious Diseases, Samsung Changwon Hospital, Sungkyunkwan 
      University, Changwon, Korea.
FAU - Yun, Su Yeon
AU  - Yun SY
AUID- ORCID: 0000-0001-8522-9661
AD  - Center for Infection Prevention and Control, Samsung Changwon Hospital, Changwon, 
      Korea.
FAU - Ryu, Jeong Seon
AU  - Ryu JS
AUID- ORCID: 0000-0003-2766-4483
AD  - Center for Infection Prevention and Control, Samsung Changwon Hospital, Changwon, 
      Korea.
FAU - Shin, Jung Min
AU  - Shin JM
AUID- ORCID: 0000-0002-7766-4871
AD  - Center for Infection Prevention and Control, Samsung Changwon Hospital, Changwon, 
      Korea.
FAU - Lee, Eun Hui
AU  - Lee EH
AUID- ORCID: 0000-0002-3207-4237
AD  - Center for Infection Prevention and Control, Samsung Changwon Hospital, Changwon, 
      Korea.
FAU - Seo, Kyung Hwa
AU  - Seo KH
AUID- ORCID: 0000-0001-6772-3893
AD  - Center for Infection Prevention and Control, Samsung Changwon Hospital, Changwon, 
      Korea.
FAU - Lee, Sung Hee
AU  - Lee SH
AUID- ORCID: 0000-0003-4397-9960
AD  - Center for Infection Prevention and Control, Samsung Changwon Hospital, Changwon, 
      Korea.
FAU - Peck, Kyong Ran
AU  - Peck KR
AUID- ORCID: 0000-0002-7464-9780
AD  - Division of Infectious Diseases, Samsung Medical Center, Sungkyunkwan University 
      School of Medicine, Seoul, Korea. krpeck@skku.edu.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20210412
PL  - Korea (South)
TA  - J Korean Med Sci
JT  - Journal of Korean medical science
JID - 8703518
RN  - 0 (COVID-19 Vaccines)
RN  - B5S3K2V0G8 (ChAdOx1 nCoV-19)
RN  - N38TVC63NU (BNT162 Vaccine)
SB  - IM
MH  - Adult
MH  - BNT162 Vaccine
MH  - COVID-19/*prevention & control
MH  - COVID-19 Vaccines/*adverse effects
MH  - ChAdOx1 nCoV-19
MH  - Female
MH  - *Health Personnel
MH  - Hospitalization
MH  - Humans
MH  - Incidence
MH  - Male
MH  - Middle Aged
MH  - Republic of Korea/epidemiology
MH  - Tertiary Care Centers
MH  - Vaccination/adverse effects
PMC - PMC8042479
OTO - NOTNLM
OT  - Adverse Event
OT  - BNT162b2 mRNA COVID-19 Vaccine
OT  - ChAdOx1 nCoV-19 Vaccine
OT  - Coronavirus Disease 2019
OT  - Vaccine
COIS- The authors have no potential conflicts of interest to declare.
EDAT- 2021/04/14 06:00
MHDA- 2021/04/24 06:00
PMCR- 2021/04/12
CRDT- 2021/04/13 06:47
PHST- 2021/03/23 00:00 [received]
PHST- 2021/04/01 00:00 [accepted]
PHST- 2021/04/13 06:47 [entrez]
PHST- 2021/04/14 06:00 [pubmed]
PHST- 2021/04/24 06:00 [medline]
PHST- 2021/04/12 00:00 [pmc-release]
AID - 36.e107 [pii]
AID - 10.3346/jkms.2021.36.e107 [doi]
PST - epublish
SO  - J Korean Med Sci. 2021 Apr 12;36(14):e107. doi: 10.3346/jkms.2021.36.e107.