PMID- 33848061
OWN - NLM
STAT- MEDLINE
DCOM- 20220228
LR  - 20220228
IS  - 1753-0407 (Electronic)
IS  - 1753-0407 (Linking)
VI  - 13
IP  - 11
DP  - 2021 Nov
TI  - The association of energy and macronutrient intake at dinner vs breakfast with 
      the incidence of type 2 diabetes mellitus in a cohort study: The China Health and 
      Nutrition Survey, 1997-2011.
PG  - 882-892
LID - 10.1111/1753-0407.13185 [doi]
AB  - BACKGROUND: This study aims to investigate the association of energy and 
      macronutrient intake at dinner vs breakfast with the incidence of type 2 diabetes 
      mellitus (T2DM). METHODS: A total of 11 153 adults, including 811 with T2DM, 
      completed a questionnaire about energy and macronutrient intake in the China 
      Health and Nutrition Survey (1997-2011). The differences (Delta) in energy and 
      macronutrient intake between dinner and breakfast (Delta = dinner - breakfast) were 
      categorized into quintiles. Cox proportional hazards regression models were 
      performed to explore the association between Delta and the risk of T2DM and to 
      investigate the change of the risk when 5% total energy or energy provided by 
      macronutrients at dinner was substituted with total energy or energy provided by 
      macronutrients at breakfast by isocaloric substitution models. RESULTS: After 
      adjustment for potential confounders, compared with participants in the lowest 
      quintile, participants in the highest quintile were more likely to develop T2DM 
      (hazard ratio [HR](Deltaenergy) 1.46, 95% CI 1.13-1.87; HR(Deltafat) 1.85, 95% CI 
      1.43-2.41; HR(Deltaprotein) 1.37, 95% CI 1.06-1.78). Isocalorically replacing 5% 
      energy at dinner with energy at breakfast was associated with a 7% lower T2DM 
      risk. Replacing 5% energy provided by fat at dinner with energy provided by 
      carbohydrate, protein, and fat at breakfast was associated with a 9%, 5%, and 7% 
      lower T2DM risk, respectively. Replacing 5% energy provided by protein at dinner 
      with energy provided by carbohydrate or protein at breakfast was associated with 
      a 5% lower T2DM risk. CONCLUSIONS: Higher intake of energy, protein, and fat at 
      dinner than at breakfast increased the risk of T2DM.
CI  - (c) 2021 Ruijin Hospital, Shanghai Jiaotong University School of Medicine and John 
      Wiley & Sons Australia, Ltd.
FAU - Ren, Xiyun
AU  - Ren X
AUID- ORCID: 0000-0003-3198-4535
AD  - National Key Discipline, Department of Nutrition and Food Hygiene, School of 
      Public Health, Harbin Medical University, Harbin, China.
FAU - Yang, Xue
AU  - Yang X
AD  - National Key Discipline, Department of Nutrition and Food Hygiene, School of 
      Public Health, Harbin Medical University, Harbin, China.
FAU - Jiang, Haiyang
AU  - Jiang H
AD  - National Key Discipline, Department of Nutrition and Food Hygiene, School of 
      Public Health, Harbin Medical University, Harbin, China.
FAU - Han, Tianshu
AU  - Han T
AD  - National Key Discipline, Department of Nutrition and Food Hygiene, School of 
      Public Health, Harbin Medical University, Harbin, China.
FAU - Sun, Changhao
AU  - Sun C
AD  - National Key Discipline, Department of Nutrition and Food Hygiene, School of 
      Public Health, Harbin Medical University, Harbin, China.
LA  - eng
GR  - The National Natural Science Foundation (81803227)/Tianshu Han/
GR  - Young Elite Scientists Sponsorship Program by CAST/Tianshu Han/
GR  - National Key R&D Program of China (2017YFC1307401)/Changhao Sun/
PT  - Journal Article
DEP - 20210511
PL  - Australia
TA  - J Diabetes
JT  - Journal of diabetes
JID - 101504326
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Dietary Fats)
RN  - 0 (Dietary Proteins)
SB  - IM
MH  - Adult
MH  - *Breakfast
MH  - Cohort Studies
MH  - Diabetes Mellitus, Type 2/*epidemiology/metabolism/physiopathology
MH  - Dietary Carbohydrates/administration & dosage
MH  - Dietary Fats/administration & dosage
MH  - Dietary Proteins/administration & dosage
MH  - *Eating
MH  - *Energy Intake
MH  - Feeding Behavior
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Male
MH  - *Meals
MH  - Nutrients/*analysis
MH  - Prognosis
MH  - Surveys and Questionnaires
OTO - NOTNLM
OT  - 2型糖尿病。
OT  - dietary substitution model
OT  - energy
OT  - macronutrient
OT  - type 2 diabetes mellitus
OT  - 宏量营养素
OT  - 能量
OT  - 膳食替代模型
EDAT- 2021/04/14 06:00
MHDA- 2022/03/01 06:00
CRDT- 2021/04/13 12:25
PHST- 2021/02/16 00:00 [revised]
PHST- 2020/09/09 00:00 [received]
PHST- 2021/04/09 00:00 [accepted]
PHST- 2021/04/14 06:00 [pubmed]
PHST- 2022/03/01 06:00 [medline]
PHST- 2021/04/13 12:25 [entrez]
AID - 10.1111/1753-0407.13185 [doi]
PST - ppublish
SO  - J Diabetes. 2021 Nov;13(11):882-892. doi: 10.1111/1753-0407.13185. Epub 2021 May 
      11.