PMID- 33849840
OWN - NLM
STAT- MEDLINE
DCOM- 20210415
LR  - 20220531
IS  - 1673-4254 (Print)
IS  - 2663-0842 (Electronic)
IS  - 1673-4254 (Linking)
VI  - 41
IP  - 3
DP  - 2021 Mar 25
TI  - [Association between serum CTRP9 levels and diabetic retinopathy in patients with 
      type 2 diabetes mellitus].
PG  - 459-463
LID - 10.12122/j.issn.1673-4254.2021.03.21 [doi]
AB  - OBJECTIVE: To investigate the relationship between serum C1q tumor necrosis 
      factor-related protein 9 (CTRP9) level and the risk of diabetic retinopathy (DR) 
      in patients with type 2 diabetes mellitus (T2DM). OBJECTIVE: A total of 291 
      patients with T2DM underwent fundus examination, and their serum levels of CTRP9, 
      insulin and adiponectin were measured using enzyme- linked immunosorbent assay. 
      According to results of fundus examination, the patients were divided into DR 
      group and non-DR (NDR) group, and logistic regression was used to analyze the 
      relationship between serum CTRP9 levels and DR in T2DM patients. OBJECTIVE: 
      Compared with those in NDR group, the patients with DR showed significantly 
      increased serum CTRP9 level (P < 0.001) and decreased serum adiponectin level (P 
      < 0.001). Pearson correlation analysis showed that in patients with T2DM 
      complicated by DR, serum CTRP9 levels had a significant positive correlation with 
      DR stage (P < 0.05) and a negative correlation with serum adiponectin level (P < 
      0.001). Multivariate logistic regression analysis showed that with the increase 
      of serum CTRP9 level, the risk of DR is significantly increased in patients with 
      T2DM. OBJECTIVE: In patients with T2DM complicated by DR, an increased serum 
      CTRP9 level suggests a compensatory response to DR.
FAU - Zhou, P
AU  - Zhou P
AD  - Kunshan Chinese Medicine Hospital Affiliated to Nanjing University of Chinese 
      Medicine, Kunshan 215300, China.
AD  - Nanjing University of Chinese Medicine, Nanjing 210029, China.
FAU - Liu, L
AU  - Liu L
AD  - Kunshan Chinese Medicine Hospital Affiliated to Nanjing University of Chinese 
      Medicine, Kunshan 215300, China.
FAU - Gao, W
AU  - Gao W
AD  - Nanjing University of Chinese Medicine, Nanjing 210029, China.
LA  - chi
PT  - Journal Article
PL  - China
TA  - Nan Fang Yi Ke Da Xue Xue Bao
JT  - Nan fang yi ke da xue xue bao = Journal of Southern Medical University
JID - 101266132
RN  - 0 (Adiponectin)
RN  - 0 (C1QTNF9B protein, human)
RN  - 0 (Glycoproteins)
RN  - 0 (Tumor Necrosis Factor Receptor-Associated Peptides and Proteins)
SB  - IM
MH  - Adiponectin
MH  - *Diabetes Mellitus, Type 2/complications
MH  - *Diabetic Retinopathy
MH  - Glycoproteins/metabolism
MH  - Humans
MH  - Tumor Necrosis Factor Receptor-Associated Peptides and Proteins
PMC - PMC8075780
OTO - NOTNLM
OT  - C1q tumor necrosis factor-related protein 9
OT  - diabetes mellitus, type 2
OT  - diabetic retinopathy
EDAT- 2021/04/15 06:00
MHDA- 2021/04/16 06:00
PMCR- 2021/03/20
CRDT- 2021/04/14 05:50
PHST- 2021/04/14 05:50 [entrez]
PHST- 2021/04/15 06:00 [pubmed]
PHST- 2021/04/16 06:00 [medline]
PHST- 2021/03/20 00:00 [pmc-release]
AID - nfykdxxb-41-3-459 [pii]
AID - 10.12122/j.issn.1673-4254.2021.03.21 [doi]
PST - ppublish
SO  - Nan Fang Yi Ke Da Xue Xue Bao. 2021 Mar 25;41(3):459-463. doi: 
      10.12122/j.issn.1673-4254.2021.03.21.