PMID- 33851381 OWN - NLM STAT- MEDLINE DCOM- 20210415 LR - 20210415 IS - 1438-9592 (Electronic) IS - 0044-409X (Linking) VI - 146 IP - 2 DP - 2021 Apr TI - [Update on Endoscopic Therapies for the Treatment of GERD: GERDX, MUSE, EsophyX]. PG - 188-193 LID - 10.1055/a-1333-3751 [doi] AB - Gastroesophageal reflux disease (GERD) has been a problem for patients throughout in recent decades worldwide and its prevalence is increasing. Until 20 years ago, the established treatments were the proton pump inhibitors (PPI) and varieties of laparoscopic fundoplication (LF). Increasing experience with endoscopy and knowledge of the oesophagogastric junction (EGJ) has led to new options in the treatment of GERD. However, promising short term effects have been found with radiofrequency ablation (RFA, Stretta device), endoscopic mucosal resection (ARMS) for induction of scar tissue at the lower oesophageal sphincter (LES) and endoscopic suture devices like GERDX, MUSE and EsophyX to reconstruct the flap valve at the EGJ. Long-term follow-up data and randomised controlled studies in comparison to LF are still rare. CI - Thieme. All rights reserved. FAU - Tschoner, Andreas AU - Tschoner A AD - Abteilung fur Allgemein-, Viszeral-, Gefass- und Thoraxchirurgie, Ordensklinikum Linz, Barmherzige Schwestern Hospital, Osterreich. LA - ger PT - Journal Article TT - Aktueller Stand bei den endoskopischen Therapieverfahren der GERD (Endoplikation): GERDX, MUSE, EsophyX. DEP - 20210413 PL - Germany TA - Zentralbl Chir JT - Zentralblatt fur Chirurgie JID - 0413645 RN - 0 (Proton Pump Inhibitors) RN - F5TD010360 (Alprostadil) SB - IM MH - *Alprostadil MH - Esophageal Sphincter, Lower/surgery MH - Fundoplication MH - *Gastroesophageal Reflux/surgery MH - Humans MH - Proton Pump Inhibitors MH - Treatment Outcome COIS- Die Autorinnen/Autoren geben an, dass kein Interessenkonflikt besteht. EDAT- 2021/04/15 06:00 MHDA- 2021/04/16 06:00 CRDT- 2021/04/14 06:45 PHST- 2021/04/14 06:45 [entrez] PHST- 2021/04/15 06:00 [pubmed] PHST- 2021/04/16 06:00 [medline] AID - 10.1055/a-1333-3751 [doi] PST - ppublish SO - Zentralbl Chir. 2021 Apr;146(2):188-193. doi: 10.1055/a-1333-3751. Epub 2021 Apr 13.