PMID- 33860805 OWN - NLM STAT- MEDLINE DCOM- 20211207 LR - 20220428 IS - 1615-6692 (Electronic) IS - 0340-9937 (Print) IS - 0340-9937 (Linking) VI - 46 IP - 6 DP - 2021 Dec TI - [Perioprocedural mortality after ICD implantation]. PG - 581-588 LID - 10.1007/s00059-021-05033-2 [doi] AB - BACKGROUND: Implantable cardioverter defibrillators (ICD) represent an established treatment in preventing sudden cardiac death in patients with indications for primary or secondary prophylaxis. As for all complex surgical procedures there remains a risk for the occurrence of complications including death also for ICD implantation. The aim of the present study was to analyze the procedure-related mortality in patients after ICD implantation using the data from the obligatory quality assurance program in North-Rhine/Westphalia. METHODS: Data of all 18,625 patients from the quality assurance datasets who underwent ICD implantation in the years 2010-2012 were analyzed. RESULTS: During the in-hospital stay 118 patients (0.6%) died after ICD implantation. Patients > 80 years old had a higher mortality (1.9% vs. 0.5% in patients < 80 years old, p < 0.001) as well as women (0.95% vs. 0.54% in men, p = 0.004) and patients with higher New York Heart Association (NYHA) class (0.3% for NYHA II, 0.7% for NYHA III, 3.4% for NYHA IV, p < 0.001 for all comparisons). The presence of diabetes mellitus (23% of the collective) did not influence the perioperative mortality, whereas renal failure requiring dialysis showed a significantly increased mortality (p < 0.001 compared to patients with creatinine  1.5 mg/dl not requiring dialysis). Patients with indications for ICD secondary prophylaxis had a significantly higher mortality (1.2% vs. 0.4%, p < 0.001), which increased from 0.6% to 3.7% (p < 0.001) with the occurrence of complications. CONCLUSION: The procedure-related mortality after ICD implantation is increased in patients over 80 years of age, higher NYHA class, patients requiring dialysis, in secondary prevention indications and after the occurrence of perioperative complications. CI - (c) 2021. The Author(s). FAU - Bogossian, Harilaos AU - Bogossian H AUID- ORCID: 0000-0003-4206-630X AD - Klinik fur Kardiologie und Rhythmologie, Ev. Krankenhaus Hagen, Brusebrinkstr. 20, 58135, Hagen, Deutschland. bogossianh@esv.de. AD - Universitat Witten/Herdecke, Witten, Deutschland. bogossianh@esv.de. FAU - Panteloglou, Dimitrios AU - Panteloglou D AD - Klinik fur Kardiologie, Elektrophysiologie und Angiologie, Klinikum Ludenscheid, Ludenscheid, Deutschland. FAU - Karosiene, Zana AU - Karosiene Z AD - Klinik fur Kardiologie, Elektrophysiologie und Angiologie, Klinikum Ludenscheid, Ludenscheid, Deutschland. FAU - Macher-Heidrich, Susanne AU - Macher-Heidrich S AD - Arztekammer Nordrhein, Dusseldorf, Deutschland. FAU - Adomeit, Heinz Jurgen AU - Adomeit HJ AD - Arztekammer Westfalen-Lippe, Munster, Deutschland. FAU - Lemke, Bernd AU - Lemke B AD - Klinik fur Kardiologie, Elektrophysiologie und Angiologie, Klinikum Ludenscheid, Ludenscheid, Deutschland. FAU - Israel, Carsten W AU - Israel CW AD - Klinik fur Kardiologie, Evangelisches Klinikum Bethel, Bielefeld, Deutschland. LA - ger PT - Journal Article TT - Peripoperative Mortalitat nach ICD-Implantation. DEP - 20210416 PL - Germany TA - Herz JT - Herz JID - 7801231 SB - IM MH - Aged MH - Aged, 80 and over MH - Death, Sudden, Cardiac/epidemiology/prevention & control MH - *Defibrillators, Implantable MH - Female MH - *Heart Failure MH - Humans MH - Male MH - Primary Prevention MH - Risk Factors PMC - PMC8642318 OTO - NOTNLM OT - Complications OT - Defibrillators OT - Quality assurance OT - Risk factors OT - Surgery EDAT- 2021/04/17 06:00 MHDA- 2021/12/15 06:00 PMCR- 2021/04/16 CRDT- 2021/04/16 08:43 PHST- 2020/12/19 00:00 [received] PHST- 2021/03/16 00:00 [accepted] PHST- 2021/03/02 00:00 [revised] PHST- 2021/04/17 06:00 [pubmed] PHST- 2021/12/15 06:00 [medline] PHST- 2021/04/16 08:43 [entrez] PHST- 2021/04/16 00:00 [pmc-release] AID - 10.1007/s00059-021-05033-2 [pii] AID - 5033 [pii] AID - 10.1007/s00059-021-05033-2 [doi] PST - ppublish SO - Herz. 2021 Dec;46(6):581-588. doi: 10.1007/s00059-021-05033-2. Epub 2021 Apr 16.