PMID- 33868419
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220422
IS  - 1734-9338 (Print)
IS  - 1897-4295 (Electronic)
IS  - 1734-9338 (Linking)
VI  - 17
IP  - 1
DP  - 2021 Mar
TI  - Characterization and long-term outcomes of patients with myocarditis: a 
      retrospective observational study.
PG  - 60-67
LID - 10.5114/aic.2021.104770 [doi]
AB  - INTRODUCTION: There is limited data on the long-term follow-up of patients with 
      myocarditis. AIM: To investigate the long-term follow-up of patients with 
      myocarditis. MATERIAL AND METHODS: We performed a retrospective observational 
      analysis on the clinical long-term outcomes of patients with myocarditis over a 
      10-year period. The primary outcome was mortality. We identified risk factors for 
      mortality and adverse clinical outcomes. We also compared the characteristics and 
      outcomes of patients presenting with fulminant myocarditis to those presenting 
      with non-fulminant myocarditis. RESULTS: Between May 2004 and December 2014, 203 
      patients with myocarditis or perimyocarditis were admitted to our center. Most 
      patients were male (87.7%) with a median age at presentation of 33 years 
      (interquartile range: 25.4-38.9). The median follow-up period was 56.9 months 
      (interquartile range 25.3-87.3 months), during which the overall mortality was 
      4.4% (9 patients). Fifteen patients presented with fulminant myocarditis. After 
      multivariable analysis, older age (HR = 1.11, 95% CI: 1.05-1.16, p < 0.001) and a 
      poorer New York Heart Association (NYHA) function class (HR = 4.6, 95% CI: 
      1.18-18, p = 0.028) were found to be independently associated with a higher risk 
      of mortality, whereas higher albumin levels at presentation (HR = 0.2, 95% CI: 
      0.07-0.56, p = 0.002) were associated with decreased mortality. The group 
      presenting with fulminant myocarditis had a more severe course of disease and a 
      higher in-hospital mortality (13.3% vs. 0%, p = 0.005). CONCLUSIONS: The overall 
      prognosis of patients with myocarditis is good - in terms of both survival and 
      recovery without residual left ventricular dysfunction.
CI  - Copyright: (c) 2021 Termedia Sp. z o. o.
FAU - Grossman, Shelly Meron
AU  - Grossman SM
AD  - Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
FAU - Pravda, Nili Schamroth
AU  - Pravda NS
AD  - Department of Cardiology, Rabin Medical Center Country, Petah Tikva, Israel.
FAU - Orvin, Katia
AU  - Orvin K
AD  - Department of Cardiology, Rabin Medical Center Country, Petah Tikva, Israel.
FAU - Hamdan, Ashraf
AU  - Hamdan A
AD  - Department of Cardiology, Rabin Medical Center Country, Petah Tikva, Israel.
FAU - Vaturi, Mordehay
AU  - Vaturi M
AD  - Department of Cardiology, Rabin Medical Center Country, Petah Tikva, Israel.
FAU - Bengal, Tuvia
AU  - Bengal T
AD  - Department of Cardiology, Rabin Medical Center Country, Petah Tikva, Israel.
FAU - Kornowski, Ran
AU  - Kornowski R
AD  - Department of Cardiology, Rabin Medical Center Country, Petah Tikva, Israel.
FAU - Weissler-Snir, Adaya
AU  - Weissler-Snir A
AD  - Hartford HealthCare Heart and Vascular Institute, University of Connecticut, CT, 
      USA.
LA  - eng
PT  - Journal Article
DEP - 20210327
PL  - Poland
TA  - Postepy Kardiol Interwencyjnej
JT  - Postepy w kardiologii interwencyjnej = Advances in interventional cardiology
JID - 101272671
PMC - PMC8039934
OTO - NOTNLM
OT  - fulminant
OT  - myocarditis
OT  - outcomes
COIS- The authors declare no conflict of interest.
EDAT- 2021/04/20 06:00
MHDA- 2021/04/20 06:01
PMCR- 2021/03/01
CRDT- 2021/04/19 06:22
PHST- 2020/10/31 00:00 [received]
PHST- 2020/11/30 00:00 [accepted]
PHST- 2021/04/19 06:22 [entrez]
PHST- 2021/04/20 06:00 [pubmed]
PHST- 2021/04/20 06:01 [medline]
PHST- 2021/03/01 00:00 [pmc-release]
AID - 43639 [pii]
AID - 10.5114/aic.2021.104770 [doi]
PST - ppublish
SO  - Postepy Kardiol Interwencyjnej. 2021 Mar;17(1):60-67. doi: 
      10.5114/aic.2021.104770. Epub 2021 Mar 27.