PMID- 33871222 OWN - NLM STAT- MEDLINE DCOM- 20220628 LR - 20220628 IS - 2724-5365 (Electronic) IS - 2724-5985 (Linking) VI - 68 IP - 2 DP - 2022 Jun TI - Safety issues in endoscopy ultrasound-guided interventions using lumen apposing metal stents. PG - 177-185 LID - 10.23736/S2724-5985.21.02862-X [doi] AB - Lumen-apposing metal stents (LAMS) are recently introduced devices that allow to create anastomoses. The indications for LAMS placement are increasing and currently these stents can be used in multiple clinical situations such as endoscopic drainage of pancreatic fluid collections (PFCs), endoscopic ultrasound-guided choledochoduodenostomy (EUS-CDS), endoscopic ultrasound gallbladder drainage (EUS-GBD), endoscopic ultrasound gastrojejunostomy (EUS-GJ). Since their introduction, they have revealed to allow a higher rate of technical and clinical success, and potentially lower risk of adverse events (AEs) compared with previously available devices. Despite ongoing innovation, any advanced intervention carries risks of AEs. These AEs may occur during the deployment or can be delayed because of the consequent effects of the procedure and/or stent itself. This review represents an overview of current indications, technical and clinical results, with an extensive focus on safety issues related to placement and on long-term indwelling related ones. FAU - Auriemma, Francesco AU - Auriemma F AD - Digestive Endoscopy Unit, Humanitas Mater Domini, Castellanza, Varese, Italy. FAU - Fugazza, Alessandro AU - Fugazza A AD - Digestive Endoscopy Unit, Division of Gastroenterology, Humanitas Clinical and Research Center - IRCCS, Rozzano, Milan, Italy. AD - Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy. FAU - Colombo, Matteo AU - Colombo M AD - Digestive Endoscopy Unit, Division of Gastroenterology, Humanitas Clinical and Research Center - IRCCS, Rozzano, Milan, Italy. AD - Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy. FAU - Spadaccini, Marco AU - Spadaccini M AD - Digestive Endoscopy Unit, Division of Gastroenterology, Humanitas Clinical and Research Center - IRCCS, Rozzano, Milan, Italy. AD - Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy. FAU - Repici, Alessandro AU - Repici A AD - Digestive Endoscopy Unit, Division of Gastroenterology, Humanitas Clinical and Research Center - IRCCS, Rozzano, Milan, Italy. AD - Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy. FAU - Anderloni, Andrea AU - Anderloni A AD - Digestive Endoscopy Unit, Division of Gastroenterology, Humanitas Clinical and Research Center - IRCCS, Rozzano, Milan, Italy - andrea.anderloni@humanitas.it. AD - Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy. LA - eng PT - Journal Article PT - Review DEP - 20210419 PL - Italy TA - Minerva Gastroenterol (Torino) JT - Minerva gastroenterology JID - 101777280 SB - IM MH - Drainage/adverse effects/methods MH - Endoscopy/methods MH - *Endosonography/methods MH - Humans MH - *Pancreatic Diseases MH - Stents/adverse effects MH - Ultrasonography, Interventional EDAT- 2021/04/20 06:00 MHDA- 2022/06/29 06:00 CRDT- 2021/04/19 09:49 PHST- 2021/04/20 06:00 [pubmed] PHST- 2022/06/29 06:00 [medline] PHST- 2021/04/19 09:49 [entrez] AID - S2724-5985.21.02862-X [pii] AID - 10.23736/S2724-5985.21.02862-X [doi] PST - ppublish SO - Minerva Gastroenterol (Torino). 2022 Jun;68(2):177-185. doi: 10.23736/S2724-5985.21.02862-X. Epub 2021 Apr 19.