PMID- 33886713 OWN - NLM STAT- MEDLINE DCOM- 20210524 LR - 20231111 IS - 1678-4170 (Electronic) IS - 0066-782X (Print) IS - 0066-782X (Linking) VI - 116 IP - 4 DP - 2021 Apr TI - Access to Reperfusion Therapy and Mortality in Women with ST-Segment-Elevation Myocardial Infarction: VICTIM Register. PG - 695-703 LID - S0066-782X2021000500695 [pii] LID - 10.36660/abc.20190468 [doi] AB - BACKGROUND: Myocardial reperfusion is a fundamental part of the treatment for ST elevation myocardial infarction (STEMI) and is responsible for reducing morbidity and mortality in affected patients. However, reperfusion rates are usually lower and mortality rates higher in women compared to men. OBJECTIVES: To evaluate the prevalence of the use of reperfusion therapies among women and men with STEMI in hospitals where percutaneous coronary intervention (PCI) is available in the state of Sergipe. METHODS: This is a cross-sectional study that used data from the VICTIM Register. Patients diagnosed with STEMI admitted to the four hospitals (one public and three private) where PCI is available in the state of Sergipe were evaluated, from December 2014 to June 2018. A multivariate analysis with adjusted model using mortality as a dependent variable was made. In all analyses, the level of significance adopted was 5% (p < 0.05). RESULTS: A total of 878 volunteers with a confirmed diagnosis of STEMI, of which 33.4% were women, were included in the study. Only 53.3% of the patients underwent myocardial reperfusion (134 women versus 334 men). Fibrinolysis was performed only in 2.3% of all patients (1.7% of women versus 2.6% of men; p = 0.422). The rate of primary PCI was lower (44% versus 54.5%; p = 0.003) and hospital mortality was higher (16.1% versus 6.7%; p < 0.001) in women than in men. CONCLUSION: Women have significantly lower rates of primary PCI and higher hospital mortality. Reperfusion rates were low in both sexes and there was a clear underutilization of thrombolytic agents. FAU - Oliveira, Jussiely Cunha AU - Oliveira JC AUID- ORCID: 0000-0001-6782-8994 AD - Universidade Federal de Sergipe - Nucleo de Pos-Graduacao em Ciencias da Saude, Sao Cristovao, SE - Brasil. AD - Universidade Federal de Sergipe - Nucleo de Pos-graduacao em Enfermagem, Sao Cristovao, SE - Brasil. FAU - Barros, Mayse Pereira Souza AU - Barros MPS AD - Universidade Federal de Sergipe - Medicina, Sao Cristovao, SE - Brasil. FAU - Barreto, Ikaro Daniel de Carvalho AU - Barreto IDC AUID- ORCID: 0000-0001-7253-806X AD - Universidade Federal Rural de Pernambuco - Nucleo de Pos-graduacao em biometria e estatistica aplicada, Recife, PE - Brasil. FAU - Silva Filho, Rubens Cruz AU - Silva Filho RC AD - Universidade Federal de Sergipe - Medicina, Sao Cristovao, SE - Brasil. FAU - Andrade, Volfanio Araujo AU - Andrade VA AUID- ORCID: 0000-0003-1358-0406 AD - Universidade Federal de Sergipe - Medicina, Sao Cristovao, SE - Brasil. FAU - Oliveira, Andre de Melo AU - Oliveira AM AD - Universidade Federal de Sergipe - Medicina, Sao Cristovao, SE - Brasil. FAU - Lima, Ticiane Clair Remacre Munareto AU - Lima TCRM AUID- ORCID: 0000-0002-8022-3727 AD - Universidade Federal de Sergipe - Nucleo de Pos-Graduacao em Ciencias da Saude, Sao Cristovao, SE - Brasil. FAU - Oliveira, Jeferson Cunha AU - Oliveira JC AUID- ORCID: 0000-0002-3578-6379 AD - Universidade Federal de Sergipe - Nucleo de Pos-Graduacao em Ciencias da Saude, Sao Cristovao, SE - Brasil. AD - Hospital Primavera, Aracaju, SE - Brasil. FAU - Arcelino, Larissa Andreline Maia AU - Arcelino LAM AD - Universidade Federal de Sergipe - Nucleo de Pos-Graduacao em Ciencias da Saude, Sao Cristovao, SE - Brasil. AD - Hospital Universitario da Universidade Federal de Sergipe (HU-UFS), Aracaju, SE - Brasil. FAU - Oliveira, Lais Costa Souza AU - Oliveira LCS AD - Universidade Federal de Sergipe - Nucleo de Pos-Graduacao em Ciencias da Saude, Sao Cristovao, SE - Brasil. AD - Hospital Primavera, Aracaju, SE - Brasil. FAU - Santana-Santos, Eduesley AU - Santana-Santos E AUID- ORCID: 0000-0001-8545-5677 AD - Universidade Federal de Sergipe - Nucleo de Pos-graduacao em Enfermagem, Sao Cristovao, SE - Brasil. FAU - Almeida-Santos, Marcos Antonio AU - Almeida-Santos MA AD - Programa de Pos-graduacao em Saude e Ambiente da Universidade Tiradentes, Aracaju, SE - Brasil. FAU - Sousa, Antonio Carlos AU - Sousa AC AUID- ORCID: 0000-0002-4158-9726 AD - Universidade Federal de Sergipe - Nucleo de Pos-Graduacao em Ciencias da Saude, Sao Cristovao, SE - Brasil. AD - Universidade Federal de Sergipe - Medicina, Sao Cristovao, SE - Brasil. AD - Fundacao Sao Lucas - Centro de Ensino e Pesquisa, Aracaju, SE - Brasil. AD - Universidade Federal de Sergipe - Divisao de Cardiologia do Hospital Universitario, Sao Cristovao, SE - Brasil. FAU - Barreto Filho, Jose Augusto Soares AU - Barreto Filho JAS AUID- ORCID: 0000-0002-4884-3379 AD - Universidade Federal de Sergipe - Nucleo de Pos-Graduacao em Ciencias da Saude, Sao Cristovao, SE - Brasil. AD - Universidade Federal de Sergipe - Medicina, Sao Cristovao, SE - Brasil. AD - Fundacao Sao Lucas - Centro de Ensino e Pesquisa, Aracaju, SE - Brasil. LA - eng LA - por PT - Journal Article PT - Research Support, Non-U.S. Gov't TT - Acesso a Terapia de Reperfusao e Mortalidade em Mulheres com Infarto Agudo do Miocardio com Supradesnivelamento do Segmento ST: Registro VICTIM. PL - Brazil TA - Arq Bras Cardiol JT - Arquivos brasileiros de cardiologia JID - 0421031 SB - IM CIN - Arq Bras Cardiol. 2021 Apr;116(4):704-705. PMID: 33886714 MH - Brazil MH - Cross-Sectional Studies MH - Female MH - Hospital Mortality MH - Humans MH - Male MH - Myocardial Reperfusion MH - *Percutaneous Coronary Intervention MH - *ST Elevation Myocardial Infarction/surgery MH - Thrombolytic Therapy MH - Treatment Outcome PMC - PMC8121383 OAB - BACKGROUND: Myocardial reperfusion is a fundamental part of the treatment for ST elevation myocardial infarction (STEMI) and is responsible for reducing morbidity and mortality in affected patients. However, reperfusion rates are usually lower and mortality rates higher in women compared to men. OBJECTIVES: To evaluate the prevalence of the use of reperfusion therapies among women and men with STEMI in hospitals where percutaneous coronary intervention (PCI) is available in the state of Sergipe. METHODS: This is a cross-sectional study that used data from the VICTIM Register. Patients diagnosed with STEMI admitted to the four hospitals (one public and three private) where PCI is available in the state of Sergipe were evaluated, from December 2014 to June 2018. A multivariate analysis with adjusted model using mortality as a dependent variable was made. In all analyses, the level of significance adopted was 5% (p < 0.05). RESULTS: A total of 878 volunteers with a confirmed diagnosis of STEMI, of which 33.4% were women, were included in the study. Only 53.3% of the patients underwent myocardial reperfusion (134 women versus 334 men). Fibrinolysis was performed only in 2.3% of all patients (1.7% of women versus 2.6% of men; p = 0.422). The rate of primary PCI was lower (44% versus 54.5%; p = 0.003) and hospital mortality was higher (16.1% versus 6.7%; p < 0.001) in women than in men. CONCLUSION: Women have significantly lower rates of primary PCI and higher hospital mortality. Reperfusion rates were low in both sexes and there was a clear underutilization of thrombolytic agents. OABL- eng COIS- Potencial conflito de interesses Declaro nao haver conflito de interesses pertinentes. EDAT- 2021/04/23 06:00 MHDA- 2021/05/25 06:00 PMCR- 2021/04/08 CRDT- 2021/04/22 17:34 PHST- 2019/07/15 00:00 [received] PHST- 2020/03/16 00:00 [accepted] PHST- 2021/04/22 17:34 [entrez] PHST- 2021/04/23 06:00 [pubmed] PHST- 2021/05/25 06:00 [medline] PHST- 2021/04/08 00:00 [pmc-release] AID - S0066-782X2021000500695 [pii] AID - abc.20190468 [pii] AID - 10.36660/abc.20190468 [doi] PST - ppublish SO - Arq Bras Cardiol. 2021 Apr;116(4):695-703. doi: 10.36660/abc.20190468.