PMID- 33887808
OWN - NLM
STAT- Publisher
LR  - 20240222
IS  - 1096-9888 (Electronic)
IS  - 1076-5174 (Linking)
VI  - 56
IP  - 5
DP  - 2021 Apr 3
TI  - Development and optimization of a quantitative analysis of main odorants causing 
      off flavours in cork stoppers using headspace solid-phase microextraction gas 
      chromatography tandem mass spectrometry.
PG  - e4728
LID - 10.1002/jms.4728 [doi]
AB  - A simple and sensitive method was developed and validated to simultaneously 
      separate and determine the 2-Methoxy-3,5-dimethylpyrazine, 
      2-Isopropyl-3-methoxypyrazine, guaiacol, 2-Isobutyl-3-methoxypyrazine, 
      2-Methylisoborneol, geosmin, 2,4,6-Trichloroanisole, 2,3,4,6-Tetrachloroanisole, 
      2,4,6-Tribromoanisole and Pentachloroanisole in cork stoppers via headspace 
      solid-phase microextraction (HS-SPME) coupled with gas chromatography tandem mass 
      spectrometry (GC-MS/MS). The influence of the fibre coating used, the extraction 
      times and temperatures, the sodium chloride additions and the desorption 
      temperatures were investigated. Once done, the optimial HS-SPME conditions 
      established were divinylbenzene/carboxenpolydimethylsiloxane/polydimethylsiloxane 
      (DVB/CAR/PDMS) fibres, a 50 degrees C extraction temperature, 60-min extraction time, an 
      ionic strength of 3-g sodium chlorid and a 290 degrees C desorption temperature. The 
      method showed a good linearity (R(2)  >/= 0.994) within the tested range (from 0.1 
      to 50 ng L(-1) ) for all the compounds. Using TCA-d10 and MIB-d3 as internal 
      standards the precision, expressed as repeatability and reproducibility RSD, was 
      <10% in both. Note that the limits of quantifications (LOQs) are below the 
      sensory threshold levels for such compounds in water and wine. Good recoveries 
      were obtained for cork macerates (from 100.4% to 126%) and when compared with 
      other reported methods using HS-SPME in water and cork stopper samples, the 
      present method had more analytes with the lowest limit of detection for most of 
      the targeted compounds, along with good precision and recovery.
CI  - (c) 2021 John Wiley & Sons, Ltd.
FAU - Jove, Patricia
AU  - Jove P
AUID- ORCID: 0000-0002-3435-8444
AD  - Catalan Cork Institute and Foundation, Institut Catala del Suro (ICSuro), Girona, 
      Spain.
FAU - Pareras, Anna
AU  - Pareras A
AD  - Institute of Food and Agricultural Technology-CIDSAV-XaRTA, University of Girona, 
      Girona, Spain.
FAU - De Nadal, Raquel
AU  - De Nadal R
AD  - R&D department, J.VIGAS, Girona, Spain.
FAU - Verdum, Maria
AU  - Verdum M
AD  - Catalan Cork Institute and Foundation, Institut Catala del Suro (ICSuro), Girona, 
      Spain.
LA  - eng
PT  - Journal Article
DEP - 20210403
PL  - England
TA  - J Mass Spectrom
JT  - Journal of mass spectrometry : JMS
JID - 9504818
SB  - IM
OTO - NOTNLM
OT  - GC-Triple quadrupole MS
OT  - cork stoppers
OT  - earthy-musty compounds
OT  - headspace solid phase microextraction (HS-SPME)
EDAT- 2021/04/23 06:00
MHDA- 2021/04/23 06:00
CRDT- 2021/04/22 20:34
PHST- 2021/03/19 00:00 [revised]
PHST- 2021/01/09 00:00 [received]
PHST- 2021/03/30 00:00 [accepted]
PHST- 2021/04/22 20:34 [entrez]
PHST- 2021/04/23 06:00 [pubmed]
PHST- 2021/04/23 06:00 [medline]
AID - 10.1002/jms.4728 [doi]
PST - aheadofprint
SO  - J Mass Spectrom. 2021 Apr 3;56(5):e4728. doi: 10.1002/jms.4728.