PMID- 33895202
OWN - NLM
STAT- MEDLINE
DCOM- 20210921
LR  - 20210921
IS  - 1872-8111 (Electronic)
IS  - 0168-0102 (Linking)
VI  - 172
DP  - 2021 Nov
TI  - Role of the nucleus accumbens in functional recovery from spinal cord injury.
PG  - 1-6
LID - S0168-0102(21)00080-8 [pii]
LID - 10.1016/j.neures.2021.04.006 [doi]
AB  - Post brain damage depression impedes functional recovery. On the other hand, 
      higher motivation facilitates functional recovery after damage to the central 
      nervous system, but the neural mechanism of psychological effects on functional 
      recovery is unclear. The nucleus accumbens (NAcc), a motivation center, has not 
      been considered directly involved in motor function. Recently, it was 
      demonstrated that the NAcc makes a direct contribution to motor performance after 
      spinal cord injury by facilitating motor cortex activity. In this perspective, we 
      first summarize our investigation of role of NAcc in motor control during the 
      recovery course after spinal cord injury, followed by a discussion of the current 
      knowledge regarding the relationship between the recovery and NAcc after neuronal 
      damage.
CI  - Copyright (c) 2021 Elsevier B.V. and Japan Neuroscience Society. All rights 
      reserved.
FAU - Sawada, Masahiro
AU  - Sawada M
AD  - Department of Neurosurgery, University of Iowa, 200 Hawkins Drive, Iowa City, IA 
      52242, USA. Electronic address: masahiro-sawada@uiowa.edu.
FAU - Nishimura, Yukio
AU  - Nishimura Y
AD  - Neural Prosthetics Project, Tokyo Metropolitan Institute of Medical Science, 
      Japan.
LA  - eng
PT  - Journal Article
DEP - 20210422
PL  - Ireland
TA  - Neurosci Res
JT  - Neuroscience research
JID - 8500749
SB  - IM
MH  - Humans
MH  - *Motor Cortex
MH  - Neurons
MH  - Nucleus Accumbens
MH  - Recovery of Function
MH  - *Spinal Cord Injuries
OTO - NOTNLM
OT  - Functional recovery
OT  - Motor cortex
OT  - Nucleus accumbens
OT  - Rehabilitation
OT  - Spinal cord injury
EDAT- 2021/04/26 06:00
MHDA- 2021/09/22 06:00
CRDT- 2021/04/25 20:29
PHST- 2020/10/28 00:00 [received]
PHST- 2021/04/17 00:00 [revised]
PHST- 2021/04/21 00:00 [accepted]
PHST- 2021/04/26 06:00 [pubmed]
PHST- 2021/09/22 06:00 [medline]
PHST- 2021/04/25 20:29 [entrez]
AID - S0168-0102(21)00080-8 [pii]
AID - 10.1016/j.neures.2021.04.006 [doi]
PST - ppublish
SO  - Neurosci Res. 2021 Nov;172:1-6. doi: 10.1016/j.neures.2021.04.006. Epub 2021 Apr 
      22.