PMID- 33896560 OWN - NLM STAT- MEDLINE DCOM- 20210514 LR - 20210514 IS - 1873-4324 (Electronic) IS - 0003-2670 (Linking) VI - 1161 DP - 2021 May 29 TI - UiO-66 metal-organic frameworks/gold nanoparticles based substrates for SERS analysis of food samples. PG - 338464 LID - S0003-2670(21)00290-7 [pii] LID - 10.1016/j.aca.2021.338464 [doi] AB - Recently, metal-organic frameworks (MOFs) based substrates have shown great potential for the quantitative analysis of food samples by surface-enhanced Raman scattering (SERS) due to their unique properties. Herein, we developed two UiO-66 MOFs/gold nanoparticles (AuNPs) based substrates by self-assembly, including UiO-66/AuNPs suspension substrate and UiO-66(NH(2))/AuNPs/Nylon-66 flexible membrane substrate, for quantitative analysis of complex food samples by SERS. UiO-66/AuNPs suspension substrate was prepared for SERS-based determination of a carcinogenic heterocyclic amine in barbecue meat. UiO-66(NH(2))/AuNPs/Nylon-66 membrane substrate was fabricated for the simultaneous separation, enrichment, and in situ analysis of Sudan Red 7B in chilli products. The heterocyclic amine and Sudan dye in real samples could be detected and quantified with the recoveries of 82.3-110% and 84.5-114% and relative standard deviations (RSDs) of 3.1-11.0% and 1.9-5.6% (n = 3) by use of these two substrates, respectively. These two UiO-66/AuNPs based substrates combined molecular enrichment and SERS activity, achieving excellent analytical accuracy and widening SERS application in practical food safety analysis. CI - Copyright (c) 2021 Elsevier B.V. All rights reserved. FAU - Fu, Jingtai AU - Fu J AD - School of Chemistry, Sun Yat-sen University, Guangzhou, 510275, China. FAU - Lai, Huasheng AU - Lai H AD - School of Chemistry, Sun Yat-sen University, Guangzhou, 510275, China. FAU - Zhang, Zhuomin AU - Zhang Z AD - School of Chemistry, Sun Yat-sen University, Guangzhou, 510275, China. Electronic address: zzm@mail.sysu.edu.cn. FAU - Li, Gongke AU - Li G AD - School of Chemistry, Sun Yat-sen University, Guangzhou, 510275, China. Electronic address: cesgkl@mail.sysu.edu.cn. LA - eng PT - Journal Article DEP - 20210328 PL - Netherlands TA - Anal Chim Acta JT - Analytica chimica acta JID - 0370534 RN - 0 (Metal-Organic Frameworks) RN - 7440-57-5 (Gold) SB - IM MH - Gold MH - *Metal Nanoparticles MH - *Metal-Organic Frameworks MH - Spectrum Analysis, Raman OTO - NOTNLM OT - Food safety OT - Heterocyclic amine OT - SERS OT - Sudan dye OT - UiO-66/AuNPs COIS- Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. EDAT- 2021/04/27 06:00 MHDA- 2021/05/15 06:00 CRDT- 2021/04/26 05:32 PHST- 2020/12/14 00:00 [received] PHST- 2021/03/23 00:00 [revised] PHST- 2021/03/24 00:00 [accepted] PHST- 2021/04/26 05:32 [entrez] PHST- 2021/04/27 06:00 [pubmed] PHST- 2021/05/15 06:00 [medline] AID - S0003-2670(21)00290-7 [pii] AID - 10.1016/j.aca.2021.338464 [doi] PST - ppublish SO - Anal Chim Acta. 2021 May 29;1161:338464. doi: 10.1016/j.aca.2021.338464. Epub 2021 Mar 28.