PMID- 33902142 OWN - NLM STAT- MEDLINE DCOM- 20211028 LR - 20211028 IS - 2567-5834 (Electronic) IS - 1434-1220 (Linking) VI - 49 IP - 2 DP - 2021 Apr TI - [The porcine respiratory disease complex (PRDC) - a clinical review]. PG - 120-132 LID - 10.1055/a-1403-1976 [doi] AB - The porcine respiratory disease complex describes a clinical condition that often manifests as treatment-resistant respiratory disease of growing to finishing pigs. Its multifactorial etiology includes infectious and non-infectious factors. Besides management and hygiene conditions, particularly viral and bacterial pathogens contribute to the development and course of PRDC. The porcine reproductive and respiratory syndrome virus (PRRSV), porcine circovirus type 2 (PCV2), influenza A virus (IAV) and Mycoplasma (M.) hyopneunoniae are considered as the major pathogens involved in PRDC. The clinical outcome and necropsy findings may differ depending on the involvement of the different pathogens. The complex nature of the PRDC impedes the diagnostic and preventive measures on affected farms. The present review provides insight into the pathomorphology, pathogenesis and inter-pathogen-interactions and aims to support practitioners in implementing purposeful diagnostic and preventive measures. CI - Thieme. All rights reserved. FAU - Eddicks, Matthias AU - Eddicks M AD - Klinik fur Schweine, Zentrum fur Klinische Tiermedizin, Ludwig-Maximilians-Universitat Munchen. FAU - Eddicks, Lina AU - Eddicks L AD - Institut fur Tierpathologie, Zentrum fur Klinische Tiermedizin, Ludwig-Maximilians-Universitat Munchen. FAU - Stadler, Julia AU - Stadler J AD - Klinik fur Schweine, Zentrum fur Klinische Tiermedizin, Ludwig-Maximilians-Universitat Munchen. FAU - Hermanns, Walter AU - Hermanns W AD - Institut fur Tierpathologie, Zentrum fur Klinische Tiermedizin, Ludwig-Maximilians-Universitat Munchen. FAU - Ritzmann, Mathias AU - Ritzmann M AD - Klinik fur Schweine, Zentrum fur Klinische Tiermedizin, Ludwig-Maximilians-Universitat Munchen. LA - ger PT - Journal Article PT - Review TT - Der Porcine Respiratory Disease Complex (PRDC) - eine klinische Ubersicht. DEP - 20210426 PL - Germany TA - Tierarztl Prax Ausg G Grosstiere Nutztiere JT - Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere JID - 9715779 SB - IM MH - Animals MH - *Circoviridae Infections/diagnosis/veterinary MH - *Circovirus MH - Farms MH - *Porcine Reproductive and Respiratory Syndrome/diagnosis/therapy MH - *Porcine respiratory and reproductive syndrome virus MH - *Respiratory Tract Diseases/veterinary MH - Swine MH - *Swine Diseases/diagnosis COIS- Die Autoren aus der Klinik fur Schweine halten regelmassig Vortrage auf Kongressen und Symposien. Diese Veranstaltungen werden teilweise oder ganzlich von Pharmafirmen gesponsert, die Produkte fur Schweine vertreiben. Aus dieser Tatigkeit ergab sich keinerlei Einfluss auf die Inhalte dieses Ubersichtsartikels. EDAT- 2021/04/27 06:00 MHDA- 2021/10/29 06:00 CRDT- 2021/04/26 20:32 PHST- 2021/04/26 20:32 [entrez] PHST- 2021/04/27 06:00 [pubmed] PHST- 2021/10/29 06:00 [medline] AID - 10.1055/a-1403-1976 [doi] PST - ppublish SO - Tierarztl Prax Ausg G Grosstiere Nutztiere. 2021 Apr;49(2):120-132. doi: 10.1055/a-1403-1976. Epub 2021 Apr 26.