PMID- 33903304
OWN - NLM
STAT- MEDLINE
DCOM- 20220223
LR  - 20220223
IS  - 0126-8635 (Print)
IS  - 0126-8635 (Linking)
VI  - 43
IP  - 1
DP  - 2021 Apr
TI  - A national audit of estimated glomerular filtration rate and proteinuria and the 
      MACD CKD task force recommendations.
PG  - 41-48
AB  - INTRODUCTION: The Malaysian Association of Clinical Biochemists (MACB) 
      established a Task Force for Chronic Kidney Disease. A survey was undertaken by 
      the Task Force on the reporting of estimated glomerular filtration rate (eGFR) 
      and urine albumin by hospital laboratories in Malaysia in both the government and 
      private sectors. MATERIALS AND METHODS: An e-mail invitation to participate in an 
      online survey was sent to hospital laboratories in Malaysia (n=140). Questions 
      regarding methods for measuring creatinine, equations for calculating eGFR, eGFR 
      reporting, the terminology used in reporting urine albumin, types of samples and 
      the cut-off values used for normal albuminuria. RESULTS: A total of 42/140 (30%) 
      laboratories answered the questionnaire. The prevalent method used for serum 
      creatinine measurement was the Jaffe method (88.1%) traceable to isotope-dilution 
      mass spectrometry. eGFR was reported along with serum creatinine by 61.9% of 
      laboratories while 33.3% of laboratories report eGFR on request. The formula used 
      for eGFR reporting was mainly MDRD (64.3%) and results were reported as exact 
      numbers even when the eGFR was <60 ml/min/1.73m(2). The term microalbumin is 
      still used by 83.3% of laboratories. There is a large heterogeneity among the 
      labs regarding the type of sample recommended for measuring urine albumin, 
      reference interval and reporting units. CONCLUSION: It is evident that the 
      laboratory assessment of chronic kidney disease in Malaysia is not standardised. 
      It is essential to provide a national framework for standardised reporting of 
      eGFR and urine albumin. Recommendations developed by the MACB CKD Task Force, if 
      adopted by all laboratories, will lead to a reduction in this variability.
FAU - Sthaneshwar, P
AU  - Sthaneshwar P
AD  - University Malaya, Faculty of Medicine, Department of Pathology, Kuala Lumpur, 
      Malaysia.
FAU - Lai, L C
AU  - Lai LC
AD  - Gleneagles Hospital, Kuala Lumpur, Malaysia. lesliecharleslai@gmail.com.
FAU - Raja Azzidin, R E
AU  - Raja Azzidin RE
FAU - Mohd Hussain, B
AU  - Mohd Hussain B
FAU - Anas, S S
AU  - Anas SS
FAU - Supremaniam, S
AU  - Supremaniam S
FAU - Lee, L Y
AU  - Lee LY
FAU - Mohamad Noor, N
AU  - Mohamad Noor N
FAU - Harun, H
AU  - Harun H
LA  - eng
PT  - Journal Article
PL  - Malaysia
TA  - Malays J Pathol
JT  - The Malaysian journal of pathology
JID - 8101177
RN  - 0 (Albumins)
RN  - AYI8EX34EU (Creatinine)
RN  - EC 2.7.10.1 (ErbB Receptors)
SB  - IM
MH  - Albumins
MH  - Creatinine
MH  - ErbB Receptors
MH  - Glomerular Filtration Rate
MH  - Humans
MH  - Proteinuria
MH  - *Renal Insufficiency, Chronic/diagnosis
EDAT- 2021/04/28 06:00
MHDA- 2022/02/24 06:00
CRDT- 2021/04/27 06:20
PHST- 2021/04/27 06:20 [entrez]
PHST- 2021/04/28 06:00 [pubmed]
PHST- 2022/02/24 06:00 [medline]
PST - ppublish
SO  - Malays J Pathol. 2021 Apr;43(1):41-48.