PMID- 33903657 OWN - NLM STAT- MEDLINE DCOM- 20211112 LR - 20211112 IS - 2045-2322 (Electronic) IS - 2045-2322 (Linking) VI - 11 IP - 1 DP - 2021 Apr 26 TI - Acute symptomatic vitreous floaters assessed with ultra-wide field scanning laser ophthalmoscopy and spectral domain optical coherence tomography. PG - 8930 LID - 10.1038/s41598-021-88371-9 [doi] LID - 8930 AB - To describe the eyes with vitreous floaters and to analyze the development of acute symptomatic posterior vitreous detachment (PVD). A retrospective review of medical records was performed on patients with the vitreous floater developed for the first time of their life. Peripapillary vitreous opacity (pVO) was searched in Ultra-wide field (UWF) scanning laser ophthalmoscopy and PVD stage was assessed through spectral-domain optical coherence tomography (SD-OCT). 196 patients (55 males and 141 females), who were 58.4 (+/- 9.1) years old, visited a retinal clinic 9.4 (+/- 9.1) days after they experienced vitreous floaters. In 196 eyes, pVO was noticed in 122 eyes (62.2%) at UWF. In 106 eyes where SD-OCT data were available, PVD was noticed in 100 eyes (94.3%). Symptomatic eyes showed more advanced stage of PVD (p < 0.001) than symptom free eyes. Eyes with floaters were more myopic (- 0.7 +/- 2.2D vs - 0.5 +/- 1.9D, p = 0.02), and had lower intraocular pressure (IOP) (14.7 +/- 3.2 mmHg vs 15.2 +/- 3.0 mmHg, p = 0.02) than the other symptom free eyes. In patients with first floater symptoms, PVD was in progress in most of the eyes not only the symptomatic eyes but also on the contralateral symptom free eyes. Eyes with vitreous floaters were more myopic and had lower IOP than the opposite symptom free eyes. FAU - Son, Gisung AU - Son G AD - Department of Retinal Service, Hangil Eye Hospital, Incheon, South Korea. AD - Department of Ophthalmology, Catholic Kwandong University College of Medicine, Incheon, 22711, South Korea. FAU - Sohn, Joonhong AU - Sohn J AD - Department of Retinal Service, Hangil Eye Hospital, Incheon, South Korea. FAU - Kong, Mingui AU - Kong M AD - Department of Retinal Service, Hangil Eye Hospital, Incheon, South Korea. eyedockong@gmail.com. AD - Department of Ophthalmology, Catholic Kwandong University College of Medicine, Incheon, 22711, South Korea. eyedockong@gmail.com. LA - eng PT - Journal Article DEP - 20210426 PL - England TA - Sci Rep JT - Scientific reports JID - 101563288 SB - IM MH - Acute Disease MH - Adult MH - Aged MH - Female MH - Humans MH - *Lasers MH - Male MH - Middle Aged MH - *Ophthalmoscopy MH - Retrospective Studies MH - *Tomography, Optical Coherence MH - Vitreous Body/*diagnostic imaging MH - Vitreous Detachment/*diagnostic imaging PMC - PMC8076170 COIS- The authors declare no competing interests. EDAT- 2021/04/28 06:00 MHDA- 2021/11/16 06:00 PMCR- 2021/04/26 CRDT- 2021/04/27 06:36 PHST- 2020/12/30 00:00 [received] PHST- 2021/04/08 00:00 [accepted] PHST- 2021/04/27 06:36 [entrez] PHST- 2021/04/28 06:00 [pubmed] PHST- 2021/11/16 06:00 [medline] PHST- 2021/04/26 00:00 [pmc-release] AID - 10.1038/s41598-021-88371-9 [pii] AID - 88371 [pii] AID - 10.1038/s41598-021-88371-9 [doi] PST - epublish SO - Sci Rep. 2021 Apr 26;11(1):8930. doi: 10.1038/s41598-021-88371-9.