PMID- 33906043
OWN - NLM
STAT- MEDLINE
DCOM- 20210705
LR  - 20220531
IS  - 1878-5506 (Electronic)
IS  - 1389-9457 (Linking)
VI  - 82
DP  - 2021 Jun
TI  - The effect of water-based intervention on sleep habits and two sleep-related 
      cytokines in children with autism.
PG  - 78-83
LID - S1389-9457(21)00216-1 [pii]
LID - 10.1016/j.sleep.2021.03.045 [doi]
AB  - OBJECTIVE: Previous studies have shown that children with autism have sleep 
      disturbances and elevated levels of pro-inflammatory cytokines. This study aimed 
      to evaluate the effect of aquatic exercise on sleep habits and two certain 
      sleep-related cytokines of children with autism spectrum disorders (ASD). 
      METHODS: Forty boys with ASD (aged 6-14) were recruited and randomly assigned to 
      an aquatic exercise (n = 20) or a control group (n = 20). Participants in aquatic 
      exercise group performed water-based activities for 10 weeks/2 sessions per 
      week/60 min, while control group didn't get any intervention. The serum levels of 
      Interleukin-1 beta (IL-1beta) and Tumor necrosis factor-alpha (TNF-alpha) and sleep quality 
      were measured before and after the intervention. RESULTS: Results revealed that 
      aquatic exercise may improve sleep quality and reduce the serum levels of IL-1beta 
      and TNF-alpha in children with ASD compared to control group. CONCLUSIONS: Overall, 
      it is recommended that physicians and educators should provide a safe and 
      effective exercise environment for ASD children to alleviate sleep issues and 
      inflammatory biomarkers.
CI  - Copyright (c) 2021 Elsevier B.V. All rights reserved.
FAU - Ansari, Soleyman
AU  - Ansari S
AD  - Department of Physical Education, Rasht Branch, Islamic Azad University, Rasht, 
      Iran. Electronic address: solomonansari@yahoo.com.
FAU - AdibSaber, Fahimeh
AU  - AdibSaber F
AD  - Department of Physical Education, Rasht Branch, Islamic Azad University, Rasht, 
      Iran. Electronic address: adibsaber@iaurasht.ac.ir.
FAU - Elmieh, Alireza
AU  - Elmieh A
AD  - Department of Physical Education, Rasht Branch, Islamic Azad University, Rasht, 
      Iran. Electronic address: elmieh1592@yahoo.com.
FAU - Gholamrezaei, Shahram
AU  - Gholamrezaei S
AD  - Department of Physical Education, Rasht Branch, Islamic Azad University, Rasht, 
      Iran. Electronic address: gholamrezaei@iaurasht.ac.ir.
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20210420
PL  - Netherlands
TA  - Sleep Med
JT  - Sleep medicine
JID - 100898759
RN  - 0 (Cytokines)
RN  - 059QF0KO0R (Water)
SB  - IM
MH  - Adolescent
MH  - *Autism Spectrum Disorder/complications/therapy
MH  - *Autistic Disorder
MH  - Child
MH  - Cytokines
MH  - Humans
MH  - Male
MH  - Sleep
MH  - *Sleep Wake Disorders/therapy
MH  - Water
OTO - NOTNLM
OT  - Aquatic training
OT  - Children with autism
OT  - Inflammatory cytokines
OT  - Sleep habits
EDAT- 2021/04/28 06:00
MHDA- 2021/07/06 06:00
CRDT- 2021/04/27 20:20
PHST- 2020/12/05 00:00 [received]
PHST- 2021/03/27 00:00 [revised]
PHST- 2021/03/31 00:00 [accepted]
PHST- 2021/04/28 06:00 [pubmed]
PHST- 2021/07/06 06:00 [medline]
PHST- 2021/04/27 20:20 [entrez]
AID - S1389-9457(21)00216-1 [pii]
AID - 10.1016/j.sleep.2021.03.045 [doi]
PST - ppublish
SO  - Sleep Med. 2021 Jun;82:78-83. doi: 10.1016/j.sleep.2021.03.045. Epub 2021 Apr 20.