PMID- 33911505 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220422 IS - 2005-3894 (Electronic) IS - 1013-9087 (Print) IS - 1013-9087 (Linking) VI - 30 IP - 6 DP - 2018 Dec TI - Increasing Prevalence of the Sensitization to Cat/Dog Allergens in Korea. PG - 662-667 LID - 10.5021/ad.2018.30.6.662 [doi] AB - BACKGROUND: Recently, the number of domestic pets has increased. As a consequence, sensitization to animal allergens, such as cat or dog allergens, has become a problem. OBJECTIVE: We studied the annual trends of sensitization to cats or dogs, and the characteristics of the patients. METHODS: We retrospectively analyzed the medical records of 7,469 patients who visited a dermatology clinic and underwent an allergic profile test, from January 2011 to December 2015. Specific immunoglobulin E (IgE) levels to cat or dog antibody greater than 3.50 IU/ml were regarded as positive results. RESULTS: In all, 274 patients showed significant increase in levels of specific IgE antibody to dog, and 307 revealed increase in levels of of specific IgE antibody to cat. The prevalence of these specific IgEs increased from 2011 to 2015. Independent risks for sensitization to cat allergens were sensitization to dog, but not to house dust, Dermatophagoides pteronyssinus, and D. farinae. Independent risks for sensitization to dog allergens were sensitization to cat, but not to house dust, D. pteronyssinus, and D. farinae. Total IgE level was not related to specific IgE level against either cats or dogs. CONCLUSION: In conclusion, the prevalence of sensitization to cat or dog has increased. Sensitization to cat or dog is related to each other, but is irrelevant to the total IgE level. CI - Copyright (c) 2018 The Korean Dermatological Association and The Korean Society for Investigative Dermatology. FAU - Park, Bok Won AU - Park BW AD - Department of Dermatology, Hallym University Sacred Heart Hospital, College of Medicine, Hallym University, Anyang, Korea. FAU - Park, Jun Yeong AU - Park JY AD - Department of Dermatology, Hallym University Sacred Heart Hospital, College of Medicine, Hallym University, Anyang, Korea. FAU - Cho, Eun Byul AU - Cho EB AD - Department of Dermatology, Hallym University Sacred Heart Hospital, College of Medicine, Hallym University, Anyang, Korea. FAU - Park, Eun Joo AU - Park EJ AD - Department of Dermatology, Hallym University Sacred Heart Hospital, College of Medicine, Hallym University, Anyang, Korea. FAU - Kim, Kwang Ho AU - Kim KH AUID- ORCID: 0000-0001-5315-6031 AD - Department of Dermatology, Hallym University Sacred Heart Hospital, College of Medicine, Hallym University, Anyang, Korea. FAU - Kim, Kwang Joong AU - Kim KJ AD - Department of Dermatology, Hallym University Sacred Heart Hospital, College of Medicine, Hallym University, Anyang, Korea. LA - eng PT - Journal Article DEP - 20181026 PL - Korea (South) TA - Ann Dermatol JT - Annals of dermatology JID - 8916577 PMC - PMC7992440 OTO - NOTNLM OT - Atopic dermatitis OT - Cat OT - Dog OT - Specific immunoglobulin E COIS- CONFLICTS OF INTEREST: The authors have nothing to disclose. EDAT- 2018/12/01 00:00 MHDA- 2018/12/01 00:01 PMCR- 2018/12/01 CRDT- 2021/04/29 06:21 PHST- 2018/03/15 00:00 [received] PHST- 2018/06/28 00:00 [revised] PHST- 2018/07/10 00:00 [accepted] PHST- 2021/04/29 06:21 [entrez] PHST- 2018/12/01 00:00 [pubmed] PHST- 2018/12/01 00:01 [medline] PHST- 2018/12/01 00:00 [pmc-release] AID - 10.5021/ad.2018.30.6.662 [doi] PST - ppublish SO - Ann Dermatol. 2018 Dec;30(6):662-667. doi: 10.5021/ad.2018.30.6.662. Epub 2018 Oct 26.