PMID- 33912489
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220422
IS  - 2251-7251 (Print)
IS  - 2251-726X (Electronic)
IS  - 2251-7251 (Linking)
VI  - 33
IP  - 115
DP  - 2021 Mar
TI  - IgG4-Related Laryngeal Disease as a Possible Cause of Idiopathic Subglottic 
      Stenosis: A Case Report.
PG  - 119-125
LID - 10.22038/ijorl.2020.47106.2547 [doi]
AB  - INTRODUCTION: Immunoglobulin G4-related disease (IgG4-RD) is a systemic 
      fibro-inflammatory disorder. Laryngotracheal manifestation is very rare; 
      therefore, it is usually associated with complex diagnostic and therapeutic 
      problems. CASE REPORT: Herein, we report the case of a 35-year-old woman with 
      idiopathic subglottic stenosis (ISGS) treated with one-step laryngotracheal 
      reconstruction surgery. Postoperatively, the lesion was found to be a part of the 
      IgG4-RD spectrum. Objective and subjective phoniatric tests, spirometry, and 
      Quality of Life Questionnaire were used for the evaluation of postoperative 
      functional results. Slide laryngotracheoplasty as a one-step surgery without 
      stenting and tracheostomy ensured a sufficiently wide subglottic space with no 
      adverse effect on voice quality. During a follow-up period of 22 months, 
      endoscopy and computed tomography scan revealed no significant restenosis. The 
      patient was able to return to premorbid activities of daily living without any 
      further medical treatment. CONCLUSION: The laryngeal involvement of IgG4-RD is 
      uncommon; however, it is a manifestation that should be included in the 
      differential diagnosis of subglottic stenoses (SGS). Furthermore, subglottic 
      IgG4-RD might be a potential etiological factor of ISGS and acquired airway 
      stenosis after short-term intubation. Slide laryngotracheoplasty might be a 
      favorable solution without stenting and tracheostomy even in special cases of 
      SGS.
FAU - Bach, Adam
AU  - Bach A
AD  - Department of Otorhinolaryngology & Head- Neck Surgery, University of Szeged; 
      Tisza Lajos krt. 111., 6725, Szeged, Hungary.
FAU - Ambrus, Andrea
AU  - Ambrus A
AD  - Department of Otorhinolaryngology & Head- Neck Surgery, University of Szeged; 
      Tisza Lajos krt. 111., 6725, Szeged, Hungary.
FAU - Ivanyi, Bela
AU  - Ivanyi B
AD  - Department of Pathology, University of Szeged, Allomas u. 2, 6725, Szeged, 
      Hungary.
FAU - Tobias, Zoltan
AU  - Tobias Z
AD  - Department of Otorhinolaryngology & Head- Neck Surgery, University of Szeged; 
      Tisza Lajos krt. 111., 6725, Szeged, Hungary.
FAU - Alim Marvasti, Gholam Hossein
AU  - Alim Marvasti GH
AD  - Department of Otorhinolaryngology & Head- Neck Surgery, University of Szeged; 
      Tisza Lajos krt. 111., 6725, Szeged, Hungary.
FAU - Rovo, Laszlo
AU  - Rovo L
AD  - Department of Otorhinolaryngology & Head- Neck Surgery, University of Szeged; 
      Tisza Lajos krt. 111., 6725, Szeged, Hungary.
LA  - eng
PT  - Case Reports
PL  - Iran
TA  - Iran J Otorhinolaryngol
JT  - Iranian journal of otorhinolaryngology
JID - 101577699
PMC - PMC8052487
OTO - NOTNLM
OT  - Fibro-inflammatory disorder
OT  - Idiopathic subglottic stenosis
OT  - IgG4
OT  - Laryngotracheoplasty
EDAT- 2021/04/30 06:00
MHDA- 2021/04/30 06:01
PMCR- 2021/03/01
CRDT- 2021/04/29 06:29
PHST- 2021/04/29 06:29 [entrez]
PHST- 2021/04/30 06:00 [pubmed]
PHST- 2021/04/30 06:01 [medline]
PHST- 2021/03/01 00:00 [pmc-release]
AID - 10.22038/ijorl.2020.47106.2547 [doi]
PST - ppublish
SO  - Iran J Otorhinolaryngol. 2021 Mar;33(115):119-125. doi: 
      10.22038/ijorl.2020.47106.2547.