PMID- 33915704
OWN - NLM
STAT- MEDLINE
DCOM- 20210514
LR  - 20210514
IS  - 1648-9144 (Electronic)
IS  - 1010-660X (Print)
IS  - 1010-660X (Linking)
VI  - 57
IP  - 4
DP  - 2021 Apr 1
TI  - Unicompartmental Knee Arthroplasty: Minimal Important Difference and Patient 
      Acceptable Symptom State for the Forgotten Joint Score.
LID - 10.3390/medicina57040324 [doi]
LID - 324
AB  - Background and Objectives: Unicompartmental knee arthroplasty (UKA) is a valid 
      alternative to total knee arthroplasties (TKAs) in selected cases. After surgery, 
      patients' experience and satisfaction were traditionally evaluated by pre- and 
      postsurgical scores and Patient-Reported Outcome Measures (PROMs). Otherwise, a 
      statistically significant change does not necessarily correlate to a clinically 
      meaningful improvement when measured using PROMs. To evaluate the real effect of 
      a specific treatment and understand the difference between groups in a clinical 
      trial, it is necessary to use a meaningful quantum of change on the score 
      assessed. The minimal clinically important difference (MCID) and the Patient 
      Acceptable Symptom State (PASS) can provide this meaningful change. This paper 
      aimed to calculate the MCID and the PASS of the Forgotten Joint Score (FJS-12) 
      after UKA. Materials and Methods: A total of 40 patients with a mean age 72.5 +/- 
      6.4 years undergoing UKA were assessed preoperatively and six months postsurgery 
      using the FJS-12 and the Oxford Knee Score (OKS). The baseline and 6-month 
      postoperative scores were compared using the Wilcoxon signed ranks test. The 
      correlation was calculated with Spearman's rho. Both distribution-based 
      approaches and anchor approaches were used to estimate MCID for the FJS-12. The 
      75th percentile and the Receiver operating characteristic (ROC) curve methods 
      were used to calculate the PASS of FJS-12. Results: MCID estimates for normalized 
      FJS-12 for UKA ranged from 5.68 to 19.82. The threshold of the FJS-12 with ROC 
      method was 72.92 (AUC = 0.76). The cut-off value computed with the 75th 
      percentile approach was 92.71. Conclusions: The MCID and PASS represent valid 
      tools to assess the real perception of clinical improvement in patients who 
      underwent UKA. The MCID value of FJS-12 was 12.5 for patients who underwent UKA. 
      The value of the PASS for the FJS-12 in patients who underwent UKA was 72.92.
FAU - Longo, Umile Giuseppe
AU  - Longo UG
AUID- ORCID: 0000-0003-4063-9821
AD  - Department of Orthopaedic and Trauma Surgery, Campus Bio-Medico University, Via 
      Alvaro del Portillo, 200, Trigoria, 00128 Rome, Italy.
FAU - De Salvatore, Sergio
AU  - De Salvatore S
AUID- ORCID: 0000-0002-9111-3638
AD  - Department of Orthopaedic and Trauma Surgery, Campus Bio-Medico University, Via 
      Alvaro del Portillo, 200, Trigoria, 00128 Rome, Italy.
FAU - Candela, Vincenzo
AU  - Candela V
AD  - Department of Orthopaedic and Trauma Surgery, Campus Bio-Medico University, Via 
      Alvaro del Portillo, 200, Trigoria, 00128 Rome, Italy.
FAU - Berton, Alessandra
AU  - Berton A
AUID- ORCID: 0000-0001-9767-7824
AD  - Department of Orthopaedic and Trauma Surgery, Campus Bio-Medico University, Via 
      Alvaro del Portillo, 200, Trigoria, 00128 Rome, Italy.
FAU - Casciaro, Carlo
AU  - Casciaro C
AUID- ORCID: 0000-0003-2496-1116
AD  - Department of Orthopaedic and Trauma Surgery, Campus Bio-Medico University, Via 
      Alvaro del Portillo, 200, Trigoria, 00128 Rome, Italy.
FAU - Sciotti, Gaia
AU  - Sciotti G
AD  - Research Unit Nursing Science, Campus Bio-Medico di Roma University, 00128 Rome, 
      Italy.
FAU - Cirimele, Giada
AU  - Cirimele G
AD  - Research Unit Nursing Science, Campus Bio-Medico di Roma University, 00128 Rome, 
      Italy.
FAU - Marchetti, Anna
AU  - Marchetti A
AD  - Research Unit Nursing Science, Campus Bio-Medico di Roma University, 00128 Rome, 
      Italy.
FAU - Piergentili, Ilaria
AU  - Piergentili I
AD  - Department of Orthopaedic and Trauma Surgery, Campus Bio-Medico University, Via 
      Alvaro del Portillo, 200, Trigoria, 00128 Rome, Italy.
FAU - De Marinis, Maria Grazia
AU  - De Marinis MG
AD  - Research Unit Nursing Science, Campus Bio-Medico di Roma University, 00128 Rome, 
      Italy.
FAU - Denaro, Vincenzo
AU  - Denaro V
AD  - Department of Orthopaedic and Trauma Surgery, Campus Bio-Medico University, Via 
      Alvaro del Portillo, 200, Trigoria, 00128 Rome, Italy.
LA  - eng
PT  - Journal Article
DEP - 20210401
PL  - Switzerland
TA  - Medicina (Kaunas)
JT  - Medicina (Kaunas, Lithuania)
JID - 9425208
SB  - IM
MH  - Aged
MH  - *Arthroplasty, Replacement, Knee
MH  - Humans
MH  - Knee Joint/surgery
MH  - *Osteoarthritis, Knee/surgery
MH  - Patient Reported Outcome Measures
MH  - Postoperative Period
MH  - Treatment Outcome
PMC - PMC8065647
OTO - NOTNLM
OT  - FJS-12
OT  - Forgotten Joint Score-12
OT  - MCID
OT  - PASS
OT  - UKA
OT  - unicompartmental knee arthroplasty
COIS- The authors declare no conflict of interest.
EDAT- 2021/05/01 06:00
MHDA- 2021/05/15 06:00
PMCR- 2021/04/01
CRDT- 2021/04/30 01:00
PHST- 2021/02/21 00:00 [received]
PHST- 2021/03/22 00:00 [revised]
PHST- 2021/03/24 00:00 [accepted]
PHST- 2021/04/30 01:00 [entrez]
PHST- 2021/05/01 06:00 [pubmed]
PHST- 2021/05/15 06:00 [medline]
PHST- 2021/04/01 00:00 [pmc-release]
AID - medicina57040324 [pii]
AID - medicina-57-00324 [pii]
AID - 10.3390/medicina57040324 [doi]
PST - epublish
SO  - Medicina (Kaunas). 2021 Apr 1;57(4):324. doi: 10.3390/medicina57040324.