PMID- 33916374 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20210502 IS - 2077-0383 (Print) IS - 2077-0383 (Electronic) IS - 2077-0383 (Linking) VI - 10 IP - 7 DP - 2021 Apr 5 TI - Translating Virtual Reality Cue Exposure Therapy for Binge Eating into a Real-World Setting: An Uncontrolled Pilot Study. LID - 10.3390/jcm10071511 [doi] LID - 1511 AB - Binge-eating disorder (BED) and bulimia nervosa (BN) have adverse psychological and medical consequences. Innovative interventions, like the integration of virtual reality (VR) with cue-exposure therapy (VR-CET), enhance outcomes for refractory patients compared to cognitive behavior therapy (CBT). Little is known about the feasibility and acceptability of translating VR-CET into real-world settings. To investigate this question, adults previously treated for BED or BN with at least one objective or subjective binge episode/week were recruited from an outpatient university eating disorder clinic to receive up to eight weekly one-hour VR-CET sessions. Eleven of 16 (68.8%) eligible patients were enrolled; nine (82%) completed treatment; and 82% (9/11) provided follow-up data 7.1 (SD = 2.12) months post-treatment. Overall, participant and therapist acceptability of VR-CET was high. Intent-to-treat objective binge episodes (OBEs) decreased significantly from 3.3 to 0.9/week (p < 0.001). Post-treatment OBE 7-day abstinence rate for completers was 56%, with 22% abstinent for 28 days at follow-up. Among participants purging at baseline, episodes decreased from a mean of one to zero/week, with 100% abstinence maintained at follow-up. The adoption of VR-CET into real-world clinic settings appears feasible and acceptable, with a preliminary signal of effectiveness. Findings, including some loss of treatment gains during follow-up may inform future treatment development. FAU - Nameth, Katherine AU - Nameth K AUID- ORCID: 0000-0003-1910-7302 AD - Department of Psychiatry and Behavioral Sciences, 401 Quarry Rd, Stanford University, Stanford, CA 94305, USA. FAU - Brown, Theresa AU - Brown T AUID- ORCID: 0000-0002-9261-3853 AD - PGSP-Stanford PsyD Consortium, 1791 Arastradero Rd, Palo Alto, CA 94304, USA. FAU - Bullock, Kim AU - Bullock K AD - Department of Psychiatry and Behavioral Sciences, 401 Quarry Rd, Stanford University, Stanford, CA 94305, USA. FAU - Adler, Sarah AU - Adler S AD - Department of Psychiatry and Behavioral Sciences, 401 Quarry Rd, Stanford University, Stanford, CA 94305, USA. FAU - Riva, Giuseppe AU - Riva G AUID- ORCID: 0000-0003-3657-106X AD - Applied Technology for Neuro-Psychology Lab. Istituto Auxologico Italiano, 20095 Milan, Italy. AD - Centro Studi e Ricerche di Psicologia della Comunicazione, Universita Cattolica del Sacro Cuore, 20123 Milan, Italy. FAU - Safer, Debra AU - Safer D AD - Department of Psychiatry and Behavioral Sciences, 401 Quarry Rd, Stanford University, Stanford, CA 94305, USA. FAU - Runfola, Cristin AU - Runfola C AD - Department of Psychiatry and Behavioral Sciences, 401 Quarry Rd, Stanford University, Stanford, CA 94305, USA. LA - eng GR - 133020/National Eating Disorders Association/ PT - Journal Article DEP - 20210405 PL - Switzerland TA - J Clin Med JT - Journal of clinical medicine JID - 101606588 PMC - PMC8038593 OTO - NOTNLM OT - binge eating OT - binge-eating disorder OT - bulimia nervosa OT - cue-exposure OT - eating disorder OT - therapy OT - treatment OT - virtual reality COIS- The authors declare no conflict of interest. EDAT- 2021/05/01 06:00 MHDA- 2021/05/01 06:01 PMCR- 2021/04/05 CRDT- 2021/04/30 01:03 PHST- 2021/03/02 00:00 [received] PHST- 2021/03/29 00:00 [revised] PHST- 2021/04/02 00:00 [accepted] PHST- 2021/04/30 01:03 [entrez] PHST- 2021/05/01 06:00 [pubmed] PHST- 2021/05/01 06:01 [medline] PHST- 2021/04/05 00:00 [pmc-release] AID - jcm10071511 [pii] AID - jcm-10-01511 [pii] AID - 10.3390/jcm10071511 [doi] PST - epublish SO - J Clin Med. 2021 Apr 5;10(7):1511. doi: 10.3390/jcm10071511.