PMID- 33923970 OWN - NLM STAT- MEDLINE DCOM- 20210520 LR - 20210520 IS - 1660-4601 (Electronic) IS - 1661-7827 (Print) IS - 1660-4601 (Linking) VI - 18 IP - 8 DP - 2021 Apr 20 TI - Toxic Organic Contaminants in Airborne Particles: Levels, Potential Sources and Risk Assessment. LID - 10.3390/ijerph18084352 [doi] LID - 4352 AB - In the last years, many studies have focused on risk assessment of exposure of workers to airborne particulate matter (PM). Several studies indicate a strong correlation between PM and adverse health outcomes, as a function of particle size. In the last years, the study of atmospheric particulate matter has focused more on particles less than 10 mum or 2.5 mum in diameter; however, recent studies identify in particles less than 0.1 mum the main responsibility for negative cardiovascular effects. The present paper deals with the determination of 66 organic compounds belonging to six different classes of persistent organic pollutants (POPs) in the ultrafine, fine and coarse fractions of PM (PM < 0.1 microm; 0.1 < PM < 2.5 microm and 2.5 < PM < 10 microm) collected in three outdoor workplaces and in an urban outdoor area. Data obtained were analyzed with principal component analysis (PCA), in order to underline possible correlation between sites and classes of pollutants and characteristic emission sources. Emission source studies are, in fact, a valuable tool for both identifying the type of emission source and estimating the strength of each contamination source, as useful indicator of environment healthiness. Moreover, both carcinogenic and non-carcinogenic risks were determined in order to estimate human health risk associated to study sites. Risk analysis was carried out evaluating the contribution of pollutant distribution in PM size fractions for all the sites. The results highlighted significant differences between the sites and specific sources of pollutants related to work activities were identified. In all the sites and for all the size fractions of PM both carcinogenic and non-carcinogenic risk values were below acceptable and safe levels of risks recommended by the regulatory agencies. FAU - Pomata, Donatella AU - Pomata D AUID- ORCID: 0000-0002-7967-6235 AD - Italian Workers' Compensation Authority via Roberto Ferruzzi 38, 00143 Rome, Italy. FAU - Di Filippo, Patrizia AU - Di Filippo P AUID- ORCID: 0000-0002-1929-1691 AD - Italian Workers' Compensation Authority via Roberto Ferruzzi 38, 00143 Rome, Italy. FAU - Riccardi, Carmela AU - Riccardi C AUID- ORCID: 0000-0002-3751-6049 AD - Italian Workers' Compensation Authority via Roberto Ferruzzi 38, 00143 Rome, Italy. FAU - Castellani, Federica AU - Castellani F AUID- ORCID: 0000-0003-0689-3789 AD - Department of Chemistry, Sapienza University of Rome, 00185 Rome, Italy. FAU - Simonetti, Giulia AU - Simonetti G AUID- ORCID: 0000-0002-6278-6905 AD - Department of Chemistry, Sapienza University of Rome, 00185 Rome, Italy. FAU - Sonego, Elisa AU - Sonego E AUID- ORCID: 0000-0003-4557-9311 AD - Department of Chemistry, Sapienza University of Rome, 00185 Rome, Italy. FAU - Buiarelli, Francesca AU - Buiarelli F AUID- ORCID: 0000-0001-5104-8854 AD - Department of Chemistry, Sapienza University of Rome, 00185 Rome, Italy. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20210420 PL - Switzerland TA - Int J Environ Res Public Health JT - International journal of environmental research and public health JID - 101238455 RN - 0 (Air Pollutants) RN - 0 (Environmental Pollutants) RN - 0 (Organic Chemicals) RN - 0 (Particulate Matter) SB - IM MH - *Air Pollutants/analysis MH - Environmental Monitoring MH - *Environmental Pollutants MH - Humans MH - Organic Chemicals MH - Particle Size MH - Particulate Matter/analysis MH - Risk Assessment PMC - PMC8073354 OTO - NOTNLM OT - organic pollutant measurements OT - outdoor environments OT - particle-size distribution OT - principal component analysis COIS- The authors declare no conflict of interest EDAT- 2021/05/01 06:00 MHDA- 2021/05/21 06:00 PMCR- 2021/04/20 CRDT- 2021/04/30 01:27 PHST- 2021/03/18 00:00 [received] PHST- 2021/04/16 00:00 [revised] PHST- 2021/04/18 00:00 [accepted] PHST- 2021/04/30 01:27 [entrez] PHST- 2021/05/01 06:00 [pubmed] PHST- 2021/05/21 06:00 [medline] PHST- 2021/04/20 00:00 [pmc-release] AID - ijerph18084352 [pii] AID - ijerph-18-04352 [pii] AID - 10.3390/ijerph18084352 [doi] PST - epublish SO - Int J Environ Res Public Health. 2021 Apr 20;18(8):4352. doi: 10.3390/ijerph18084352.