PMID- 33925075
OWN - NLM
STAT- MEDLINE
DCOM- 20210503
LR  - 20210518
IS  - 1424-8220 (Electronic)
IS  - 1424-8220 (Linking)
VI  - 21
IP  - 9
DP  - 2021 Apr 28
TI  - Evaluation of Prolonged Walking in Persons with Multiple Sclerosis: Reliability 
      of the Spatio-Temporal Walking Variables during the 6-Minute Walk Test.
LID - 10.3390/s21093075 [doi]
LID - 3075
AB  - BACKGROUND: Walking disorders represent the most disabling condition in persons 
      with Multiple Sclerosis (PwMS). Several studies showed good reliability of the 
      6-min walk test (6MWT) (i.e., especially distance traveled), but little is known 
      about the reliability of the Spatio-temporal (ST) variables in the 6MWT. 
      OBJECTIVE: To evaluate the test-retest reliability of ST variables and perceived 
      exertion during the 6MWT in PwMS and comparable healthy persons. METHODS: We 
      explored three 1-min intervals (initial: 0'-1', middle: 2'30''-3'30'', end: 5'-6') 
      of the 6MWT. Six ST variables and perceived exertion were measured (respectively, 
      using the GAITRite system and the Borg Scale). These measurements were performed 
      twice, 1 week apart. The test-retest effects were assessed using the intraclass 
      correlation coefficient (ICC) or the weighted kappa. RESULTS: Forty-five PwMS and 
      24 healthy persons were included. The test-retest reliability of ST variables 
      values was good-to-excellent for PwMS (ICC range: 0.858-0.919) and 
      moderate-to-excellent for healthy persons (ICC range: 0.569-0.946). The 
      test-retest reliability values of perceived exertion were fair for PwMS (weighted 
      kappa range: 0.279-0.376) and substantial for healthy persons (weighted kappa 
      range: 0.734-0.788). CONCLUSION: The measurement of ST variables during these 
      6MWT intervals is reliable and applicable in clinical practice and research to 
      adapt rehabilitation care in PwMS.
FAU - Hadouiri, Nawale
AU  - Hadouiri N
AUID- ORCID: 0000-0001-7852-5593
AD  - Laboratory of Clinical Functional Exploration of Movement, University Hospital of 
      Besancon, F-25000 Besancon, France.
AD  - Clinical Investigation Center, University Hospital of Besancon, INSERM 1431, 
      F-25000 Besancon, France.
AD  - Department of Physical Medicine and Rehabilitation, Dijon-Bourgogne University 
      Hospital, F-21000 Dijon, France.
FAU - Monnet, Elisabeth
AU  - Monnet E
AUID- ORCID: 0000-0002-3347-2579
AD  - Clinical Investigation Center, University Hospital of Besancon, INSERM 1431, 
      F-25000 Besancon, France.
FAU - Gouelle, Arnaud
AU  - Gouelle A
AUID- ORCID: 0000-0002-2368-8448
AD  - Gait and Balance Academy, ProtoKinetics, Havertown, PA 19083, USA.
AD  - Laboratory Performance, Sante, Metrologie, Societe (EA7507), UFR STAPS, F-51100 
      Reims, France.
FAU - Decavel, Pierre
AU  - Decavel P
AUID- ORCID: 0000-0002-0567-7171
AD  - Laboratory of Clinical Functional Exploration of Movement, University Hospital of 
      Besancon, F-25000 Besancon, France.
AD  - Integrative and Clinical Neurosciences EA481, Bourgogne Franche-Comte University, 
      F-25000 Besancon, France.
AD  - Rehabilitation Department, HFR, CH-1700 Fribourg, Switzerland.
FAU - Sagawa, Yoshimasa
AU  - Sagawa Y
AD  - Laboratory of Clinical Functional Exploration of Movement, University Hospital of 
      Besancon, F-25000 Besancon, France.
AD  - Clinical Investigation Center, University Hospital of Besancon, INSERM 1431, 
      F-25000 Besancon, France.
AD  - Integrative and Clinical Neurosciences EA481, Bourgogne Franche-Comte University, 
      F-25000 Besancon, France.
LA  - eng
GR  - 1/CX/CSRD VA/United States
PT  - Journal Article
DEP - 20210428
PL  - Switzerland
TA  - Sensors (Basel)
JT  - Sensors (Basel, Switzerland)
JID - 101204366
SB  - IM
MH  - *Disabled Persons
MH  - Exercise Test
MH  - Humans
MH  - *Multiple Sclerosis/diagnosis
MH  - Reproducibility of Results
MH  - Walk Test
MH  - Walking
PMC - PMC8125198
OTO - NOTNLM
OT  - 6MWT
OT  - multiple sclerosis
OT  - perceived exertion
OT  - reliability
OT  - walking
COIS- The authors have no conflict of interest or any financial and personal 
      relationships with other people or organizations that could inappropriately 
      influence their work to declare.
EDAT- 2021/05/01 06:00
MHDA- 2021/05/04 06:00
PMCR- 2021/04/28
CRDT- 2021/04/30 01:30
PHST- 2021/03/13 00:00 [received]
PHST- 2021/04/10 00:00 [revised]
PHST- 2021/04/26 00:00 [accepted]
PHST- 2021/04/30 01:30 [entrez]
PHST- 2021/05/01 06:00 [pubmed]
PHST- 2021/05/04 06:00 [medline]
PHST- 2021/04/28 00:00 [pmc-release]
AID - s21093075 [pii]
AID - sensors-21-03075 [pii]
AID - 10.3390/s21093075 [doi]
PST - epublish
SO  - Sensors (Basel). 2021 Apr 28;21(9):3075. doi: 10.3390/s21093075.