PMID- 33929793
OWN - NLM
STAT- MEDLINE
DCOM- 20211209
LR  - 20230324
IS  - 1873-4502 (Electronic)
IS  - 0886-3350 (Linking)
VI  - 47
IP  - 12
DP  - 2021 Dec 1
TI  - Safety of phakic intraocular collamer lens implantation in 95 highly myopic 
      special-needs children.
PG  - 1519-1523
LID - 10.1097/j.jcrs.0000000000000678 [doi]
AB  - PURPOSE: To assess the safety of intraocular collamer lens (ICL) implantation in 
      children with high ametropia by reporting rates and case specifics of 
      perioperative and longer-term adverse events (AEs).
. SETTING: St. Louis 
      Children's Hospital at Washington University Medical Center, St. Louis, Missouri. 
      DESIGN: Retrospective case series. METHODS: Clinical data were collated 
      retrospectively for 95 special-needs children (160 eyes) implanted with a Visian 
      ICL over the past 5 years. All surgeries were performed at St Louis Children's 
      Hospital under brief general anesthesia. The mean follow-up period was 2.0 +/- 1.4 
      years (range, 0.5 to 5.2). RESULTS: The mean age at implantation was 9.3 +/- 5.2 
      years (range, 1.8 to 25) and mean preoperative spherical equivalent refractive 
      error was -11.20 +/- 3.90 diopters (range, 4 to 22). 62 children (62/95, 65%) had a 
      neurodevelopmental disorder. 3 eyes (3/160, 2%) reported minor AE, consisting of 
      steroid-response ocular hypertension, which resolved with cessation of topical 
      steroid drops. Endothelial cell loss averaged 8.1% over 2 years, comparable with 
      that reported in ICL-implanted adults. The most common major AE (7 eyes [7/160, 
      4%]) was postoperative pupillary block, requiring revision of the peripheral 
      iridotomy. 1 child (1 eye [1/160, 0.6%]) with self-injurious behavior required 
      repair of a wound leak. 1 child (1 eye [1/160, 0.6%]) with Down syndrome 
      developed a cataract 2.8 years after ICL surgery, and 1 child (1 eye [1/160, 
      0.6%]) with severe autism spectrum disorder experienced traumatic retinal 
      detachment 1.2 years after implantation. CONCLUSIONS: The most common major AE 
      among the cohort with Visian ICL was pupillary block due to closure of the 
      iridotomy. Overall, the AE rate was low in this higher risk, difficult-to-manage 
      population of special-needs children.
CI  - Copyright (c) 2021 Published by Wolters Kluwer on behalf of ASCRS and ESCRS.
FAU - Reynolds, Margaret
AU  - Reynolds M
AD  - From the Departments of Ophthalmology and Visual Sciences (Reynolds, Hoekel, 
      Tychsen), Pediatrics (Reynolds, Tychsen), and Neuroscience (Tychsen) Washington 
      University in St. Louis School of Medicine, St. Louis, Missouri.
FAU - Hoekel, James
AU  - Hoekel J
FAU - Tychsen, Lawrence
AU  - Tychsen L
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Cataract Refract Surg
JT  - Journal of cataract and refractive surgery
JID - 8604171
SB  - IM
CIN - J Cataract Refract Surg. 2021 Dec 1;47(12):1605-1606. PMID: 34670949
MH  - *Autism Spectrum Disorder
MH  - Humans
MH  - Lens Implantation, Intraocular
MH  - *Myopia/surgery
MH  - *Phakic Intraocular Lenses
MH  - Retrospective Studies
EDAT- 2021/05/01 06:00
MHDA- 2021/12/15 06:00
CRDT- 2021/04/30 12:37
PHST- 2020/09/23 00:00 [received]
PHST- 2021/04/19 00:00 [accepted]
PHST- 2021/05/01 06:00 [pubmed]
PHST- 2021/12/15 06:00 [medline]
PHST- 2021/04/30 12:37 [entrez]
AID - 02158034-202112000-00006 [pii]
AID - 10.1097/j.jcrs.0000000000000678 [doi]
PST - ppublish
SO  - J Cataract Refract Surg. 2021 Dec 1;47(12):1519-1523. doi: 
      10.1097/j.jcrs.0000000000000678.